5NZC
 
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4R10
 | | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | | 分子名称: | 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ... | | 著者 | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | | 登録日 | 2014-08-03 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
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3FKB
 | | Structure of NDPK H122G and tenofovir-diphosphate | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Morera, S, Chen, Y.X. | | 登録日 | 2008-12-16 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Nucleoside diphosphate kinase and the activation of antiviral phosphonate analogs of nucleotides: binding mode and phosphorylation of tenofovir derivatives
Nucleosides Nucleotides Nucleic Acids, 28, 2009
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7E0F
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5NZB
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5O8W
 | | CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | | 分子名称: | Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ... | | 著者 | Wirth, C, Andersen, G.R, Hunte, C. | | 登録日 | 2017-06-14 | | 公開日 | 2017-08-23 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
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7EMF
 | | Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... | | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | | 登録日 | 2021-04-13 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
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3FZY
 | | Crystal Structure of Pre-cleavage Form of Cysteine Protease Domain from Vibrio cholerae RtxA Toxin | | 分子名称: | CHLORIDE ION, INOSITOL HEXAKISPHOSPHATE, RTX toxin RtxA, ... | | 著者 | Shuvalova, L, Minasov, G, Prochazkova, K, Satchell, K.J.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-01-26 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and molecular mechanism for autoprocessing of MARTX toxin of Vibrio cholerae at multiple sites
J.Biol.Chem., 284, 2009
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7F8J
 | | Cryo-EM structure of human pannexin-1 in a nanodisc | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | | 著者 | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | | 登録日 | 2021-07-02 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Sci.Signal., 15, 2022
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7F8N
 | | Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | | 著者 | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | | 登録日 | 2021-07-02 | | 公開日 | 2022-01-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Sci.Signal., 15, 2022
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7F8O
 | | Cryo-EM structure of the C-terminal deletion mutant of human PANX1 in a nanodisc | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | | 著者 | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | | 登録日 | 2021-07-02 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids.
Sci.Signal., 15, 2022
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5QU6
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5QU8
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5QU3
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5QUA
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5QU1
 | | Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A | | 分子名称: | Cytoplasmic protein NCK1, SULFATE ION | | 著者 | Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. | | 登録日 | 2019-12-13 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
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5QU5
 | | Domain Swap in the first SH3 domain of human Nck1 | | 分子名称: | Cytoplasmic protein NCK1 | | 著者 | Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. | | 登録日 | 2019-12-13 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | | 主引用文献 | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
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5QU2
 | | Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY | | 分子名称: | ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION | | 著者 | Rudolph, M.G. | | 登録日 | 2019-12-13 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
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5QU7
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5QU4
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4R11
 | | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | | 分子名称: | Cadherin-related hmr-1, IODIDE ION, Protein humpback-2 | | 著者 | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | | 登録日 | 2014-08-03 | | 公開日 | 2015-04-29 | | 実験手法 | X-RAY DIFFRACTION (2.789 Å) | | 主引用文献 | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
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3UK6
 | | Crystal Structure of the Tip48 (Tip49b) hexamer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 2 | | 著者 | Petukhov, M, Dagkessamanskaja, A, Bommer, M, Barrett, T, Tsaneva, I, Yakimov, A, Queval, R, Shvetsov, A, Khodorkovskiy, M, Kas, E, Grigoriev, M. | | 登録日 | 2011-11-09 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Large-Scale Conformational Flexibility Determines the Properties of AAA+ TIP49 ATPases.
Structure, 20, 2012
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6Z47
 | | Smooth muscle myosin shutdown state heads region | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin heavy chain 11, ... | | 著者 | Scarff, C.A, Carrington, G, Casas Mao, D, Chalovich, J.M, Knight, P.J, Ranson, N.A, Peckham, M. | | 登録日 | 2020-05-22 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | Structure of the shutdown state of myosin-2.
Nature, 588, 2020
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6EHR
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3J07
 | | Model of a 24mer alphaB-crystallin multimer | | 分子名称: | Alpha-crystallin B chain | | 著者 | Jehle, S, Vollmar, B, Bardiaux, B, Dove, K.K, Rajagopal, P, Gonen, T, Oschkinat, H, Klevit, R.E. | | 登録日 | 2011-04-27 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (20 Å), SOLID-STATE NMR, SOLUTION SCATTERING | | 主引用文献 | N-terminal domain of {alpha}B-crystallin provides a conformational switch for multimerization and structural heterogeneity.
Proc.Natl.Acad.Sci.USA, 108, 2011
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