PDB: 2107 件ウェブページステータス検索Chemie searchBIRD

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8VYE	SARS-CoV-2 S (C.37 Lambda variant) plus S309, S2L20, and S2X303 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, S2L20 Light Chain, ... 著者 McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2024-02-08 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features. Nat Commun, 15, 2024
8VYG	SARS-CoV-2 S RBD (C.37 Lambda variant) plus S309 Fab, local refinement 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Heavy Chain, S309 Light Chain, ... 著者 McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2024-02-08 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features. Nat Commun, 15, 2024
8VYF	SARS-CoV-2 S NTD (C.37 Lambda variant) plus S2L20 and S2X303 Fabs, local refinement 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, ... 著者 McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2024-02-08 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features. Nat Commun, 15, 2024
6M17	The 2019-nCoV RBD/ACE2-B0AT1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Guo, Y.Y, Zhou, Q. 登録日 2020-02-24 公開日 2020-03-11 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science, 367, 2020
6LNN	Crystal structure of MERS-CoV N-NTD complexed with ligand P4-1 分子名称: 5-propoxy-1H-indole, Nucleoprotein 著者 Hou, M.H, Lin, S.M, Hsu, J.N. 登録日 2019-12-31 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.634 Å) 主引用文献 Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation. Front Mol Biosci, 9, 2022
6M3M	Crystal structure of SARS-CoV-2 nucleocapsid protein N-terminal RNA binding domain 分子名称: Nucleoprotein 著者 Chen, S, Kang, S. 登録日 2020-03-04 公開日 2020-03-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites. Acta Pharm Sin B, 10, 2020
6LXT	Structure of post fusion core of 2019-nCoV S2 subunit 分子名称: Spike protein S2, TETRAETHYLENE GLYCOL, ZINC ION 著者 Zhu, Y, Sun, F. 登録日 2020-02-11 公開日 2020-02-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell Res., 30, 2020
6M39	Cryo-EM structure of SADS-CoV spike 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Ouyang, S, Hongxin, G. 登録日 2020-03-03 公開日 2020-08-26 最終更新日 2020-11-11 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Cryo-electron Microscopy Structure of the Swine Acute Diarrhea Syndrome Coronavirus Spike Glycoprotein Provides Insights into Evolution of Unique Coronavirus Spike Proteins. J.Virol., 94, 2020
6M1D	ACE2-B0AT1 complex, open conformation 分子名称: Angiotensin-converting enzyme 2, Sodium-dependent neutral amino acid transporter B(0)AT1 著者 Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Zhou, Q. 登録日 2020-02-25 公開日 2020-03-11 最終更新日 2020-04-08 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science, 367, 2020
6M18	ACE2-B0AT1 complex 分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Zhou, Q. 登録日 2020-02-25 公開日 2020-03-11 最終更新日 2020-11-04 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science, 367, 2020
6LZ6	Crystal structure of MERS-CoV N-NTD complexed with ligand P4-3 分子名称: 5-(2-fluoranylethoxy)-1H-indole, Nucleoprotein 著者 Hou, M.H, Lin, S.M, Hsu, J.N. 登録日 2020-02-18 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.646 Å) 主引用文献 Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation. Front Mol Biosci, 9, 2022
6LZ8	Crystal structure of MERS-CoV N-NTD complexed with ligand P4-4 分子名称: 5-(2-methoxyethoxy)-1H-indole, Nucleoprotein 著者 Hou, M.H, Lin, S.M, Hsu, J.N. 登録日 2020-02-18 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation. Front Mol Biosci, 9, 2022
6WNP	X-ray Structure of SARS-CoV-2 main protease bound to Boceprevir at 1.45 A 分子名称: 3C-like proteinase, boceprevir (bound form) 著者 Anson, B, Mesecar, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-04-23 公開日 2020-05-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.443 Å) 主引用文献 X-ray Structure of SARS-CoV-2 main protease bound to Boceprevir at 1.45 A To Be Published
6WZO	Structure of SARS-CoV-2 Nucleocapsid dimerization domain, P1 form 分子名称: Nucleoprotein 著者 Ye, Q, Corbett, K.D. 登録日 2020-05-14 公開日 2020-05-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein. Protein Sci., 29, 2020
6WXD	SARS-CoV-2 Nsp9 RNA-replicase 分子名称: Non-structural protein 9, SULFATE ION 著者 Littler, D.R, Gully, B.S, Riboldi-Tunnicliffe, A, Rossjohn, J. 登録日 2020-05-10 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9. Iscience, 23, 2020
6WPS	Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ... 著者 Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-04-27 公開日 2020-05-27 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody. Nature, 583, 2020
6WZQ	Structure of SARS-CoV-2 Nucleocapsid dimerization domain, P21 form 分子名称: Nucleoprotein, SULFATE ION 著者 Ye, Q, Corbett, K.D. 登録日 2020-05-14 公開日 2020-05-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein. Protein Sci., 29, 2020
6WRH	The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant 分子名称: CHLORIDE ION, GLYCEROL, Non-structural protein 3, ... 著者 Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Welk, L, Babnigg, G, Kim, Y, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-04-29 公開日 2020-05-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors. Nat Commun, 12, 2021
6WS6	Structural and functional analysis of a potent sarbecovirus neutralizing antibody 分子名称: O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), S309 antigen-binding (Fab) fragment, heavy chain, ... 著者 Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, Marco, A.D, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Telenti, A, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-04-30 公開日 2020-05-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody. Nature, 583, 2020
6WZT	CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cyno antibody heavy chain, ... 著者 Qiu, Y, Zhou, Y, Darricarrere, N. 登録日 2020-05-14 公開日 2021-03-10 最終更新日 2021-03-17 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates. Sci Transl Med, 13, 2021
7RW2	Cryo-EM structure of NTD-directed neutralizing antibody 5-7 in complex with prefusion SARS-CoV-2 spike glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-7 heavy chain, ... 著者 Cerutti, G, Shapiro, L. 登録日 2021-08-19 公開日 2021-09-01 最終更新日 2022-11-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain. Cell Rep, 37, 2021
7RZC	Papain-Like Protease of SARS CoV-2 in complex with Jun9-84-3 inhibitor 分子名称: (1R)-N-[(1H-indol-3-yl)methyl]-N-methyl-1-(naphthalen-1-yl)ethan-1-amine, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Osipiuk, J, Tesar, C, Endres, M, Wang, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-08-27 公開日 2021-09-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Papain-Like Protease of SARS CoV-2 in complex with Jun9-84-3 inhibitor To be Published
7SDR	Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor 分子名称: 1,2-ETHANEDIOL, 4-({methyl[(1R)-1-(naphthalen-1-yl)ethyl]amino}methyl)phenol, CHLORIDE ION, ... 著者 Osipiuk, J, Tesar, C, Endres, M, Wang, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-09-29 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor To be Published
7S0E	Structure of the SARS-CoV-2 S1 subunit in complex with antibody N-612-004 分子名称: N-612-004 Fab heavy chain, N-612-004 Light Chain, Spike glycoprotein 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2021-08-30 公開日 2021-10-06 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display. Cell Rep, 38, 2022
7S0D	Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-014 分子名称: N-612-014 Fab Heavy Chain, N-612-014 Light Chain, Spike glycoprotein 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2021-08-30 公開日 2021-10-06 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display. Cell Rep, 38, 2022

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