7AGC
Protease Sapp1p from Candida parapsilosis in complex with KB74
Summary for 7AGC
Entry DOI | 10.2210/pdb7agc/pdb |
Related | 3FV3 |
Descriptor | Candidapepsin, KB74, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (7 entities in total) |
Functional Keywords | secreted aspartic protease, virulence factor, candidiasis, peptidomimetic inhibitors, antibiotic |
Biological source | Candida parapsilosis More |
Total number of polymer chains | 8 |
Total formula weight | 147502.40 |
Authors | Dostal, J.,Heidingsfeld, O.,Brynda, J. (deposition date: 2020-09-22, release date: 2021-04-21, Last modification date: 2024-05-29) |
Primary citation | Dostal, J.,Brynda, J.,Vankova, L.,Zia, S.R.,Pichova, I.,Heidingsfeld, O.,Lepsik, M. Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis . J Enzyme Inhib Med Chem, 36:914-921, 2021 Cited by PubMed: 33843395DOI: 10.1080/14756366.2021.1906664 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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