PDB: 377 件ウェブページステータス検索Chemie searchBIRD

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4V0V	The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-660) 分子名称: MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT, ... 著者 Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. 登録日 2014-09-18 公開日 2015-03-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases. Elife, 4, 2015
5KAS	Murine acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) with phosphocholine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3b, ... 著者 Gorelik, A, Illes, K, Heinz, L.X, Superti-Furga, G, Nagar, B. 登録日 2016-06-02 公開日 2016-10-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.619 Å) 主引用文献 Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. J.Biol.Chem., 291, 2016
3E7A	Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin Nodularin-R 分子名称: AZIDE ION, CHLORIDE ION, GLYCEROL, ... 著者 Kelker, M.S, Page, R, Peti, W. 登録日 2008-08-18 公開日 2008-11-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors J.Mol.Biol., 385, 2009
4B2O	Crystal structure of Bacillus subtilis YmdB, a global regulator of late adaptive responses. 分子名称: FE (II) ION, PHOSPHATE ION, YMDB PHOSPHODIESTERASE 著者 Newman, J.A, Diethmaier, C, Kovacs, A.T, Rodrigues, C, Kuipers, O.P, Stulke, J, Lewis, R.J. 登録日 2012-07-17 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 The Ymdb Phosphodiesterase is a Global Regulator of Late Adaptive Responses in Bacillus Subtilis. J.Bacteriol., 196, 2014
3H67	Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c)with two Zn2+ atoms complexed with cantharidic acid 分子名称: (1R,2S,3R,4S)-2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, Serine/threonine-protein phosphatase 5, ZINC ION 著者 Bertini, I, Calderone, V, Fragai, M, Luchinat, C, Talluri, E. 登録日 2009-04-23 公開日 2009-09-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin J.Med.Chem., 52, 2009
7QWJ	Crystal structure of Glc7 phosphatase 分子名称: MANGANESE (II) ION, PHOSPHATE ION, Serine/threonine-protein phosphatase PP1-2 著者 Malhotra, K, Carminati, M, Bertolotti, A, Bellini, D. 登録日 2022-01-25 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of Glc7 phosphatase To Be Published
3ZK4	Structure of purple acid phosphatase PPD1 isolated from yellow lupin (Lupinus luteus) seeds 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIPHOSPHONUCLEOTIDE PHOSPHATASE 1, ... 著者 Antonyuk, S.V, Strange, R.W. 登録日 2013-01-21 公開日 2014-01-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The Structure of a Purple Acid Phosphatase Involved in Plant Growth and Pathogen Defence Exhibits a Novel Immunoglobulin-Like Fold Iucrj, 1, 2014
5WG8	Structure of PP5C with LB-100; 7-oxabicyclo[2.2.1]heptane-2,3-dicarbonyl moiety modeled in the density 分子名称: (1S,2R,3S,4R)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... 著者 D'Arcy, B.M, Swingle, M.R, Honkanen, R.E, Prakash, A. 登録日 2017-07-13 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C. Mol. Cancer Ther., 18, 2019
5B49	Crystal structure of LpxH with manganese from Pseudomonas aeruginosa 分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, GLYCEROL, MANGANESE (II) ION, ... 著者 Okada, C, Wakabayashi, H, Yao, M, Tanaka, I. 登録日 2016-04-03 公開日 2016-09-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa Sci Rep, 6, 2016
5FC6	Murine SMPDL3A in complex with ADP analog AMPCP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... 著者 Gorelik, A, Illes, K, Superti-Furga, G, Nagar, B. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.658 Å) 主引用文献 Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. J.Biol.Chem., 291, 2016
5FC5	Murine SMPDL3A in complex with phosphocholine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... 著者 Gorelik, A, Illes, K, Superti-Furga, G, Nagar, B. 登録日 2015-12-14 公開日 2016-01-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.678 Å) 主引用文献 Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. J.Biol.Chem., 291, 2016
6GJ2	PURPLE ACID PHYTASE FROM WHEAT ISOFORM B2 - COMPLEX WITH INOSITOL HEXASULPHATE 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Faba-Rodriguez, R, Brearley, C.A, Hemmings, A.M. 登録日 2018-05-15 公開日 2019-11-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structure of a cereal purple acid phytase provides new insights to phytate degradation in plants. Plant Commun., 3, 2022
3E7B	Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin inhibitor Tautomycin 分子名称: (2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10R)-10-{(2S,3S,6R,8S,9R)-3,9-dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undec-2-yl}-3,7-dihydroxy-2-methoxy-6-methyl-1-(1-methylethyl)-5-oxoundecyl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, AZIDE ION, CHLORIDE ION, ... 著者 Kelker, M.S, Page, R, Peti, W. 登録日 2008-08-18 公開日 2008-11-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors J.Mol.Biol., 385, 2009
4F0Z	Crystal Structure of Calcineurin in Complex with the Calcineurin-Inhibiting Domain of the African Swine Fever Virus Protein A238L 分子名称: Ankyrin repeat domain-containing protein A238L, CALCIUM ION, Calcineurin subunit B type 1, ... 著者 Grigoriu, S, Peti, W, Page, R. 登録日 2012-05-05 公開日 2013-03-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. Plos Biol., 11, 2013
4H2B	Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with Baicalin 分子名称: 5'-nucleotidase, 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, CALCIUM ION, ... 著者 Zebisch, M, Pippel, J, Knapp, K, Straeter, N. 登録日 2012-09-12 公開日 2012-11-28 最終更新日 2012-12-26 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling. Structure, 20, 2012
2XMO	The crystal structure of Lmo2642 分子名称: CALCIUM ION, FE (III) ION, LMO2642 PROTEIN, ... 著者 Jeong, J.H, Kim, Y.G. 登録日 2010-07-28 公開日 2011-02-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and Functional Analysis of the Lmo2642 Cyclic Nucleotide Phosphodiesterase from Listeria Monocytogenes. Proteins, 79, 2011
2NXF	Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393 分子名称: ETHANOL, PHOSPHATE ION, Putative dimetal phosphatase, ... 著者 Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-11-17 公開日 2006-12-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393 To be Published
1HP1	5'-NUCLEOTIDASE (OPEN FORM) COMPLEX WITH ATP 分子名称: 5'-NUCLEOTIDASE, ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, ... 著者 Knoefel, T, Straeter, N. 登録日 2000-12-12 公開日 2002-03-20 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanism of hydrolysis of phosphate esters by the dimetal center of 5'-nucleotidase based on crystal structures. J.Mol.Biol., 309, 2001
3IVE	Putative 5'-Nucleotidase (c4898) from Escherichia Coli in complex with Cytidine 分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, CHLORIDE ION, FE (III) ION, ... 著者 Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-08-31 公開日 2009-09-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Putative 5'-Nucleotidase (c4898) from Escherichia Coli in complex with Cytidine To be Published
3TGH	GAP50 the anchor in the inner membrane complex of Plasmodium 分子名称: COBALT (II) ION, DIMETHYL SULFOXIDE, Glideosome-associated protein 50, ... 著者 Bosch, J, Paige, M.H, Vaidya, A, Bergman, L, Hol, W.G.J. 登録日 2011-08-17 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum. J.Struct.Biol., 178, 2012
5B4A	Crystal structure of LpxH with lipid X in spacegroup P21 分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, GLYCEROL, UDP-2,3-diacylglucosamine hydrolase 著者 Okada, C, Wakabayashi, H, Yao, M, Tanaka, I. 登録日 2016-04-03 公開日 2016-09-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa Sci Rep, 6, 2016
7SS7	Crystal structure of Klebsiella LpxH in complex with JH-LPH-50 分子名称: 1,2-ETHANEDIOL, 6-{[(4-{4-[3-chloro-5-(trifluoromethyl)phenyl]piperazine-1-sulfonyl}phenyl)carbamoyl]amino}-N-hydroxyhexanamide, MANGANESE (II) ION, ... 著者 Cho, J, Cochrane, C.S, Zhou, P. 登録日 2021-11-09 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Development of LpxH Inhibitors Chelating the Active Site Dimanganese Metal Cluster of LpxH. Chemmedchem, 18, 2023
1USH	5'-NUCLEOTIDASE FROM E. COLI 分子名称: 5'-NUCLEOTIDASE, CARBONATE ION, SULFATE ION, ... 著者 Knofel, T, Strater, N. 登録日 1998-09-16 公開日 1999-06-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 X-ray structure of the Escherichia coli periplasmic 5'-nucleotidase containing a dimetal catalytic site. Nat.Struct.Biol., 6, 1999
7SS6	Structure of Klebsiella LpxH in complex with JH-LPH-45 分子名称: 1,2-ETHANEDIOL, 5-{4-[3-chloro-5-(trifluoromethyl)phenyl]piperazine-1-sulfonyl}-N-[5-(hydroxyamino)-5-oxopentyl]-2,3-dihydro-1H-indole-1-carboxamide, MANGANESE (II) ION, ... 著者 Cho, J, Cochrane, C.S, Zhou, P. 登録日 2021-11-09 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Development of LpxH Inhibitors Chelating the Active Site Dimanganese Metal Cluster of LpxH. Chemmedchem, 18, 2023
2Z1A	Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8 分子名称: 5'-nucleotidase, PHOSPHATE ION, THYMIDINE, ... 著者 Nakagawa, N, Kishishita, S, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-05-08 公開日 2007-11-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8 To be Published

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