PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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8P1B	Lysozyme structure solved from serial crystallography data collected at 2 kHz with JUNGFRAU detector at MAXIV 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C 著者 Nan, J, Leonarski, F, Furrer, A, Dworkowski, F. 登録日 2023-05-11 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Kilohertz serial crystallography with the JUNGFRAU detector at a fourth-generation synchrotron source. Iucrj, 10, 2023
8P1C	Lysozyme structure solved from serial crystallography data collected at 1 kHz with JUNGFRAU detector at MAXIV 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... 著者 Nan, J, Leonarski, F, Furrer, A, Dworkowski, F. 登録日 2023-05-11 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Kilohertz serial crystallography with the JUNGFRAU detector at a fourth-generation synchrotron source. Iucrj, 10, 2023
8P1A	Lysozyme structure solved from serial crystallography data collected at 2 kHz for 5 seconds with JUNGFRAU detector at MAXIV 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C 著者 Nan, J, Leonarski, F, Furrer, A, Dworkowski, F. 登録日 2023-05-11 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Kilohertz serial crystallography with the JUNGFRAU detector at a fourth-generation synchrotron source. Iucrj, 10, 2023
8P1D	Lysozyme structure solved from serial crystallography data collected at 100 Hz with JUNGFRAU detector at MAXIV 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... 著者 Nan, J, Leonarski, F, Furrer, A, Dworkowski, F. 登録日 2023-05-11 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Kilohertz serial crystallography with the JUNGFRAU detector at a fourth-generation synchrotron source. Iucrj, 10, 2023
6END	LTA4 hydrolase in complex with Compound15 分子名称: 4-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)benzaldehyde, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2017-10-04 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors. Sci Rep, 7, 2017
6ENC	LTA4 hydrolase in complex with Compound11 分子名称: 1-[[4-(1,3-benzothiazol-2-yloxy)phenyl]methyl]piperidine-4-carboxylic acid, ACETATE ION, IMIDAZOLE, ... 著者 Srinivas, H. 登録日 2017-10-04 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors. Sci Rep, 7, 2017
3HPR	Crystal structure of V148G adenylate kinase from E. coli, in complex with Ap5A 分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE 著者 Hilser, V.J, Travis, T.P, Bolen, D.W. 登録日 2009-06-04 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins. Proc.Natl.Acad.Sci.USA, 106, 2009
1PA0	CRYSTAL STRUCTURE OF BNSP-7, A LYS49-PHOSPHOLIPASE A2 分子名称: Myotoxic phospholipase A2-like 著者 Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R. 登録日 2003-05-13 公開日 2004-07-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights. Biochem.Biophys.Res.Commun., 311, 2003
7ESC	FmnB complexed with AMP 分子名称: ADENOSINE MONOPHOSPHATE, FAD:protein FMN transferase, MAGNESIUM ION 著者 Cheng, W, Zheng, Y.H. 登録日 2021-05-10 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Structural insights into the catalytic and inhibitory mechanisms of the flavin transferase FmnB in Listeria monocytogenes. MedComm (2020), 3, 2022
6VP7	Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2) 分子名称: Leucine-rich repeat serine/threonine-protein kinase 2 著者 Leschziner, A, Deniston, C, Lahiri, I. 登録日 2020-02-01 公開日 2020-08-26 最終更新日 2020-12-23 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of LRRK2 in Parkinson's disease and model for microtubule interaction. Nature, 588, 2020
3QAL	Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ... 著者 Yang, J, Wu, J, Steichen, J, Taylor, S.S. 登録日 2011-01-11 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold. J.Mol.Biol., 415, 2012
3SQP	Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity 分子名称: 5-methylphenazin-1(5H)-one, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Fritz-Wolf, K, Schirmer, R.H, Koenig, I, Goebel, U. 登録日 2011-07-06 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue. Redox Rep., 16, 2011
5M4V	X-ray structure of the mambaquaretin-1, a selective antagonist of the vasopressin type 2 receptor 分子名称: CHLORIDE ION, Mambaquaretin-1, S-1,2-PROPANEDIOL 著者 Stura, E.A, Vera, L, Ciolek, J, Mourier, G, Gilles, N. 登録日 2016-10-19 公開日 2017-05-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6W51	Structure of the antibody fragment H2 in complex with HLA-A*02:01/p53R175H 分子名称: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, Immunoglobulin heavy chain H2, ... 著者 Wright, K.M, Gabelli, S.B. 登録日 2020-03-12 公開日 2021-03-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.53 Å) 主引用文献 Targeting a neoantigen derived from a common TP53 mutation. Science, 371, 2021
138L	RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME 著者 Heinz, D.W, Matthews, B.W. 登録日 1993-09-01 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking. Protein Eng., 7, 1994
3NB7	Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin 分子名称: Penicillin-binding protein 1A 著者 Sliz, P, Yuan, Y, Walker, S. 登録日 2010-06-02 公開日 2011-05-18 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Functional and structural analysis of a key region of the cell wall inhibitor moenomycin. Acs Chem.Biol., 5, 2010
6WM1	Crystal structure of the Grb2 SH2 domain in complex with a tripeptide: Ac-pY-Ac6c-N-phenylpropyl 分子名称: ACE-PTR-02K-ASN-PRA, CALCIUM ION, CHLORIDE ION, ... 著者 Martin, S.F, Clements, J.H. 登録日 2020-04-20 公開日 2020-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Some thermodynamic effects of varying nonpolar surfaces in protein-ligand interactions. Eur.J.Med.Chem., 208, 2020
3NZB	Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Potent 5-(omega-carboxyl(alkyloxy)pyrido[2,-d]pyrimidine Derivatives 分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl 6-{3-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl]-4-methoxyphenoxy}hexanoate 著者 Cody, V. 登録日 2010-07-16 公開日 2010-12-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-([omega]-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives Acta Crystallogr.,Sect.D, 67, 2011
6WO2	Crystal Structure of the Grb2 SH2 Domain in Complex with a Tripeptide: Ac-pY-Ac6c-N-isohexyl 分子名称: ACE-PTR-02K-ASN-U67, CALCIUM ION, Growth factor receptor-bound protein 2, ... 著者 Martin, S.F, Clements, J.H. 登録日 2020-04-24 公開日 2020-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Some thermodynamic effects of varying nonpolar surfaces in protein-ligand interactions. Eur.J.Med.Chem., 208, 2020
3S8N	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide 分子名称: CHLORIDE ION, GLYCEROL, Growth factor receptor-bound protein 2, ... 著者 Clements, J.H, Stephen, F.M. 登録日 2011-05-29 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
7PB5	Crystal structure of CD73 in complex with UMP in the open form 分子名称: 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-07-30 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
6WRE	Crystal structure of mouse DXO in complex with 5'-OH RNA substrate mimic and calcium ion 分子名称: 3'-URIDINEMONOPHOSPHATE, CALCIUM ION, Decapping and exoribonuclease protein, ... 著者 Doamekpor, S.K, Tong, L. 登録日 2020-04-29 公開日 2020-05-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A novel 5'-hydroxyl dinucleotide hydrolase activity for the DXO/Rai1 family of enzymes. Nucleic Acids Res., 48, 2020
7PBB	Crystal structure of CD73 in complex with caffeine in the open form 分子名称: 5'-nucleotidase, CAFFEINE, CALCIUM ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-08-01 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
7PBA	Crystal structure of CD73 in complex with IMP in the open form 分子名称: 5'-nucleotidase, CALCIUM ION, GLYCEROL, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-08-01 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
6HRE	Paired helical filament from sporadic Alzheimer's disease brain 分子名称: Microtubule-associated protein tau 著者 Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M. 登録日 2018-09-26 公開日 2018-10-10 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta Neuropathol., 136, 2018

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