PDB: 367 件ウェブページステータス検索Chemie searchBIRD

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4YAI	Crystal structure of LigL in complex with NADH and GGE from Sphingobium sp. strain SYK-6 分子名称: (1S,2R)-1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C alpha-dehydrogenase, ... 著者 Pereira, J.H, McAndrew, R.P, Heins, R.A, Sale, K.L, Simmons, B.A, Adams, P.D. 登録日 2015-02-17 公開日 2016-03-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural and Biochemical Characterization of the Early and Late Enzymes in the Lignin beta-Aryl Ether Cleavage Pathway from Sphingobium sp. SYK-6. J.Biol.Chem., 291, 2016
3TJR	Crystal structure of a Rv0851c ortholog short chain dehydrogenase from Mycobacterium paratuberculosis 分子名称: UNKNOWN LIGAND, short chain dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-08-24 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4YAE	Crystal structure of LigL-apo form from Sphingobium sp. strain SYK-6 分子名称: C alpha-dehydrogenase 著者 Pereira, J.H, McAndrew, R.P, Heins, R.A, Sale, K.L, Simmons, B.A, Adams, P.D. 登録日 2015-02-17 公開日 2016-03-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Structural and Biochemical Characterization of the Early and Late Enzymes in the Lignin beta-Aryl Ether Cleavage Pathway from Sphingobium sp. SYK-6. J.Biol.Chem., 291, 2016
6I6P	SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 3 分子名称: 1,2-ETHANEDIOL, 6-azaspiro[3.4]octan-6-yl-[2,4-bis(chloranyl)-6-oxidanyl-phenyl]methanone, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Alen, J, Schade, M, Wagener, M, Blaesse, M. 登録日 2018-11-15 公開日 2019-07-10 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors. J.Med.Chem., 62, 2019
6I79	SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 4 分子名称: 6-[(4-~{tert}-butyl-1,3-thiazol-2-yl)methyl]-4,6-diazaspiro[2.4]heptane-5,7-dione, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase 著者 Alen, J, Schade, M, Wagener, M, Blaesse, M. 登録日 2018-11-16 公開日 2019-07-10 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors. J.Med.Chem., 62, 2019
1QYW	Crystal structure of human estrogenic 17beta-hydroxysteroid dehydrogenase complex with androstanedione and NADP 分子名称: 5ALPHA-ANDROSTAN-3,17-DIONE, Estradiol 17 beta-dehydrogenase 1, GLYCEROL, ... 著者 Shi, R, Lin, S.X. 登録日 2003-09-12 公開日 2004-08-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation. J.Biol.Chem., 279, 2004
1MG5	Crystal structure of Drosophila melanogaster alcohol dehydrogenase complexed with NADH and acetate at 1.6 A 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ACETATE ION, alcohol dehydrogenase 著者 Benach, J, Atrian, S, Gonzalez-Duarte, R, Ladenstein, R. 登録日 2002-08-14 公開日 2003-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Drosophila alcohol dehydrogenase: acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis J.Mol.Biol., 345, 2005
8AEQ	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal R773Q variant 分子名称: Short-chain dehydrogenase/reductase SDR 著者 Kabasakal, B.V, Murray, J.W. 登録日 2022-07-13 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
4XGN	Crystal structure of 3-hydroxyacyl-CoA dehydrogenase in complex with NAD from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-12-31 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of 3-hydroxyacyl-CoA dehydrogenase in complex with NAD from Burkholderia thailandensis to be published
4N5L	Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha 分子名称: Acetoacetyl-CoA reductase 著者 Kim, J.-E, Kim, S, Kim, K.-J. 登録日 2013-10-10 公開日 2013-12-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha Biochem.Biophys.Res.Commun., 443, 2014
1OOE	Structural Genomics of Caenorhabditis elegans : Dihydropteridine reductase 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dihydropteridine reductase 著者 Symersky, J, Li, S, Nagy, L, Qiu, S, Lin, G, Tsao, J, Luo, D, Carson, M, DeLucas, L, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG) 登録日 2003-03-03 公開日 2003-03-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural genomics of Caenorhabditis elegans: structure of dihydropteridine reductase. Proteins, 53, 2003
5IF3	Crystal structure of a Short-chain dehydrogenase/reductase SDR from Burkholderia vietnamiensis 分子名称: Short-chain dehydrogenase/reductase SDR 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of a Short-chain dehydrogenase/reductase SDR from Burkholderia vietnamiensis to be published
5TQV	Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans 分子名称: NADPH-dependent carbonyl reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-10-24 公開日 2016-11-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans TO BE PUBLISHED
5U9P	Crystal structure of a gluconate 5-dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP and tartrate 分子名称: 1,2-ETHANEDIOL, Gluconate 5-dehydrogenase, L(+)-TARTARIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-12-17 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of a gluconate 5-dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP and tartrate TO BE PUBLISHED
2GDZ	Crystal structure of 15-hydroxyprostaglandin dehydrogenase type1, complexed with NAD+ 分子名称: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Pilka, E.S, Guo, K, Kavanagh, K, Von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2006-03-17 公開日 2006-04-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 High-Affinity Inhibitors of Human NAD-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships. Plos One, 5, 2010
3WTC	Crystal structure of Gox2036 分子名称: Putative oxidoreductase 著者 Yuan, Y.A, Lin, J.P. 登録日 2014-04-09 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of Gox0525 To be Published
3TN7	Crystal structure of short-chain alcohol dehydrogenase from hyperthermophilic archaeon Thermococcus sibiricus complexed with 5-hydroxy-NADP 分子名称: 5-hydroxy-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, Short-chain alcohol dehydrogenase 著者 Boyko, K.M, Polyakov, K.M, Bezsudnova, E.Y, Stekhanova, T.N, Gumerov, V.M, Mardanov, A.V, Ravin, N.V, Skryabin, K.G, Kovalchuk, M.V, Popov, V.O. 登録日 2011-09-01 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structural insight into the molecular basis of polyextremophilicity of short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Thermococcus sibiricus. Biochimie, 94, 2012
1FJH	THE CRYSTAL STRUCTURE OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY 分子名称: 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE 著者 Grimm, C, Ficner, R, Maser, E, Klebe, G, Reuter, K. 登録日 2000-08-08 公開日 2001-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family. J.Biol.Chem., 275, 2000
4KZP	Crystal Structure of a Putative Short Chain Dehydrogenase from Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Oxidoreductase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-05-30 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal Structure of a Putative Short Chain Dehydrogenase from Mycobacterium smegmatis To be Published
3E03	Crystal structure of a putative dehydrogenase from Xanthomonas campestris 分子名称: CALCIUM ION, Short chain dehydrogenase 著者 Sampathkumar, P, Wasserman, S, Rutter, M, Hu, S, Bain, K, Rodgers, L, Atwell, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2008-07-30 公開日 2008-09-16 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal structure of a putative dehydrogenase from Xanthomonas campestris To be Published
4YAC	Crystal structure of LigO in complex with NADH from Sphingobium sp. strain SYK-6 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, C alpha-dehydrogenase 著者 Pereira, J.H, McAndrew, R.P, Heins, R.A, Sale, K.L, Simmons, B.A, Adams, P.D. 登録日 2015-02-17 公開日 2016-03-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Structural and Biochemical Characterization of the Early and Late Enzymes in the Lignin beta-Aryl Ether Cleavage Pathway from Sphingobium sp. SYK-6. J.Biol.Chem., 291, 2016
3DEY	Crystal structure of 17beta-HSD1 with DHT in normal and reverse orientation. 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Estradiol 17-beta-dehydrogenase 1, GLYCEROL 著者 Mazumdar, M. 登録日 2008-06-10 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 17beta-HSD1 stimulates breast cancer by DHT inactivation in addition to estradiol production. To be Published
3KLM	17beta-HSD1 in complex with DHT 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Estradiol 17-beta-dehydrogenase 1, GLYCEROL 著者 Mazumdar, M. 登録日 2009-11-08 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Mol.Endocrinol., 24, 2010
3E9Q	Crystal Structure of the Short Chain Dehydrogenase from Shigella flexneri 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... 著者 Kim, Y, Xu, X, Cui, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2008-08-23 公開日 2008-09-23 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of the Short Chain Dehydrogenase from Shigella flexneri To be Published
1FDS	HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 COMPLEXED WITH 17-BETA-ESTRADIOL 分子名称: 17-BETA-HYDROXYSTEROID-DEHYDROGENASE, ESTRADIOL 著者 Housset, D, Breton, R, Mazza, C, Fontecilla-Camps, J.-C. 登録日 1996-06-28 公開日 1997-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors. Structure, 4, 1996

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