7GPF
 
 | | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex with Z760048004 | | 分子名称: | DIMETHYL SULFOXIDE, N-(6-methylpyridin-2-yl)-D-prolinamide, Protease 3C | | 著者 | Lithgo, R.M, Fairhead, M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Godoy, A.S, Marples, P.G, Ni, X, Tomlinson, C.W.E, Thompson, W, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. | | 登録日 | 2023-08-24 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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7GPQ
 | | PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex with POB0008 | | 分子名称: | Protease 3C, methyl 1-(methanesulfonyl)-2-methyl-D-prolinate | | 著者 | Lithgo, R.M, Fairhead, M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Godoy, A.S, Marples, P.G, Ni, X, Tomlinson, C.W.E, Thompson, W, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. | | 登録日 | 2023-08-24 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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4AZ0
 | | crystal structure of cathepsin a, complexed with 8a. | | 分子名称: | (S)-3-{[1-(2-Fluoro-phenyl)-5-hydroxy-1H-pyrazole-3-carbonyl]-amino}-3-o-tolyl-propionic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | | 著者 | Ruf, S, Buning, C, Schreuder, H, Horstick, G, Linz, W, Olpp, T, Pernerstorfer, J, Hiss, K, Kroll, K, Kannt, A, Kohlmann, M, Linz, D, Huebschle, T, Ruetten, H, Wirth, K, Schmidt, T, Sadowski, T. | | 登録日 | 2012-06-22 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Novel Beta-Amino Acid Derivatives as Inhibitors of Cathepsin A.
J.Med.Chem., 55, 2012
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6TPW
 | | Crystal structures of FNIII domain one through four of the human leucocyte common antigen-related protein ( LAR) | | 分子名称: | Receptor-type tyrosine-protein phosphatase F, SULFATE ION | | 著者 | Vilstrup, J.P, Thirup, S.S, Simonsen, A, Birkefeldt, T, Strandbygaard, D. | | 登録日 | 2019-12-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal and solution structures of fragments of the human leucocyte common antigen-related protein.
Acta Crystallogr D Struct Biol, 76, 2020
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3U2S
 | | Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain ZM109 | | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | McLellan, J.S, Pancera, M, Kwong, P.D. | | 登録日 | 2011-10-04 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | | 主引用文献 | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
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5TBE
 | | Human p38alpha MAP Kinase in Complex with Dibenzosuberone Compound 2 | | 分子名称: | Mitogen-activated protein kinase 14, ~{N}-[2,4-bis(fluoranyl)-5-[[9-(2-morpholin-4-ylethylcarbamoyl)-11-oxidanylidene-5,6-dihydrodibenzo[1,2-~{d}:1',2'-~{f}][7]annulen-3-yl]amino]phenyl]thiophene-2-carboxamide | | 著者 | Buehrmann, M, Rauh, D. | | 登録日 | 2016-09-12 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Optimized Target Residence Time: Type I1/2 Inhibitors for p38 alpha MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine.
Angew. Chem. Int. Ed. Engl., 56, 2017
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1FH9
 | | CRYSTAL STRUCTURE OF THE XYLANASE CEX WITH XYLOBIOSE-DERIVED LACTAM OXIME INHIBITOR | | 分子名称: | BETA-1,4-XYLANASE, beta-D-xylopyranose-(1-4)-(2Z,3S,4S,5R)-2-hydroxyiminopiperidine-3,4,5-triol | | 著者 | Notenboom, V, Williams, S.J, Hoos, R, Withers, S.G, Rose, D.R. | | 登録日 | 2000-07-31 | | 公開日 | 2000-08-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.
Biochemistry, 39, 2000
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4O6B
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4O1Z
 | | Crystal Structure of Ovine Cyclooxygenase-1 Complex with Meloxicam | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, ... | | 著者 | Xu, S, Hermanson, D.J, Banerjee, S, Ghebreselasie, K, Clayton, G.M, Garavito, R.M, Marnett, L.J. | | 登録日 | 2013-12-16 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network.
J.Biol.Chem., 289, 2014
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1I1D
 | | CRYSTAL STRUCTURE OF YEAST GNA1 BOUND TO COA AND GLNAC-6P | | 分子名称: | 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, COENZYME A, GLUCOSAMINE-PHOSPHATE N-ACETYLTRANSFERASE, ... | | 著者 | Peneff, C, Mengin-Lecreulx, D, Bourne, Y. | | 登録日 | 2001-02-01 | | 公開日 | 2001-05-16 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase.
J.Biol.Chem., 276, 2001
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3ZM5
 | | CRYSTAL STRUCTURE OF MURF LIGASE IN COMPLEX WITH CYANOTHIOPHENE INHIBITOR | | 分子名称: | 2,4-bis(chloranyl)-N-[3-cyano-6-[(4-hydroxyphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]-5-morpholin-4-ylsulfonyl-benzamide, UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE | | 著者 | Hrast, M, Turk, S, Sosic, I, Knez, D, Randall, C.P, Barreteau, H, Contreras-Martel, C, Dessen, A, ONeill, A.J, Mengin-Lecreulx, D, Blanot, D, Gobec, S. | | 登録日 | 2013-02-05 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
Eur.J.Med.Chem., 66C, 2013
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4F7E
 | | Crystal structure of bovine CD1d with bound C16:0-alpha-galactosyl ceramide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | 著者 | Wang, J, Zajonc, D.M. | | 登録日 | 2012-05-15 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A' Pocket Unable to Bind Long-Chain Glycolipids.
Plos One, 7, 2012
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3O4O
 | | Crystal structure of an Interleukin-1 receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, ... | | 著者 | Wang, X.Q, Wang, D.L, Zhang, S.Y, Li, L, Liu, X, Mei, K.R. | | 登録日 | 2010-07-27 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural insights into the assembly and activation of IL-1beta with its receptors
Nat.Immunol., 11, 2010
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2ZGM
 | | Crystal structure of recombinant Agrocybe aegerita lectin,rAAL, complex with lactose | | 分子名称: | Anti-tumor lectin, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Li, D.F, Yang, N, Wang, D.C. | | 登録日 | 2008-01-23 | | 公開日 | 2009-01-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita
J.Mol.Biol., 387, 2009
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3E6J
 | | Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharide | | 分子名称: | GLYCEROL, SULFATE ION, Variable lymphocyte receptor diversity region, ... | | 著者 | Han, B.W, Herrin, B.R, Cooper, M.D, Wilson, I.A. | | 登録日 | 2008-08-15 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Antigen recognition by variable lymphocyte receptors.
Science, 321, 2008
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4GS7
 | | Structure of the Interleukin-15 quaternary complex | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ring, A.M, Ozkan, E, Feng, D, Garcia, K.C. | | 登録日 | 2012-08-27 | | 公開日 | 2012-11-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.
Nat.Immunol., 13, 2012
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5VWG
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1PO1
 | | POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION | | 分子名称: | (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY | | 著者 | Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M. | | 登録日 | 1997-01-08 | | 公開日 | 1997-12-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
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4H7U
 | | Crystal structure of pyranose dehydrogenase from Agaricus meleagris, wildtype | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... | | 著者 | Tan, T.C, Spadiut, O, Divne, C. | | 登録日 | 2012-09-20 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The 1.6 A crystal structure of pyranose dehydrogenase from Agaricus meleagris rationalizes substrate specificity and reveals a flavin intermediate.
Plos One, 8, 2013
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4B85
 | | Mus musculus Acetylcholinesterase in complex with 4-Chloranyl-N-(2- diethylamino-ethyl)-benzenesulfonamide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-chloranyl-N-[2-(diethylamino)ethyl]benzenesulfonamide, ACETYLCHOLINESTERASE, ... | | 著者 | Andersson, C.D, Forsgren, N, Akfur, C, Allgardsson, A, Berg, L, Qian, W, Ekstrom, F, Linusson, A. | | 登録日 | 2012-08-24 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors.
J.Med.Chem., 56, 2013
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3RT1
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3Q25
 | | Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) | | 分子名称: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | | 著者 | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2010-12-19 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
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3GNA
 | | Crystal structure of the RAG1 nonamer-binding domain with DNA | | 分子名称: | 5'-D(*AP*CP*TP*TP*AP*AP*CP*AP*AP*AP*AP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*TP*TP*TP*TP*GP*TP*TP*AP*AP*G)-3', V(D)J recombination-activating protein 1 | | 著者 | Yin, F.F, Bailey, S, Innis, C.A, Steitz, T.A, Schatz, D.G. | | 登録日 | 2009-03-16 | | 公開日 | 2009-04-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.
Nat.Struct.Mol.Biol., 16, 2009
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5FTP
 | | sulfur SAD phasing of Cdc23Nterm: data collection with a tailored X- ray beam size at 2.69 A wavelength (4.6 keV) | | 分子名称: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 8 | | 著者 | Cianci, M, Groves, M.R, Barford, D, Schneider, T.R. | | 登録日 | 2016-01-14 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Data Collection with a Tailored X-Ray Beam Size at 2.69 A Wavelength (4.6 Kev): Sulfur Sad Phasing of Cdc23Nterm
Acta Crystallogr.,Sect.D, 72, 2016
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3PHO
 | | Crystal structure of S64-4 in complex with PSBP | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose, S64-4 Fab (IgG1) heavy chain, S64-4 Fab (IgG1) light chain | | 著者 | Evans, D.W, Evans, S.V. | | 登録日 | 2010-11-04 | | 公開日 | 2011-05-18 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.
Glycobiology, 21, 2011
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