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5KHU
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Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B.
登録日2016-06-15
公開日2016-09-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
5KHR
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BU of 5khr by Molmil
Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C)
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者VanderLinden, R, Yamaguchi, M, Dube, P, Haselbach, D, Stark, H, Schulman, B.A.
登録日2016-06-15
公開日2016-08-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
5L9U
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BU of 5l9u by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-09-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5L9T
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BU of 5l9t by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-10-26
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5JJT
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BU of 5jjt by Molmil
Crystal structure of a type 5 serine/threonine protein phosphatase from Arabidopsis thaliana
分子名称: NICKEL (II) ION, Serine/threonine-protein phosphatase 5
著者Li, H.M, Pu, H.
登録日2016-04-25
公開日2017-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Crystal structure of a type 5 serine/threonine protein phosphatase from Arabidopsis thaliana
To Be Published
5JHE
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BU of 5jhe by Molmil
The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
分子名称: Peptidyl-prolyl cis-trans isomerase CYP7
著者Yu, Q, Xu, L.
登録日2016-04-20
公開日2017-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
To Be Published
2NC9
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BU of 2nc9 by Molmil
Apo solution structure of Hop TPR2A
分子名称: Stress-induced-phosphoprotein 1
著者Darby, J.F, Vidler, L.R, Simpson, P.J, Matthews, S.J, Sharp, S.Y, Pearl, L.H, Hoelder, S, Workman, P.
登録日2016-03-23
公開日2017-03-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.
Sci Rep, 10, 2020
5G05
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BU of 5g05 by Molmil
Cryo-EM structure of combined apo phosphorylated APC
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
登録日2016-03-16
公開日2016-05-25
最終更新日2019-09-11
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
5G04
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BU of 5g04 by Molmil
Structure of the human APC-Cdc20-Hsl1 complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
登録日2016-03-16
公開日2016-05-25
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation.
Nature, 533, 2016
5FJY
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BU of 5fjy by Molmil
Crystal structure of mouse kinesin light chain 2 (residues 161-480)
分子名称: KINESIN LIGHT CHAIN 2, UNKNOWN PEPTIDE
著者Pernigo, S, Yip, Y.Y, Sanger, A, Xu, M, Dodding, M.P, Steiner, R.A.
登録日2015-10-14
公開日2016-02-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献The Light Chains of Kinesin-1 are Autoinhibited.
Proc.Natl.Acad.Sci.USA, 113, 2016
5A31
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BU of 5a31 by Molmil
Structure of the human APC-Cdh1-Hsl1-UbcH10 complex.
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, Mclaughlin, S.H, Barford, D.
登録日2015-05-26
公開日2015-11-18
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination.
Nature, 522, 2015
4UI9
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BU of 4ui9 by Molmil
Atomic structure of the human Anaphase-Promoting Complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2015-03-27
公開日2015-06-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
4RG7
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BU of 4rg7 by Molmil
Crystal structure of APC3
分子名称: Cell division cycle protein 27 homolog
著者Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
登録日2014-09-29
公開日2014-12-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.25 Å)
主引用文献Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4RG9
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BU of 4rg9 by Molmil
Crystal structure of APC3-APC16 complex (Selenomethionine Derivative)
分子名称: Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog
著者Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
登録日2014-09-29
公開日2014-12-24
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4RG6
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BU of 4rg6 by Molmil
Crystal structure of APC3-APC16 complex
分子名称: Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog
著者Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
登録日2014-09-29
公開日2014-12-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4CGV
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BU of 4cgv by Molmil
First TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD
分子名称: GLYCEROL, HEAT SHOCK PROTEIN HSP 90-ALPHA, RNA POLYMERASE II-ASSOCIATED PROTEIN 3
著者Roe, S.M, Pal, M.
登録日2013-11-26
公開日2014-05-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
4JA9
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BU of 4ja9 by Molmil
Rat PP5 apo
分子名称: MAGNESIUM ION, Serine/threonine-protein phosphatase 5
著者Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K.
登録日2013-02-18
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
4JA7
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BU of 4ja7 by Molmil
Rat PP5 co-crystallized with P5SA-2
分子名称: MAGNESIUM ION, Serine/threonine-protein phosphatase 5
著者Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K.
登録日2013-02-18
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
3ZFW
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BU of 3zfw by Molmil
Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide
分子名称: KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2
著者Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P.
登録日2012-12-12
公開日2013-04-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Kinesin-1:Cargo Recognition.
Science, 340, 2013
4GCO
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BU of 4gco by Molmil
Central domain of stress-induced protein-1 (STI-1) from C.elegans
分子名称: Protein STI-1
著者Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-07-30
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Central domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
4GCN
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BU of 4gcn by Molmil
N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
分子名称: Protein STI-1, TRIETHYLENE GLYCOL
著者Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-07-30
公開日2012-08-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
3VTY
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BU of 3vty by Molmil
Crystal structure of MamA
分子名称: CHLORIDE ION, MamA
著者Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
登録日2012-06-08
公開日2012-10-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
3VTX
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BU of 3vtx by Molmil
Crystal structure of MamA protein
分子名称: GLYCEROL, MamA
著者Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
登録日2012-06-08
公開日2012-10-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
2LNI
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BU of 2lni by Molmil
Solution NMR Structure of Stress-induced-phosphoprotein 1 STI1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4403E
分子名称: Stress-induced-phosphoprotein 1
著者Tang, Y, Liu, G, Hamilton, K, Ciccosanti, C, Shastry, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2011-12-28
公開日2012-03-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target HR4403E
To be Published
3UQ3
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BU of 3uq3 by Molmil
TPR2AB-domain:pHSP90-complex of yeast Sti1
分子名称: Heat shock protein, Heat shock protein STI1
著者Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J.
登録日2011-11-19
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012

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