PDB: 65 件ウェブページステータス検索Chemie searchBIRD

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8SUR	TMEM16F bound with Niclosamide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide, ... 著者 Feng, S, Cheng, Y. 登録日 2023-05-13 公開日 2023-09-06 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun, 14, 2023
8TAG	TMEM16F, with Calcium and PIP2, no inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anoctamin-6, CALCIUM ION 著者 Feng, S, Cheng, Y. 登録日 2023-06-27 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun, 14, 2023
8TAI	TMEM16F, with Calcium and PIP2, no inhibitor, Cl2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anoctamin-6, CALCIUM ION 著者 Wu, H, Feng, S, Cheng, Y. 登録日 2023-06-27 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun, 14, 2023
8TAL	TMEM16F, with Calcium and PIP2, no inhibitor, Cl1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anoctamin-6, CALCIUM ION 著者 Wu, H, Feng, S, Cheng, Y. 登録日 2023-06-27 公開日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun, 14, 2023
8TOI	nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (closed state) 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-03 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TOK	nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (open state) 分子名称: CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-03 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TOL	nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (open state) 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-03 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPM	nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+ 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPN	nhTMEM16 lipid scramblase in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ (intermediate state) 分子名称: CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPO	nhTMEM16 R432A mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPP	nhTMEM16 R432A mutant in lipid nanodiscs with MSP2N2 scaffold protein in the presence of Ca2+ 分子名称: CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPQ	nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long TM6) 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPR	nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (short TM6) 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPS	nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (bent TM6) 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024
8TPT	nhTMEM16 A444P mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (long TM6/short TM6) 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Lipid scramblase nhTMEM16 著者 Feng, Z, Accardi, A. 登録日 2023-08-04 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural basis of closed groove scrambling by a TMEM16 protein. Nat.Struct.Mol.Biol., 2024

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