PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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5OT7	Elongation factor G-ribosome complex captures in the absence of inhibitors. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Mace, K, Giudice, E, Chat, S, Gillet, R. 登録日 2017-08-21 公開日 2018-02-14 最終更新日 2025-04-09 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors. Nucleic Acids Res., 46, 2018
2A69	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-02 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2A68	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-01 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
4TYP	Crystal structure of an adenylate kinase mutant--AKm1 分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ZINC ION 著者 Moon, S, Bae, E. 登録日 2014-07-09 公開日 2014-11-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of thermally stable adenylate kinase mutants designed by local structural entropy optimization and structure-guided mutagenesis J KOREAN SOC APPL BIOL CHEM, 57, 2014
4L5Y	Methylthioadenosine phosphorylase from Schistosoma mansoni in APO form 分子名称: PHOSPHATE ION, S-methyl-5'-thioadenosine phosphorylase 著者 Torini, J.R, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2013-06-11 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.0957 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway. Plos Negl Trop Dis, 10, 2016
4LCO	Crystal structure of NE0047 with complex with substrate ammeline 分子名称: 4,6-diamino-1,3,5-triazin-2-ol, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION 著者 Bitra, A, Biswas, A, Anand, R. 登録日 2013-06-22 公開日 2014-01-22 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
4LCP	Crytsal structure of NE0047 in complex with 2,6-diaminopurine 分子名称: 9H-PURINE-2,6-DIAMINE, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION 著者 Bitra, A, Biswas, A, Anand, R. 登録日 2013-06-22 公開日 2014-01-22 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
4WD4	Crystal structure of human HO1 H25R 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE 著者 Caaveiro, J.M.M, Morante, K, Sigala, P, Tsumoto, K. 登録日 2014-09-06 公開日 2015-09-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis Biochemistry, 55, 2016
2I5D	Crystal Structure of Human Inosine Triphosphate Pyrophosphatase 分子名称: inosine triphosphate pyrophosphohydrolase 著者 Porta, J.C, Kozmin, S.G, Pavlov, Y.I, Borgstahl, G.E.O. 登録日 2006-08-24 公開日 2006-09-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Structure of the orthorhombic form of human inosine triphosphate pyrophosphatase. Acta Crystallogr.,Sect.F, 62, 2006
4LCN	Crytsal structure of NE0047 in complex with 2'-DEOXY-GUANOSINE 分子名称: 1,2-ETHANEDIOL, 2'-DEOXY-GUANOSINE, Cytidine and deoxycytidylate deaminase zinc-binding region, ... 著者 Anand, R, Bitra, A, Biswas, A. 登録日 2013-06-22 公開日 2014-01-22 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
4LD4	Crystal structure of NE0047 in complex with cytosine 分子名称: 6-AMINOPYRIMIDIN-2(1H)-ONE, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION 著者 Bitra, A, Biswas, A, Anand, R. 登録日 2013-06-24 公開日 2014-01-22 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
4V6X	Structure of the human 80S ribosome 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. 登録日 2013-02-27 公開日 2014-07-09 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structures of the human and Drosophila 80S ribosome. Nature, 497, 2013
2I8A	Salmonella typhimurium liganded by phosphate ion at 1.64A resolution 分子名称: PHOSPHATE ION, Uridine phosphorylase 著者 Timofeev, V.I, Gabdoulkhakov, A.G, Mikhailov, A.M. 登録日 2006-09-01 公開日 2007-09-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Salmonella typhimurium liganded by phosphate ion at 1.64A resolution To be Published
2J4E	THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE 分子名称: INOSINE 5'-TRIPHOSPHATE, INOSINE TRIPHOSPHATE PYROPHOSPHATASE, INOSINIC ACID, ... 著者 Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmbergschiavone, L, Hogbom, M, Kotenyova, T, Landry, R, Loppnau, P, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Schuler, H, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P. 登録日 2006-08-29 公開日 2006-09-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T. J.Biol.Chem., 282, 2007
4LRB	Phosphopentomutase S154G variant soaked with 2,3-dideoxyribose 5-phosphate 分子名称: 2,3-dideoxy-5-O-phosphono-alpha-D-ribofuranose, ACETATE ION, GLYCEROL, ... 著者 Birmingham, W.A, Starbird, C.A, Panosian, T.D, Nannemann, D.P, Iverson, T.M, Bachmann, B.O. 登録日 2013-07-19 公開日 2013-07-31 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nat.Chem.Biol., 10, 2014
2IKF	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP 分子名称: MAGNESIUM ION, RNA uridylyl transferase, URIDINE 5'-TRIPHOSPHATE 著者 Luecke, H, Stagno, J. 登録日 2006-10-02 公開日 2007-02-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 UTP-bound and Apo Structures of a Minimal RNA Uridylyltransferase. J.Mol.Biol., 366, 2007
2IQ5	Unliganded Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium at 1.90 A Resolution 分子名称: Uridine phosphorylase 著者 Timofeev, V.I, Dontsova, M.V, Gabdoulkhakov, A.G, Pavlyuk, B.P, Mikhailov, A.M. 登録日 2006-10-13 公開日 2007-10-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Unliganded Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium at 1.90 A Resolution To be Published
4EAF	Thymidine phosphorylase from E.coli 分子名称: GLYCEROL, SULFATE ION, Thymidine phosphorylase 著者 Timofeev, V.I, Abramchik, Y.A, Esipov, R.S, Kuranova, I.P. 登録日 2012-03-22 公開日 2013-03-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Thymidine phosphorylase from E.coli To be Published
8XRM	RNA polymerase II elongation complex with DSIF, SPT6, and ELOF1 transcribing genomic DNA extracted from human nuclei 分子名称: DNA, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Kujirai, T, Kato, J, Yamamoto, K, Hirai, S, Negishi, L, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2024-01-07 公開日 2025-05-07 最終更新日 2025-06-11 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis. Nat Commun, 16, 2025
8XSO	RNA polymerase II elongation complex transcribing genomic DNA extracted from human nuclei 分子名称: DNA, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Kujirai, T, Kato, J, Yamamoto, K, Hirai, S, Negishi, L, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2024-01-09 公開日 2025-05-07 最終更新日 2025-06-11 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis. Nat Commun, 16, 2025
6D9H	Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist 分子名称: ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Draper-Joyce, C.J, Khoshouei, M, Thal, D.M, Liang, Y.-L, Nguyen, A.T.N, Furness, S.G.B, Venugopal, H, Baltos, J, Plitzko, J.M, Danev, R, Baumeister, W, May, L.T, Wootten, D, Sexton, P, Glukhova, A, Christopoulos, A. 登録日 2018-04-29 公開日 2018-06-20 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the adenosine-bound human adenosine A1receptor-Gicomplex. Nature, 558, 2018
3NDP	Crystal structure of human AK4(L171P) 分子名称: Adenylate kinase isoenzyme 4, SULFATE ION 著者 Liu, R, Wang, Y, Wei, Z, Gong, W. 登録日 2010-06-07 公開日 2010-06-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion Biochem.Biophys.Res.Commun., 379, 2009
7K3W	Apoferritin structure at 1.36 angstrom resolution determined from a 300 kV Titan Krios G3i electron microscope with Falcon4 detector 分子名称: Ferritin heavy chain, SODIUM ION, ZINC ION 著者 Zhang, K, Pintilie, G, Li, S, Schmid, M, Chiu, W. 登録日 2020-09-14 公開日 2020-11-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (1.36 Å) 主引用文献 Resolving individual atoms of protein complex by cryo-electron microscopy. Cell Res., 30, 2020
4EAD	Thymidine phosphorylase from E.coli with 3'-azido-2'-fluoro-dideoxyuridine 分子名称: 2',3'-dideoxy-2'-fluoro-3'-triaza-1,2-dien-2-ium-1-yluridine, GLYCEROL, SULFATE ION, ... 著者 Timofeev, V.I, Abramchik, Y.A, Esipov, R.S, Kuranova, I.P. 登録日 2012-03-22 公開日 2013-03-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Thymidine phosphorylase from E.coli with 3'-azido-2'-fluoro-dideoxyuridine To be Published
4B6F	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function 分子名称: (4-phenoxyphenyl)methylazanium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3, ... 著者 Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. 登録日 2012-08-09 公開日 2012-10-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function. Nat.Chem.Biol., 8, 2012

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