6ESP
 
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5MZ7
 | | Crystal Structure of the third PDZ domain from the synaptic protein PSD-95 with incorporated Azidohomoalanine | | 分子名称: | Disks large homolog 4 | | 著者 | Kudlinzki, D, Lehner, F, Witt, K, Linhard, V.L, Silvers, R, Schwalbe, H. | | 登録日 | 2017-01-31 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding.
Chembiochem, 18, 2017
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6GBE
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6GBD
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5V6B
 | | Crystal structure of GIPC1 | | 分子名称: | PDZ domain-containing protein GIPC1 | | 著者 | Shang, G, Zhang, X. | | 登録日 | 2017-03-16 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
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5VWK
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5VWC
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5W72
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5ZYS
 | | Structure of Nephrin/MAGI1 complex | | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin | | 著者 | Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G. | | 登録日 | 2018-05-28 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling.
J. Am. Soc. Nephrol., 29, 2018
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6ZBQ
 | | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | | 分子名称: | 5-fluoranyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... | | 著者 | Roske, Y, Heinemann, U, Oschkinat, H. | | 登録日 | 2020-06-09 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
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6ZBZ
 | | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | | 分子名称: | 1,2-ETHANEDIOL, 2-[(3,4-dimethylphenyl)sulfonylamino]-5-fluoranyl-benzoic acid, Dishevelled, ... | | 著者 | Roske, Y, Heinemann, U, Oschkinat, H. | | 登録日 | 2020-06-09 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
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6ZC7
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6ZC6
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6ZC3
 | | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | | 分子名称: | 1,2-ETHANEDIOL, 5-fluoranyl-2-(methylsulfonylamino)benzoic acid, Dishevelled, ... | | 著者 | Roske, Y, Heinemann, U, Oschkinat, H. | | 登録日 | 2020-06-09 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
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6ZC8
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6ZC4
 | | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | | 分子名称: | 5-bromanyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... | | 著者 | Roske, Y, Heinemann, U, Oschkinat, H. | | 登録日 | 2020-06-09 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
J.Magn.Reson., 2021
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4XH7
 | | Crystal structure of MUPP1 PDZ4 | | 分子名称: | IMIDAZOLE, Multiple PDZ domain protein | | 著者 | Liu, Z, Zhu, H, Liu, W. | | 登録日 | 2015-01-05 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Biochemical and structural characterization of MUPP1-PDZ4 domain from Mus musculus.
Acta Biochim.Biophys.Sin., 47, 2015
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4XHV
 | | Crystal structure of Drosophila Spinophilin-PDZ and a C-terminal peptide of Neurexin | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, LP20995p, ... | | 著者 | Driller, J.H, Muhammad, K.G.H, Reddy, S, Rey, U, Boehme, M.A, Hollmann, C, Ramesh, N, Depner, H, Luetzkendorf, J, Matkovic, T, Bergeron, D, Quentin, C, Schmoranzer, J, Goettfert, F, Holt, M, Wahl, M.C, Hell, S.W, Walter, A, Sigrist, S.J, Loll, B. | | 登録日 | 2015-01-06 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function.
Nat Commun, 6, 2015
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4AMH
 | | Influence of circular permutation on the folding pathway of a PDZ domain | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DISKS LARGE HOMOLOG 1, GLYCEROL | | 著者 | Hultqvist, G, Punekar, A.S, Chi, C.N, Selmer, M, Gianni, S, Jemth, P. | | 登録日 | 2012-03-10 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Tolerance of Protein Folding to a Circular Permutation in a Pdz Domain
Plos One, 7, 2012
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6AK2
 | | Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 | | 分子名称: | Syntenin-1, peptide inhibitor KSL-128018 | | 著者 | Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T. | | 登録日 | 2018-08-29 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | | 主引用文献 | A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
J.Med.Chem., 64, 2021
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6AR4
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4YDP
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4YYX
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4Z8J
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6BJO
 | | PICK1 PDZ domain in complex with the small molecule inhibitor BIO124. | | 分子名称: | (2S)-({4-(4-bromophenyl)-1-[1-(tert-butoxycarbonyl)-L-prolyl]piperidine-4-carbonyl}amino)(cyclopentyl)acetic acid, PRKCA-binding protein | | 著者 | Marcotte, D.J. | | 登録日 | 2017-11-06 | | 公開日 | 2018-01-10 | | 最終更新日 | 2018-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure.
Protein Sci., 27, 2018
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