3DEY

Crystal structure of 17beta-HSD1 with DHT in normal and reverse orientation.

Summary for 3DEY

• Entry DOI: 10.2210/pdb3dey/pdb
• Descriptor: Estradiol 17-beta-dehydrogenase 1, 5-ALPHA-DIHYDROTESTOSTERONE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: 17beta-hsd1, dht, lipid synthesis, nadp, oxidoreductase, steroid biosynthesis
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P14061
• Total number of polymer chains: 1
• Total formula weight: 35270.36

Authors

Mazumdar, M. (deposition date: 2008-06-10, release date: 2009-09-29, Last modification date: 2024-02-21)

• Primary citation: Mazumdar, M.,Aka, J.,Poirier, D.,Lin, S.-X.; 17beta-HSD1 stimulates breast cancer by DHT inactivation in addition to estradiol production.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)