PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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7BV2	The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP) 分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... 著者 Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. 登録日 2020-04-09 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
2XI5	N-terminal endonuclease domain of La Crosse virus L-protein 分子名称: MANGANESE (II) ION, RNA POLYMERASE L 著者 Reguera, J, Weber, F, Cusack, S. 登録日 2010-06-28 公開日 2010-10-06 最終更新日 2012-07-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
2XI7	N-terminal endonuclease domain of La Crosse virus L-protein 分子名称: 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA POLYMERASE L 著者 Reguera, J, Weber, F, Cusack, S. 登録日 2010-06-28 公開日 2010-10-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
8PM0	Influenza A/H7N9 polymerase in replicase-like conformation in pre-initiation state with Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, Polymerase acidic protein, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-27 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8R3L	Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 3' vRNA end (51-mer vRNA loop), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2023-11-09 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8R3K	Influenza A/H7N9 polymerase in self-stalled pre-termination state, with Pol II pS5 CTD peptide mimic bound in site 1A/2A. 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Cusack, S. 登録日 2023-11-09 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
3UGP	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TATAAT) 分子名称: 5'-D(*TP*GP*TP*AP*TP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2011-11-02 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.697 Å) 主引用文献 Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
1TQL	POLIOVIRUS POLYMERASE G1A MUTANT 分子名称: ACETIC ACID, RNA-directed RNA polymerase 著者 Thompson, A.A, Peersen, O.B. 登録日 2004-06-17 公開日 2004-08-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase Embo J., 23, 2004
3UGO	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TACAAT) 分子名称: 5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2011-11-02 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
3C2P	X-ray crystal structure of the N4 mini-vRNAP P1 promoter complex 分子名称: P1 Promoter DNA, Virion RNA polymerase 著者 Gleghorn, M.L, Murakami, K.S. 登録日 2008-01-25 公開日 2008-12-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase. Mol.Cell, 32, 2008
3C3L	X-ray crystal structure of the N4 mini-vRNAP P2 promoter complex 分子名称: P2 Promoter DNA, Virion RNA polymerase 著者 Gleghorn, M.L, Murakami, K.S. 登録日 2008-01-28 公開日 2008-12-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase. Mol.Cell, 32, 2008
3C46	X-ray crystal structure of the N4 mini-vRNAP P2_7a promoter complex soaked with MgCl2 分子名称: DIHYDROGENPHOSPHATE ION, P2_7a Promoter DNA, Virion RNA polymerase 著者 Gleghorn, M.L, Murakami, K.S. 登録日 2008-01-29 公開日 2008-12-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase. Mol.Cell, 32, 2008
1P16	Structure of an mRNA capping enzyme bound to the phosphorylated carboxyl-terminal domain of RNA polymerase II 分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ... 著者 Fabrega, C, Shen, V, Shuman, S, Lima, C.D. 登録日 2003-04-11 公開日 2003-07-15 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II. Mol.Cell, 11, 2003
4GZK	Structure and interactions of the RNA-dependent RNA polymerase from bacteriophage phi12 分子名称: FORMIC ACID, MAGNESIUM ION, RNA-dependent RNA polymerase P2 著者 Ren, Z, Franklin, M, Ghose, R. 登録日 2012-09-06 公開日 2013-07-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structure of the RNA-directed RNA Polymerase from the cystovirus 12. Proteins, 81, 2013
1HMJ	SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H 分子名称: PROTEIN (SUBUNIT H) 著者 Thiru, A, Hodach, M, Eloranta, J, Kostourou, V, Weinzierl, R. 登録日 1999-02-05 公開日 1999-04-05 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 RNA polymerase subunit H features a beta-ribbon motif within a novel fold that is present in archaea and eukaryotes. J.Mol.Biol., 287, 1999
4FF3	N4 mini-vRNAP transcription initiation complex, 3 min after soaking GTP, ATP and Mn 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Bacteriophage N4 P2 promoter, GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Murakami, K.S, Basu, R.S. 登録日 2012-05-30 公開日 2012-12-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography. J.Biol.Chem., 288, 2013
4FF4	N4 mini-vRNAP transcription initiation complex, 4 min after soaking GTP, ATP and Mn 分子名称: ADENOSINE MONOPHOSPHATE, Bacteriophage N4 P2 promoter, GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Murakami, K.S. 登録日 2012-05-31 公開日 2012-12-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.026 Å) 主引用文献 Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography. J.Biol.Chem., 288, 2013
4FF1	N4 mini-vRNAP transcription initiation complex, 1 min after soaking GTP, ATP and Mn 分子名称: Bacteriophag N4 P2 promoter, PHOSPHATE ION, Virion RNA polymerase 著者 Murakami, K.S, Basu, R.S. 登録日 2012-05-30 公開日 2012-12-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography. J.Biol.Chem., 288, 2013
4FF2	N4 mini-vRNAP transcription initiation complex, 2 min after soaking GTP, ATP and Mn 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Bacteriophage N4 P2 promoter, GUANOSINE-5'-MONOPHOSPHATE, ... 著者 Murakami, K.S, Basu, R.S. 登録日 2012-05-30 公開日 2012-12-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography. J.Biol.Chem., 288, 2013
7AAP	Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP 分子名称: MAGNESIUM ION, Non-structural protein 12, Non-structural protein 7, ... 著者 Naydenova, K, Muir, K.W, Wu, L.F, Zhang, Z, Coscia, F, Peet, M, Castro-Hartman, P, Qian, P, Sader, K, Dent, K, Kimanius, D, Sutherland, J.D, Lowe, J, Barford, D, Russo, C.J. 登録日 2020-09-04 公開日 2020-09-23 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP. Proc.Natl.Acad.Sci.USA, 118, 2021
3E3J	Crystal Structure of an Intermediate Complex of T7 RNAP and 8nt of RNA 分子名称: DNA (28-MER), DNA (5'-D(*DTP*DAP*DAP*DTP*DAP*DCP*DGP*DAP*DCP*DTP*DCP*DAP*DCP*DTP*DAP*DTP*DAP*DTP*DTP*DTP*DCP*DTP*DGP*DCP*DCP*DAP*DAP*DAP*DCP*DGP*DGP*DC)-3'), DNA-directed RNA polymerase, ... 著者 Durniak, K.J, Bailey, S, Steitz, T.A. 登録日 2008-08-07 公開日 2008-11-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (6.7 Å) 主引用文献 The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation Science, 322, 2008
4NJC	RNA Polymerase interacting protein YkzG from Geobacillus stearothermophilus 分子名称: Geobacillus stearothermophilus YkzG 著者 Keller, A.N, Lewis, P.J. 登録日 2013-11-09 公開日 2014-08-20 最終更新日 2014-10-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 epsilon, a New Subunit of RNA Polymerase Found in Gram-Positive Bacteria J.Bacteriol., 196, 2014
7NFR	Fujian capmidlink domain in complex with Nb8194 分子名称: GLYCEROL, NB8194, Polymerase basic protein 2, ... 著者 Keown, J.R, Grimes, J.M, Fodor, E. 登録日 2021-02-07 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NFQ	Fujian capmidlink domain in complex with Nb8193 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Nb8193, ... 著者 Keown, J.R, Grimes, J.M, Fodor, E. 登録日 2021-02-07 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NFT	Fujian capbinding domain in complex with Nb8208 分子名称: Nb8208, Polymerase basic protein 2, SULFATE ION 著者 Keown, J.R, Grimes, J.M, Fodor, E. 登録日 2021-02-07 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022

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