PDB: 1738 件ウェブページステータス検索Chemie searchBIRD

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7AYX	Structure of the cytochrome P450 AryC from Streptomyces roseosporus NRRL 15998 分子名称: Cytochrome P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Schneider, S, Schaefers, F, Gulder, T.A.M. 登録日 2020-11-13 公開日 2021-10-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Carrier Protein-Free Enzymatic Biaryl Coupling in Arylomycin A2 Assembly and Structure of the Cytochrome P450 AryC. Chemistry, 28, 2022
8VZ7	Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan 分子名称: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shah, M.B. 登録日 2024-02-11 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. J.Inorg.Biochem., 258, 2024
8SWL	Substrate free structure of cytochrome P450 CYP105Q4 from mycobacterium marinum 分子名称: Cytochrome P450 105Q4 Cyp105Q4, PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL 著者 Mohamed, H.A, Bruning, J.B, Bell, S.G. 登録日 2023-05-19 公開日 2024-03-27 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structural determination and characterisation of the CYP105Q4 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 754, 2024
5NCB	Crystal structure of Amycolatopsis cytochrome P450 GcoA in complex with guaiacol. 分子名称: Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE 著者 Mallinson, S.J.B, Johnson, C.W, Neidle, E.L, Beckham, G.T, McGeehan, J.E. 登録日 2017-03-03 公開日 2018-07-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion. Nat Commun, 9, 2018
1PO5	Structure of mammalian cytochrome P450 2B4 分子名称: Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Scott, E.E, He, Y.A, Wester, M.R, White, M.A, Chin, C.C, Halpert, J.R, Johnson, E.F, Stout, C.D. 登録日 2003-06-13 公開日 2003-10-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 An open conformation of mammalian cytochrome P450 2B4 at 1.6 A resolution Proc.Natl.Acad.Sci.USA, 100, 2003
3WKT	Complex structure of an open form of NADPH-cytochrome P450 reductase and heme oxygenase-1 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1, ... 著者 Sugishima, M, Sato, H, Higashimoto, Y, Harada, J, Wada, K, Fukuyama, K, Noguchi, M. 登録日 2013-10-31 公開日 2014-01-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Structural basis for the electron transfer from an open form of NADPH-cytochrome P450 oxidoreductase to heme oxygenase. Proc.Natl.Acad.Sci.USA, 111, 2014
1GJM	Covalent attachment of an electroactive sulphydryl reagent in the active site of cytochrome P450cam 分子名称: CYTOCHROME P450-CAM, N-(2-FERROCENYLETHYL)MALEIMIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Fulop, V. 登録日 2001-07-26 公開日 2001-07-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Covalent Attachment of an Electroactive Sulphydryl Reagent in the Active Site of Cytochrome P450Cam as Revealed by the Crystal Structure of the Modified Protein J.Am.Chem.Soc., 120, 1998
8EUH	cytochrome P450terp (cyp108A1) bound to alpha-terpineol 分子名称: 1,2-ETHANEDIOL, Cytochrome P450-terp, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Gable, J.A, Follmer, A.H, Poulos, T.L. 登録日 2022-10-18 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cooperative Substrate Binding Controls Catalysis in Bacterial Cytochrome P450terp (CYP108A1). J.Am.Chem.Soc., 2023
8EUK	cytochrome P450terp (cyp108A1) bound to ethylene glycol 分子名称: 1,2-ETHANEDIOL, Cytochrome P450-terp, PROTOPORPHYRIN IX CONTAINING FE 著者 Gable, J.A, Follmer, A.H, Poulos, T.L. 登録日 2022-10-18 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Cooperative Substrate Binding Controls Catalysis in Bacterial Cytochrome P450terp (CYP108A1). J.Am.Chem.Soc., 2023
8EUL	cytochrome P450terp (cyp108A1) mutant F188A bound to alpha-terpineol 分子名称: 1,2-ETHANEDIOL, Cytochrome P450-terp, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Gable, J.A, Follmer, A.H, Poulos, T.L. 登録日 2022-10-18 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Cooperative Substrate Binding Controls Catalysis in Bacterial Cytochrome P450terp (CYP108A1). J.Am.Chem.Soc., 2023
4R20	Zebra fish cytochrome P450 17A2 with Abiraterone 分子名称: Abiraterone, Cytochrome P450 family 17 polypeptide 2, MERCURY (II) ION, ... 著者 Pallan, P.S, Egli, M. 登録日 2014-08-08 公開日 2014-12-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2. J.Biol.Chem., 290, 2015
5VEU	Human Cytochrome P450 3A5 (CYP3A5) 分子名称: Cytochrome P450 3A5, PROTOPORPHYRIN IX CONTAINING FE, RITONAVIR 著者 Hsu, M.-H, Johnson, E.F. 登録日 2017-04-05 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 The X-Ray Crystal Structure of the Human Mono-Oxygenase Cytochrome P450 3A5-Ritonavir Complex Reveals Active Site Differences between P450s 3A4 and 3A5. Mol. Pharmacol., 93, 2018
1GEJ	STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM 分子名称: CYTOCHROME P450 55A1, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 lee, D.-S, Park, S.-Y, Yamane, K, Shiro, Y. 登録日 2000-11-13 公開日 2000-12-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam. Biochemistry, 40, 2001
3G5F	Crystallographic analysis of cytochrome P450 cyp121 分子名称: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Belin, P, Le Du, M.H, Gondry, M. 登録日 2009-02-05 公開日 2009-04-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
1GEI	STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM 分子名称: CYTOCHROME P450 55A1, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, D.-S, Park, S.-Y, Yamane, K, Shiro, Y. 登録日 2000-11-13 公開日 2000-11-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam. Biochemistry, 40, 2001
1GEM	STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM 分子名称: CYTOCHROME P450CAM, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, D.-S, Park, S.-Y, Yamane, K, Shiro, Y. 登録日 2000-11-13 公開日 2000-12-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam. Biochemistry, 40, 2001
1GEK	STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM 分子名称: CYTOCHROME P450CAM, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, D.-S, Park, S.-Y, Yamane, K, Shiro, Y. 登録日 2000-11-13 公開日 2000-12-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam. Biochemistry, 40, 2001
5VBU	Crystal Structure of Human Cytochrome P450 21A2 Hydroxyprogesterone Complex 分子名称: (9beta)-17-hydroxypregn-4-ene-3,20-dione, Cytochrome P450 21-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Pallan, P.S, Egli, M. 登録日 2017-03-30 公開日 2017-05-31 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia. J. Biol. Chem., 292, 2017
7QAN	Cytochrome P450 Enzyme AbyV 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, Cytochrome P450, ... 著者 Parnell, A.E, Back, C.R, Race, P.R. 登録日 2021-11-17 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis. Angew.Chem.Int.Ed.Engl., 62, 2023
8GK3	Cytochrome P450 3A7 in complex with Dehydroepiandrosterone sulfate 分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Cytochrome P450 3A7, PROTOPORPHYRIN IX CONTAINING FE 著者 Liu, J, Scott, E.E. 登録日 2023-03-16 公開日 2023-07-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate. J.Biol.Chem., 299, 2023
3NXU	Crystal structure of human cytochrome P4503A4 bound to an inhibitor ritonavir 分子名称: Cytochrome P450 3A4, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sevrioukova, I.F, Poulos, T.L. 登録日 2010-07-14 公開日 2010-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir. Proc.Natl.Acad.Sci.USA, 107, 2010
3TK3	Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole 分子名称: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Gay, S.C, Jang, H.H, Wilderman, P.R, Zhang, Q, Stout, C.D, Halpert, J.R. 登録日 2011-08-25 公開日 2011-11-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8001 Å) 主引用文献 Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme. Febs J., 279, 2012
3TJS	Crystal Structure of the complex between human cytochrome P450 3A4 and desthiazolylmethyloxycarbonyl ritonavir 分子名称: Cytochrome P450 3A4, N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Sevrioukova, I.F, Poulos, T.L. 登録日 2011-08-24 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Interaction of human cytochrome P4503A4 with ritonavir analogs. Arch.Biochem.Biophys., 520, 2012
5HDI	Structural characterization of CYP144A1, a Mycobacterium tuberculosis cytochrome P450 分子名称: Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE 著者 Chenge, J, Driscoll, M.D, McLean, K.J, Munro, A.W, Leys, D. 登録日 2016-01-05 公開日 2016-05-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis. Sci Rep, 6, 2016
3QE2	Crystal Structure of Human NADPH-Cytochrome P450 Reductase 分子名称: CALCIUM ION, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Xia, C, Marohnic, C, Panda, S.P, Masters, B.S, Kim, J.-J.P. 登録日 2011-01-19 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. Proc.Natl.Acad.Sci.USA, 108, 2011

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