5RXL
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![BU of 5rxl by Molmil](/molmil-images/mine/5rxl) | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1673618163 | 分子名称: | 4-amino-N-(2-hydroxyethyl)-N-methylbenzene-1-sulfonamide, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | 著者 | Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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5RY3
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![BU of 5ry3 by Molmil](/molmil-images/mine/5ry3) | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z2027158783 | 分子名称: | DIMETHYL SULFOXIDE, N-(2,1,3-benzoxadiazol-4-yl)acetamide, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | 著者 | Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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5RYK
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![BU of 5ryk by Molmil](/molmil-images/mine/5ryk) | INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1346370629 | 分子名称: | (3S,4R)-3-methyl-1-(methylsulfonyl)piperidin-4-amine, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | 著者 | Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2020-10-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024
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6Z08
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![BU of 6z08 by Molmil](/molmil-images/mine/6z08) | Crystal structure of cAMP-dependent protein kinase A (CHO PKA) in complex with 4-Nitrophenol | 分子名称: | P-NITROPHENOL, cAMP-dependent protein kinase catalytic subunit alpha | 著者 | Oebbeke, M, Siefker, C, Heine, A, Klebe, G. | 登録日 | 2020-05-08 | 公開日 | 2020-12-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Fragment Binding to Kinase Hinge: If Charge Distribution and Local pK a Shifts Mislead Popular Bioisosterism Concepts. Angew.Chem.Int.Ed.Engl., 60, 2021
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6ZG7
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![BU of 6zg7 by Molmil](/molmil-images/mine/6zg7) | bovine ATP synthase rotor domain, state 1 | 分子名称: | ATP synthase F(0) complex subunit C2, mitochondrial, ATP synthase subunit delta, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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3H1T
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![BU of 3h1t by Molmil](/molmil-images/mine/3h1t) | |
6ZIT
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![BU of 6zit by Molmil](/molmil-images/mine/6zit) | bovine ATP synthase Stator domain, state 2 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C2, ... | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-26 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6YT9
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![BU of 6yt9 by Molmil](/molmil-images/mine/6yt9) | Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit body | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | 登録日 | 2020-04-24 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
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7LEZ
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![BU of 7lez by Molmil](/molmil-images/mine/7lez) | Trimeric human Arginase 1 in complex with mAb1 - 2 hArg:2 mAb1 complex | 分子名称: | Arginase-1, MANGANESE (II) ION, mAb1 heavy chain, ... | 著者 | Gomez-Llorente, Y, Scapin, G, Palte, R.L. | 登録日 | 2021-01-15 | 公開日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | 主引用文献 | Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action. Commun Biol, 4, 2021
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6Z23
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![BU of 6z23 by Molmil](/molmil-images/mine/6z23) | Acylenzyme complex of cefotaxime bound to deacylation mutant KPC-2 (E166Q) | 分子名称: | CEFOTAXIME, C3' cleaved, open, ... | 著者 | Tooke, C.L, Hinchliffe, P, Spencer, J. | 登録日 | 2020-05-14 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational dynamics to extend antibiotic resistance. J.Biol.Chem., 296, 2020
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7LEY
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![BU of 7ley by Molmil](/molmil-images/mine/7ley) | Trimeric human Arginase 1 in complex with mAb5 | 分子名称: | Arginase-1, MANGANESE (II) ION, mAb5 heavy chain, ... | 著者 | Gomez-Llorente, Y, Scapin, G, Palte, R.L. | 登録日 | 2021-01-15 | 公開日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action. Commun Biol, 4, 2021
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7LEX
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![BU of 7lex by Molmil](/molmil-images/mine/7lex) | |
7LF0
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![BU of 7lf0 by Molmil](/molmil-images/mine/7lf0) | |
6Z6Y
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![BU of 6z6y by Molmil](/molmil-images/mine/6z6y) | |
7LF2
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![BU of 7lf2 by Molmil](/molmil-images/mine/7lf2) | Trimeric human Arginase 1 in complex with mAb4 | 分子名称: | Arginase-1, MANGANESE (II) ION, mAb4 monoclonal antibody heavy chain, ... | 著者 | Gomez-Llorente, Y, Scapin, G, Palte, R.L. | 登録日 | 2021-01-15 | 公開日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action. Commun Biol, 4, 2021
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7LNA
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![BU of 7lna by Molmil](/molmil-images/mine/7lna) | Infectious mammalian prion fibril (263K scrapie) | 分子名称: | Major prion protein | 著者 | Kraus, A, Hoyt, F, Schwartz, C.L, Hansen, B, Hughson, A.G, Artikis, E, Race, B, Caughey, B. | 登録日 | 2021-02-06 | 公開日 | 2021-09-01 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | High-resolution structure and strain comparison of infectious mammalian prions. Mol.Cell, 81, 2021
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7LF1
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![BU of 7lf1 by Molmil](/molmil-images/mine/7lf1) | Trimeric human Arginase 1 in complex with mAb3 | 分子名称: | Arginase-1, MANGANESE (II) ION, mAb3 heavy chain, ... | 著者 | Gomez-Llorente, Y, Scapin, G, Palte, R.L. | 登録日 | 2021-01-15 | 公開日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | 主引用文献 | Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action. Commun Biol, 4, 2021
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7LC9
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6YSI
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![BU of 6ysi by Molmil](/molmil-images/mine/6ysi) | Acinetobacter baumannii ribosome-tigecycline complex - 50S subunit | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | 登録日 | 2020-04-22 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Structure, 28, 2020
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6YV1
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![BU of 6yv1 by Molmil](/molmil-images/mine/6yv1) | Structure of human b(0,+)AT1 | 分子名称: | b(0,+)-type amino acid transporter 1 | 著者 | Wu, D, Safarian, S, Michel, H. | 登録日 | 2020-04-27 | 公開日 | 2021-01-20 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z24
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3H8K
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![BU of 3h8k by Molmil](/molmil-images/mine/3h8k) | Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution | 分子名称: | Autocrine motility factor receptor, isoform 2, Ubiquitin-conjugating enzyme E2 G2 | 著者 | Kalathur, R.C, Das, R, Li, J, Byrd, R.A, Ji, X. | 登録日 | 2009-04-29 | 公開日 | 2009-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78. Mol.Cell, 34, 2009
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6Z4U
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6Z6U
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![BU of 6z6u by Molmil](/molmil-images/mine/6z6u) | 1.25 A structure of human apoferritin obtained from Titan Mono-BCOR microscope | 分子名称: | Ferritin heavy chain, MAGNESIUM ION, SODIUM ION | 著者 | Yip, K.M, Fischer, N, Paknia, E, Chari, A, Stark, H. | 登録日 | 2020-05-29 | 公開日 | 2020-06-24 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (1.25 Å) | 主引用文献 | Atomic-resolution protein structure determination by cryo-EM. Nature, 587, 2020
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7LFV
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![BU of 7lfv by Molmil](/molmil-images/mine/7lfv) | |