4H7U

Crystal structure of pyranose dehydrogenase from Agaricus meleagris, wildtype

Summary for 4H7U

• Entry DOI: 10.2210/pdb4h7u/pdb
• Descriptor: Pyranose dehydrogenase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-2,3,4-trihydroxy-5-[(4aR)-4a-hydroxy-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]pentyl dihydrogen diphosphate (non-preferred name), ... (6 entities in total)
• Functional Keywords: pyranose dehydrogenase, flavin adduct, gmc-oxidoreductase family, glycoprotein, rossmann fold/fad-linked reductases/alpha and beta proteins (a+b), oxidoreductase, fad binding, flavin c(4a) oxygen adduct, secreted
• Biological source: Leucoagaricus meleagris
• Cellular location: Secreted : Q3L245
• Total number of polymer chains: 1
• Total formula weight: 66292.73

Authors

Tan, T.C.,Spadiut, O.,Divne, C. (deposition date: 2012-09-20, release date: 2013-08-07, Last modification date: 2023-09-20)

• Primary citation: Tan, T.C.,Spadiut, O.,Wongnate, T.,Sucharitakul, J.,Krondorfer, I.,Sygmund, C.,Haltrich, D.,Chaiyen, P.,Peterbauer, C.K.,Divne, C.; The 1.6 A crystal structure of pyranose dehydrogenase from Agaricus meleagris rationalizes substrate specificity and reveals a flavin intermediate.; Plos One, 8:e53567-e53567, 2013; PubMed: 23326459; DOI: 10.1371/journal.pone.0053567

Experimental method

X-RAY DIFFRACTION (1.6 Å)