8JB7

Crystal structure of CMY-185

Summary for 8JB7

• Entry DOI: 10.2210/pdb8jb7/pdb
• Descriptor: Beta-lactamase, SULFATE ION (3 entities in total)
• Functional Keywords: beta-lactamase, cmy-2-like, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 80155.41

Authors

Kawai, A.,Doi, Y. (deposition date: 2023-05-08, release date: 2023-12-13, Last modification date: 2024-02-28)

• Primary citation: Kawai, A.,Shropshire, W.C.,Suzuki, M.,Borjan, J.,Aitken, S.L.,Bachman, W.C.,McElheny, C.L.,Bhatti, M.M.,Shields, R.K.,Shelburne, S.A.,Doi, Y.; Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185.; Mbio, 15:e0287423-e0287423, 2024; PubMed: 38179965; DOI: 10.1128/mbio.02874-23

Experimental method

X-RAY DIFFRACTION (1.35 Å)