8XRM

RNA polymerase II elongation complex with DSIF, SPT6, and ELOF1 transcribing genomic DNA extracted from human nuclei

Summary for 8XRM

• Entry DOI: 10.2210/pdb8xrm/pdb
• EMDB information: 38607
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, ... (21 entities in total)
• Functional Keywords: nucleus, transcription-rna-dna complex, transcription/rna/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 19
• Total formula weight: 897248.95

Authors

Kujirai, T.,Kato, J.,Yamamoto, K.,Hirai, S.,Negishi, L.,Ogasawara, M.,Takizawa, Y.,Kurumizaka, H. (deposition date: 2024-01-07, release date: 2025-05-07)

• Primary citation: Kujirai, T.,Kato, J.,Yamamoto, K.,Hirai, S.,Fujii, T.,Maehara, K.,Harada, A.,Negishi, L.,Ogasawara, M.,Yamaguchi, Y.,Ohkawa, Y.,Takizawa, Y.,Kurumizaka, H.; Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.13 Å)