3TN7

Crystal structure of short-chain alcohol dehydrogenase from hyperthermophilic archaeon Thermococcus sibiricus complexed with 5-hydroxy-NADP

Summary for 3TN7

Entry DOI	10.2210/pdb3tn7/pdb
Descriptor	Short-chain alcohol dehydrogenase, 5-hydroxy-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (4 entities in total)
Functional Keywords	nadp-dependent dehydrogenase, short-chain dehydrogenase, 5-hydroxy-nadp, thermophile, archaea, rossmann fold, oxidation of alcohols and reductions of ketones and aldehydes, oxidoreductase
Biological source	Thermococcus sibiricus
Total number of polymer chains	2
Total formula weight	59080.81
Authors	Boyko, K.M.,Polyakov, K.M.,Bezsudnova, E.Y.,Stekhanova, T.N.,Gumerov, V.M.,Mardanov, A.V.,Ravin, N.V.,Skryabin, K.G.,Kovalchuk, M.V.,Popov, V.O. (deposition date: 2011-09-01, release date: 2012-08-15, Last modification date: 2023-09-13)
Primary citation	Bezsudnova, E.Y.,Boyko, K.M.,Polyakov, K.M.,Dorovatovskiy, P.V.,Stekhanova, T.N.,Gumerov, V.M.,Ravin, N.V.,Skryabin, K.G.,Kovalchuk, M.V.,Popov, V.O. Structural insight into the molecular basis of polyextremophilicity of short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Thermococcus sibiricus. Biochimie, 94:2628-2638, 2012 Cited by PubMed: 22885278 DOI: 10.1016/j.biochi.2012.07.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.68 Å)

Structure validation