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8PCC
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Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 100 ms
分子名称: BORATE ION, Beta-lactamase, SULFATE ION
著者Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C.
登録日2023-06-11
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
8PCB
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Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 80 ms
分子名称: BORATE ION, Beta-lactamase, SULFATE ION
著者Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C.
登録日2023-06-11
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
8PCA
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Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 50 ms
分子名称: Beta-lactamase, SULFATE ION
著者Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C.
登録日2023-06-11
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
8PC9
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BU of 8pc9 by Molmil
Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 0 ms - native.
分子名称: Beta-lactamase, SULFATE ION
著者Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C.
登録日2023-06-11
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification.
Commun Chem, 7, 2024
8OE5
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BU of 8oe5 by Molmil
Structure of P167S BlaC from Mycobacterium tuberculosis at pH 6.3
分子名称: Beta-lactamase, CITRATE ANION, GLYCEROL
著者Sun, J, Chikunova, A, Ubbink, M.
登録日2023-03-10
公開日2023-08-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
8OE1
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Structure of P167S BlaC from Mycobacterium tuberculosis at pH 5
分子名称: Beta-lactamase, GLYCEROL
著者Sun, J, Chikunova, A, Ubbink, M.
登録日2023-03-10
公開日2023-08-23
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
8KEM
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PKS domains-fused AmpC EC2
分子名称: SDR family NAD(P)-dependent oxidoreductase,Beta-lactamase
著者Son, S.Y, Bae, D.W, Cha, S.S.
登録日2023-08-12
公開日2024-06-05
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (2.76998281 Å)
主引用文献Structural investigation of the docking domain assembly from trans-AT polyketide synthases.
Structure, 32, 2024
8JOI
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BU of 8joi by Molmil
Crystal Structure of Bel-1 E166A Mutant.
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Beta-lactamase, ...
著者Dhankhar, K, Hazra, S.
登録日2023-06-07
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Bel-1 E166A Mutant
To Be Published
8JK3
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Crystal Structure of Bel-1 Extended Spectrum Beta-lactamase in Hexagonal Form
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-lactamase, ...
著者Dhankhar, K, Hazra, S.
登録日2023-05-31
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Bel-1 ESBL in Hexagonal Form
To Be Published
8JB8
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Crystal structure of CMY-185 complex with ceftazidime
分子名称: ACYLATED CEFTAZIDIME, Beta-lactamase
著者Kawai, A, Doi, Y.
登録日2023-05-08
公開日2023-12-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185.
Mbio, 15, 2024
8JB7
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Crystal structure of CMY-185
分子名称: Beta-lactamase, SULFATE ION
著者Kawai, A, Doi, Y.
登録日2023-05-08
公開日2023-12-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185.
Mbio, 15, 2024
8J6Y
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BU of 8j6y by Molmil
Crystal structure of class A beta-lactamase PSE-4 WT- Apo state
分子名称: Beta-lactamase PSE-4, SULFATE ION
著者Sarkar, M, Bhattacharya, S, Hazra, S.
登録日2023-04-26
公開日2024-05-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of class A beta-lactamase PSE-4 WT- Apo state
To be published
8J5V
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BU of 8j5v by Molmil
Crystal structure of estZF172 as a novel biocatalyst for the efficient biosynthesis of a chiral intermediate of pregabalin
分子名称: Carboxylesterase
著者Chi, C.B, Liang, Z.D, Huo, B.Q, Hu, C.X, Sun, Q.Y.
登録日2023-04-24
公開日2024-05-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of estZF172 as a novel biocatalyst for the efficient biosynthesis of a chiral intermediate of pregabalin
To Be Published
8IY4
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BU of 8iy4 by Molmil
Crystal structure of Class A beta-lactamase BlaA WT - complex with Meropenem
分子名称: (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION
著者Bhattacharya, S, Hazra, S.
登録日2023-04-03
公開日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Class A beta-lactamase BlaA WT - complex with Meropenem
To be published
8IXX
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BU of 8ixx by Molmil
Crystal structure of Class A beta-lactamase BlaA WT - complex with Ertapenem
分子名称: (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION
著者Bhattacharya, S, Hazra, S.
登録日2023-04-03
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Class A beta-lactamase BlaA WT - complex with Ertapenem
To be published
8IX8
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Crystal structure of Class A beta-lactamase BlaA WT - complex with Tebipenem
分子名称: (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION
著者Bhattacharya, S, Hazra, S.
登録日2023-03-31
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Class A beta-lactamase BlaA WT - complex with Tebipenem
To be published
8IWV
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BU of 8iwv by Molmil
Crystal structure of BlaA-1 APO
分子名称: Beta-lactamase, PHOSPHATE ION
著者Bhattacharya, S, Hazra, S.
登録日2023-03-31
公開日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of BlaA-1 APO
To be published
8ISR
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BU of 8isr by Molmil
Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by cefaclor
分子名称: (R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-chloro-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase
著者Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S.
登録日2023-03-21
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
8ISQ
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Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by ampicillin
分子名称: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-lactamase, ...
著者Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S.
登録日2023-03-21
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
8ISP
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Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by cephalexin
分子名称: (R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase
著者Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S.
登録日2023-03-21
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
8ISO
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Crystal structure of extended-spectrum class A beta-lactamase, CESS-1
分子名称: 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Beta-lactamase
著者Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S.
登録日2023-03-21
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
8GCX
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XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 700 ms
分子名称: Beta-lactamase, PHOSPHATE ION, TRANS-ENAMINE INTERMEDIATE OF SULBACTAM
著者Malla, T.N, Schmidt, M.
登録日2023-03-03
公開日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam.
Nat Commun, 14, 2023
8GCV
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BU of 8gcv by Molmil
XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals
分子名称: Beta-lactamase, PHOSPHATE ION
著者Malla, T.N, Schmidt, M.
登録日2023-03-03
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam.
Nat Commun, 14, 2023
8GCT
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BU of 8gct by Molmil
XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 6 ms
分子名称: Beta-lactamase, PHOSPHATE ION
著者Malla, T.N, Schmidt, M.
登録日2023-03-03
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam.
Nat Commun, 14, 2023
8GCS
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BU of 8gcs by Molmil
XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 3 ms
分子名称: Beta-lactamase, PHOSPHATE ION
著者Malla, T.N, Schmidt, M.
登録日2023-03-03
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam.
Nat Commun, 14, 2023

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件を2024-10-09に公開中

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