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2VZ9
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Crystal Structure of Mammalian Fatty Acid Synthase in complex with NADP
分子名称: FATTY ACID SYNTHASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Maier, T, Leibundgut, M, Ban, N.
登録日2008-07-31
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
3G11
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Structure of E. coli FabF(C163Q) in complex with dihydrophenyl platensimycin
分子名称: 3-({3-[(1S,4S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxo-4-phenyldecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Soisson, S.M, Parthasarathy, G.
登録日2009-01-29
公開日2009-03-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis and biological evaluation of platensimycin analogs.
Bioorg.Med.Chem.Lett., 19, 2009
3G0Y
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Structure of E. coli FabF(C163Q) in complex with dihydroplatensimycin
分子名称: 3-({3-[(1S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxodecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Soisson, S.M, Parthasarathy, G.
登録日2009-01-29
公開日2009-03-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Synthesis and biological evaluation of platensimycin analogs.
Bioorg.Med.Chem.Lett., 19, 2009
2WGG
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Crystal Structure of Mycobacterium tuberculosis C171Q KasA variant with bound TLM
分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, DI(HYDROXYETHYL)ETHER, NONAETHYLENE GLYCOL, ...
著者Luckner, S.R, Kisker, C.
登録日2009-04-17
公開日2009-07-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
Structure, 17, 2009
2WGD
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Crystal structure of KasA of Mycobacterium tuberculosis
分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Luckner, S.R, Kisker, C.
登録日2009-04-17
公開日2009-07-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
Structure, 17, 2009
2WGE
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Crystal structure of KasA of Mycobacterium tuberculosis with bound TLM
分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Luckner, S.R, Kisker, C.
登録日2009-04-17
公開日2009-07-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
Structure, 17, 2009
2WGF
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Crystal structure of Mycobacterium tuberculosis C171Q KasA variant
分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, DI(HYDROXYETHYL)ETHER, SODIUM ION, ...
著者Luckner, S.R, Kisker, C.
登録日2009-04-17
公開日2009-07-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
Structure, 17, 2009
3HMJ
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Saccharomyces cerevisiae FAS type I
分子名称: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, FLAVIN MONONUCLEOTIDE, ...
著者Johansson, P, Mulinacci, B, Koestler, C, Vollrath, R, Oesterhelt, D, Grininger, M.
登録日2009-05-29
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase
Structure, 17, 2009
3KZU
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Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Brucella melitensis
分子名称: 1,2-ETHANEDIOL, 3-oxoacyl-(Acyl-carrier-protein) synthase ii, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-12-08
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Brucella melitensis
TO BE PUBLISHED
3HHD
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BU of 3hhd by Molmil
Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design.
分子名称: CHLORIDE ION, Fatty acid synthase
著者Pappenberger, G.M, Benz, J, Thoma, R, Rudolph, M.G.
登録日2009-05-15
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design.
J.Mol.Biol., 397, 2010
3HO9
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Structure of E.coli FabF(C163A) in complex with Platencin A1
分子名称: 2,4-dihydroxy-3-({3-[(2R,4aR,8S,8aR,9R)-9-hydroxy-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonap hthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Soisson, S.M, Parthasarathy, G.
登録日2009-06-01
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
3HNZ
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Structure of E. coli FabF(C163A) in Complex with Platensimycin
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, PLATENSIMYCIN
著者Soisson, S.M, Parthasarathy, G.
登録日2009-06-01
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
3HO2
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Structure of E.coli FabF(C163A) in complex with Platencin
分子名称: 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Soisson, S.M, Parthasarathy, G.
登録日2009-06-01
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
3LRF
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BU of 3lrf by Molmil
Crystal structure of beta-ketoacyl synthase from brucella melitensis
分子名称: Beta-ketoacyl synthase, SODIUM ION
著者Abendroth, J, Edwards, T, Staker, B, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-02-11
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.
Proteins, 88, 2020
3MQD
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BU of 3mqd by Molmil
Crystal structure of beta-ketoacyl synthase from brucella melitensis with FOL 0758, (1-methyl-1h-indazol-3-yl) methanol
分子名称: (5-thiophen-2-ylisoxazol-3-yl)methanol, Beta-ketoacyl synthase, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-04-28
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.
Proteins, 88, 2020
3I8P
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BU of 3i8p by Molmil
Crystal structure of E. coli FabF(C163A) in complex with Platensimycin A1
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Platensimycin A1
著者Soisson, S.M, Parthsarathy, G.
登録日2009-07-09
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
3O04
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BU of 3o04 by Molmil
Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes
分子名称: beta-keto-acyl carrier protein synthase II
著者Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-07-19
公開日2010-08-04
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes
To be Published
3OYT
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1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92
分子名称: 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase I, DI(HYDROXYETHYL)ETHER, ...
著者Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Peterson, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-09-23
公開日2011-01-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92
To be Published
3U0F
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BU of 3u0f by Molmil
The structure of Beta-ketoacyl synthase from Brucella melitensis bound to the fragment 7-hydroxycoumarin
分子名称: 7-hydroxy-2H-chromen-2-one, Beta-ketoacyl synthase, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-09-28
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.
Proteins, 88, 2020
3U0E
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BU of 3u0e by Molmil
Crystal structure of beta-ketoacyl synthase from Brucella melitensis in complex with fragment 9320
分子名称: 8-methylquinolin-4-amine, Beta-ketoacyl synthase, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-09-28
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.
Proteins, 88, 2020
4EWG
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BU of 4ewg by Molmil
Crystal structure of a Beta-ketoacyl synthase from Burkholderia phymatum STM815
分子名称: 1,2-ETHANEDIOL, Beta-ketoacyl synthase, CALCIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-04-26
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4DDO
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BU of 4ddo by Molmil
Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase ii from burkholderia vietnamiensis
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, SODIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-01-19
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4F32
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BU of 4f32 by Molmil
Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase II from Burkholderia vietnamiensis in complex with platencin
分子名称: 1,2-ETHANEDIOL, 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-05-08
公開日2012-05-23
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4JRM
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BU of 4jrm by Molmil
Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio Cholerae (space group P212121) at 1.75 Angstrom
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, ACETATE ION, GLYCEROL
著者Hou, J, Chruszcz, M, Shabalin, I.G, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-03-21
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio cholerae (space group P43) at 2.2 Angstrom
To be Published
4JRH
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Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio Cholerae (space group P43) at 2.2 Angstrom
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, ACETATE ION
著者Hou, J, Chruszcz, M, Shabalin, I.G, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-03-21
公開日2013-04-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献

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