7LF1
Trimeric human Arginase 1 in complex with mAb3
Summary for 7LF1
Entry DOI | 10.2210/pdb7lf1/pdb |
EMDB information | 23297 |
Descriptor | Arginase-1, mAb3 heavy chain, mAb3 light chain, ... (4 entities in total) |
Functional Keywords | arginase, metalloenzyme, immune system, hydrolase-immune system complex, hydrolase/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 18 |
Total formula weight | 648261.03 |
Authors | |
Primary citation | Palte, R.L.,Juan, V.,Gomez-Llorente, Y.,Bailly, M.A.,Chakravarthy, K.,Chen, X.,Cipriano, D.,Fayadat-Dilman, L.,Gathiaka, S.,Greb, H.,Hall, B.,Handa, M.,Hsieh, M.,Kofman, E.,Lin, H.,Miller, J.R.,Nguyen, N.,O'Neil, J.,Shaheen, H.,Sterner, E.,Strickland, C.,Sun, A.,Taremi, S.,Scapin, G. Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action. Commun Biol, 4:927-927, 2021 Cited by PubMed: 34326456DOI: 10.1038/s42003-021-02444-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.04 Å) |
Structure validation
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