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7K9X
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BU of 7k9x by Molmil
Aldolase, rabbit muscle (beam-tilt refinement x1)
分子名称: Fructose-bisphosphate aldolase A
著者Kearns, S.K, Cash, J.N, Cianfrocco, M.A.
登録日2020-09-29
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献High-resolution cryo-EM using beam-image shift at 200 keV.
Iucrj, 7, 2020
7K5X
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BU of 7k5x by Molmil
Cryo-EM structure of a chromatosome containing human linker histone H1.0
分子名称: DNA (197-MER), Histone H1.0, Histone H2A type 1-B/E, ...
著者Zhou, B.-R, Bai, Y.
登録日2020-09-17
公開日2020-11-25
最終更新日2021-01-20
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
2MZN
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BU of 2mzn by Molmil
NMR structure of the HLTF HIRAN domain in its DNA-bound conformation
分子名称: Helicase-like transcription factor
著者Korzhnev, D, Eldirany, S.
登録日2015-02-18
公開日2015-07-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.
Mol.Cell, 58, 2015
7K9L
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BU of 7k9l by Molmil
Aldolase, rabbit muscle (no beam-tilt refinement)
分子名称: Fructose-bisphosphate aldolase A
著者Cianfrocco, M.A, Kearns, S.E, Cash, J.N, Li, Y.
登録日2020-09-29
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献High-resolution cryo-EM using beam-image shift at 200 keV.
Iucrj, 7, 2020
7KA3
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BU of 7ka3 by Molmil
Aldolase, rabbit muscle (beam-tilt refinement x3)
分子名称: Fructose-bisphosphate aldolase A
著者Kearns, S.K, Cash, J.N, Cianfrocco, M.A, Li, Y.
登録日2020-09-29
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献High-resolution cryo-EM using beam-image shift at 200 keV.
Iucrj, 7, 2020
6T58
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BU of 6t58 by Molmil
Structure determination of the transactivation domain of p53 in complex with S100A4 using annexin A2 as a crystallization chaperone
分子名称: CALCIUM ION, Cellular tumor antigen p53,Protein S100-A4,Protein S100-A4,Annexin A2, GLYCEROL
著者Ecsedi, P, Gogl, G, Nyitray, L.
登録日2019-10-15
公開日2020-05-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone.
Structure, 28, 2020
7L5E
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BU of 7l5e by Molmil
Crystal Structure of KPT-330 bound to CRM1 (537-DLTVK-541 to GLCEQ)
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M, Chook, Y.M.
登録日2020-12-21
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.944 Å)
主引用文献Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol, 14, 2021
7KYZ
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BU of 7kyz by Molmil
Solution structures of full-length K-RAS bound to GDP
分子名称: Isoform 2B of GTPase KRas
著者Sharma, A.K, Maciag, A.E.
登録日2020-12-09
公開日2022-06-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structures of full-length K-RAS bound to GDP
To Be Published
5TKC
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BU of 5tkc by Molmil
Crystal structure of FBP aldolase from Toxoplasma gondii, ternary complex
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, GLYCERALDEHYDE-3-PHOSPHATE, ...
著者Heron, P.W, Sygusch, J.
登録日2016-10-06
公開日2017-10-04
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.779 Å)
主引用文献Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
2E9K
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BU of 2e9k by Molmil
Solution structure of the CH domain from human MICAL-2
分子名称: Protein MICAL-2
著者Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-01-25
公開日2007-07-31
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the CH domain from human MICAL-2
To be Published
2E8M
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BU of 2e8m by Molmil
Solution structure of the C-terminal SAM-domain of epidermal growth receptor pathway substrate 8
分子名称: Epidermal growth factor receptor kinase substrate 8
著者Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-01-22
公開日2007-07-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal SAM-domain of epidermal growth receptor pathway substrate 8
To be Published
5U4V
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BU of 5u4v by Molmil
pseudoGTPase domain (pG1) of p190RhoGAP-B
分子名称: Rho GTPase-activating protein 5
著者Stiegler, A.L, Boggon, T.J.
登録日2016-12-06
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献p190RhoGAP proteins contain pseudoGTPase domains.
Nat Commun, 8, 2017
5NZB
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BU of 5nzb by Molmil
A disulfide switch determines proteolytic resistance in the birch pollen allergen Bet v 2
分子名称: Profilin-2
著者Soh, W.T, Brandstetter, H.
登録日2017-05-12
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.
Int J Mol Sci, 18, 2017
5O8W
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BU of 5o8w by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
分子名称: Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ...
著者Wirth, C, Andersen, G.R, Hunte, C.
登録日2017-06-14
公開日2017-08-23
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
5TKP
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BU of 5tkp by Molmil
Crystal structure of FBP aldolase from Toxoplasma gondii, equilibrium Schiff base FBP complex
分子名称: 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase
著者Heron, P.W, Sygusch, J.
登録日2016-10-07
公開日2017-10-04
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
5TLZ
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BU of 5tlz by Molmil
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor naphthalene 2,6-bisphosphate
分子名称: Fructose-bisphosphate aldolase A, GLYCEROL, naphthalene-2,6-diyl bis[dihydrogen (phosphate)]
著者Heron, P.W, Sygusch, J.
登録日2016-10-12
公開日2017-10-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase.
J.Med.Chem., 61, 2018
5TAR
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BU of 5tar by Molmil
Crystal structure of farnesylated and methylated kras4b in complex with PDE-delta (crystal form II - with ordered hypervariable region)
分子名称: 1,2-ETHANEDIOL, FARNESYL, GTPase KRas, ...
著者Dharmaiah, S, Tran, T.H, Simanshu, D.K.
登録日2016-09-10
公開日2016-11-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of recognition of farnesylated and methylated KRAS4b by PDE delta.
Proc.Natl.Acad.Sci.USA, 113, 2016
5QU8
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BU of 5qu8 by Molmil
Crystal Structure of symmetric swapped human Nck SH3.1 domain, 0.93A, orthorhombic form IV
分子名称: Cytoplasmic protein NCK1, SODIUM ION
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (0.93 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU3
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BU of 5qu3 by Molmil
Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QUA
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BU of 5qua by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU1
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BU of 5qu1 by Molmil
Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A
分子名称: Cytoplasmic protein NCK1, SULFATE ION
著者Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU5
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BU of 5qu5 by Molmil
Domain Swap in the first SH3 domain of human Nck1
分子名称: Cytoplasmic protein NCK1
著者Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU2
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BU of 5qu2 by Molmil
Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY
分子名称: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU7
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BU of 5qu7 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU4
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BU of 5qu4 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020

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