PDB: 12060 件ウェブページステータス検索Chemie searchBIRD

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4ATI	MITF:M-box complex 分子名称: 5'-D(*AP*GP*GP*GP*TP*CP*AP*TP*GP*TP*GP*CP*TP*AP*AP*C)-3', 5'-D(*GP*TP*TP*AP*GP*CP*AP*CP*AP*TP*GP*AP*CP*CP*CP*T)-3', MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR 著者 Pogenberg, V, Deineko, V, Wilmanns, M. 登録日 2012-05-08 公開日 2012-12-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf Genes Dev., 26, 2012
4ATH	MITF apo structure 分子名称: MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR, SULFATE ION 著者 Pogenberg, V, Milewski, M, Wilmanns, M. 登録日 2012-05-08 公開日 2012-12-12 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf Genes Dev., 26, 2012
4B0Q	Lead Generation of BACE1 Inhibitors by Coupling Non-amidine New Warheads to a Known Binding Scaffold 分子名称: 2-[[3-(3-methoxyphenyl)phenyl]-(4-pyridyl)methyl]guanidine, ACETATE ION, BETA-SECRETASE 1 著者 Pendrill, R, Kolmodin, K, Johansson, P, Plobeck, N. 登録日 2012-07-04 公開日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Lead Generation of Bace1 Inhibitors by Coupling Non-Amidine New Warheads to a Known Binding Scaffold To be Published
4AVS	Structure of N-Acetyl-L-Proline bound to Serum Amyloid P Component 分子名称: 1-ACETYL-L-PROLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Kolstoe, S, Wood, S.P. 登録日 2012-05-29 公開日 2013-06-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
4ZX3	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10b 分子名称: DIMETHYL SULFOXIDE, M1 family aminopeptidase, MAGNESIUM ION, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-20 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4Z36	Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO-3080573 分子名称: (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, 1-(4-{[(2S,3R)-2-(2,3-dihydro-1H-inden-2-yloxy)-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]oxy}phenyl)cyclopropanecarboxylic acid, Lysophosphatidic acid receptor 1,Soluble cytochrome b562 著者 Chrencik, J.E, Roth, C.B, Terakado, M, Kurata, H, Omi, R, Kihara, Y, Warshaviak, D, Nakade, S, Asmar-Rovira, G, Mileni, M, Mizuno, H, Griffith, M.T, Rodgers, C, Han, G.W, Velasquez, J, Chun, J, Stevens, R.C, Hanson, M.A, GPCR Network (GPCR) 登録日 2015-03-30 公開日 2015-06-03 最終更新日 2015-07-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell, 161, 2015
4B55	Crystal Structure of the Covalent Adduct Formed between Mycobacterium marinum Aryalamine N-acetyltransferase and Phenyl vinyl ketone a derivative of Piperidinols 分子名称: 3-hydroxy-1-phenylpropan-1-one, ARYLAMINE N-ACETYLTRANSFERASE NAT 著者 Abuhammad, A, Fullam, E, Lowe, E.D, Staunton, D, Kawamura, A, Westwood, I.M, Bhakta, S, Garner, A.C, Wilson, D.L, Seden, P.T, Davies, S.G, Russell, A.J, Garman, E.F, Sim, E. 登録日 2012-08-02 公開日 2013-01-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Piperidinols that Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages. Plos One, 7, 2012
5AEA	Crystal structure of human NCAM domain 1 分子名称: CITRATE ANION, NEURAL CELL ADHESION MOLECULE 1 著者 Kvansakul, M, Griffiths, K, Foley, M. 登録日 2015-08-27 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 I-Bodies, Human Single Domain Antibodies that Antagonize Chemokine Receptor Cxcr4. J.Biol.Chem., 291, 2016
4AZ4	E.coli deformylase with Co(II) and hydrosulfide 分子名称: COBALT (II) ION, HYDROSULFURIC ACID, PEPTIDE DEFORMYLASE 著者 Palm, G.J, Hinrichs, W. 登録日 2012-06-22 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Fret Enzyme-Based Probe for Monitoring Hydrogen Sulfide. Inorg.Chem., 51, 2012
4ZY1	X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10r 分子名称: CARBONATE ION, GLYCEROL, N-{(1R)-2-(hydroxyamino)-1-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-2-oxoethyl}-2,2-dimethylpropanamide, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-21 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4XV2	B-Raf Kinase V600E oncogenic mutant in complex with Dabrafenib 分子名称: Dabrafenib, Serine/threonine-protein kinase B-raf 著者 zhang, Y, zhang, c. 登録日 2015-01-26 公開日 2015-10-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 RAF inhibitors that evade paradoxical MAPK pathway activation. Nature, 526, 2015
4ZYO	Crystal Structure of Human Integral Membrane Stearoyl-CoA Desaturase with Substrate 分子名称: Acyl-CoA desaturase, DODECYL-BETA-D-MALTOSIDE, STEAROYL-COENZYME A, ... 著者 Wang, H, Klein, M.G, Lane, W, Snell, G, Levin, I, Li, K, Zou, H, Sang, B.-C. 登録日 2015-05-21 公開日 2015-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate. Nat.Struct.Mol.Biol., 22, 2015
4Y0T	Crystal structure of apo form of OXA-58, a Carbapenem hydrolyzing Class D beta-lactamase from Acinetobacter baumanii (P21, 4mol/ASU) 分子名称: Beta-lactamase 著者 Pratap, S, Katiki, M, Gill, P, Golemi-Kotra, D, Kumar, P. 登録日 2015-02-06 公開日 2016-01-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D beta-Lactamase of Acinetobacter baumannii. Antimicrob.Agents Chemother., 60, 2015
4ATT	FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl para methoxy phenyl 分子名称: 3-(4-methoxyphenyl)prop-2-yn-1-yl alpha-D-mannopyranoside, FIMH 著者 Bouckaert, J, Touaibia, M, Roos, G, Shiao, T.C, Wang, Q, Papadopoulos, A, Roy, R. 登録日 2012-05-09 公開日 2013-05-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.251 Å) 主引用文献 Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of Fimh. Acs Med.Chem.Lett., 4, 2013
4AVT	Structure of CPHPC bound to Serum Amyloid P Component 分子名称: (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxidanylidene-hexanoyl]pyrrolidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Kolstoe, S.E, Purvis, A, Wood, S.P. 登録日 2012-05-29 公開日 2013-06-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc) Acta Crystallogr.,Sect.D, 70, 2014
2OVF	Crystal Structure of StaL-PAP complex 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, StaL 著者 Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2007-02-13 公開日 2007-02-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis. J.Biol.Chem., 282, 2007
5AES	Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in Complex with a PNP-derived Inhibitor 分子名称: GLYCEROL, MAGNESIUM ION, PYRIDOXAL PHOSPHATE PHOSPHATASE, ... 著者 Knobloch, G, Jabari, N, Koehn, M, Gohla, A, Schindelin, H. 登録日 2015-01-09 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.751 Å) 主引用文献 Synthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin. Bioorg.Med.Chem., 23, 2015
4APJ	Human angiotensin-converting enzyme in complex with BPPb 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, ANGIOTENSIN-CONVERTING ENZYME, ... 著者 Masuyer, G, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Acharya, K.R. 登録日 2012-04-03 公開日 2012-10-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular Recognition and Regulation of Human Angiotensin-I Converting Enzyme (Ace) Activity by Natural Inhibitory Peptides. Sci.Rep., 2, 2012
4XFZ	Structure of the native full-length HIV-1 capsid protein in complex with PF-3450074 (PF74) 分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ... 著者 Gres, A.T, Kirby, K.A, Sarafianos, S.G. 登録日 2014-12-29 公開日 2015-06-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability. Science, 349, 2015
400D	THE INTRINSIC STRUCTURE AND STABILITY OF OUT-OF-ALTERNATION BASE PAIRS IN Z-DNA 分子名称: DNA (5'-D(*(5CM)P*GP*GP*CP*(5CM)P*G)-3') 著者 Eichman, B.F, Basham, B, Schroth, G.P, Ho, P.S. 登録日 1998-05-28 公開日 1998-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The intrinsic structure and stability of out-of-alternation base pairs in Z-DNA. Nucleic Acids Res., 27, 1999
4ANW	Complexes of PI3Kgamma with isoform selective inhibitors. 分子名称: 3-AMINO-6-{4-CHLORO-3-[(2,3-DIFLUOROPHENYL)SULFAMOYL]PHENYL}-N-METHYLPYRAZINE-2-CARBOXAMIDE, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM, SULFATE ION 著者 Foster, P.G, Lougheed, J.C. 登録日 2012-03-22 公開日 2012-05-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 The Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase Gamma Inhibitors J.Med.Chem., 55, 2012
2PJ4	CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B [((R)-Benzyloxycarbonylamino-cyclohexyl-methyl)-hydroxy-phosphinoyloxy]-(3-guanidino-phenyl)-acetic acid COMPLEX 分子名称: (5R,6R,8S)-8-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-5-CYCLOHEXYL-6-HYDROXY-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE, Carboxypeptidase B, ZINC ION 著者 Adler, M, Whitlow, M. 登録日 2007-04-15 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of potent selective peptide mimetics bound to carboxypeptidase B. Acta Crystallogr.,Sect.D, 64, 2008
2PJ9	CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B 2-(3-Aminomethyl-phenyl)-3-{[(R)-1-(benzo[1,2,5]thiadiazole-4-sulfonylamino)-2-methyl-propyl]-hydroxy-phosphinoyl}-propionic acid COMPLEX 分子名称: (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(S)-{(1R)-1-[(2,1,3-BENZOTHIADIAZOL-4-YLSULFONYL)AMINO]-2-METHYLPROPYL}(HYDROXY)PHOSPHORYL]PROPANOIC ACID, Carboxypeptidase B, ZINC ION 著者 Adler, M, Whitlow, M. 登録日 2007-04-15 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structures of potent selective peptide mimetics bound to carboxypeptidase B. Acta Crystallogr.,Sect.D, 64, 2008
5AV4	Crystal structure of DAPK1-genistein complex in the presence of bromide ions. 分子名称: BROMIDE ION, Death-associated protein kinase 1, GENISTEIN 著者 Yokoyama, T, Mizuguchi, M. 登録日 2015-06-10 公開日 2015-10-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Insight into the Interactions between Death-Associated Protein Kinase 1 and Natural Flavonoids. J.Med.Chem., 58, 2015
5BOT	X-RAY Co-structure of MMP-13 with ethyl 5-carbamoyl-1H-indole-2-carboxylate 分子名称: CALCIUM ION, Collagenase 3, ZINC ION, ... 著者 Farrow, N.A, Padyana, A.K. 登録日 2015-05-27 公開日 2015-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13. J. Med. Chem., 54, 2011

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