8TAL

TMEM16F, with Calcium and PIP2, no inhibitor, Cl1

Summary for 8TAL

Entry DOI	10.2210/pdb8tal/pdb
EMDB information	41137
Descriptor	Anoctamin-6, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION (3 entities in total)
Functional Keywords	calcium-activated, ion channels, lipid scramblases, membrane protein
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	193297.29
Authors	Wu, H.,Feng, S.,Cheng, Y. (deposition date: 2023-06-27, release date: 2023-09-06)
Primary citation	Feng, S.,Puchades, C.,Ko, J.,Wu, H.,Chen, Y.,Figueroa, E.E.,Gu, S.,Han, T.W.,Ho, B.,Cheng, T.,Li, J.,Shoichet, B.,Jan, Y.N.,Cheng, Y.,Jan, L.Y. Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun, 14:4874-4874, 2023 Cited by PubMed: 37573365 DOI: 10.1038/s41467-023-40410-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation