3TN7

Crystal structure of short-chain alcohol dehydrogenase from hyperthermophilic archaeon Thermococcus sibiricus complexed with 5-hydroxy-NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Short-chain alcohol dehydrogenase	polymer	257	28733.9	2	UniProt (C6A190) Pfam (PF00106)	Thermococcus sibiricus
2	C, E (A, B)	5-hydroxy-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		760.4	2	Chemie (NJP)
3	D (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	F, G (A, B)	water	water		18.0	294	Chemie (HOH)

Sequence modifications

A, B: 1 - 234 (UniProt: C6A190)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Leu -1	-	expression tag
Glu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57467.9
Non-Polymers*	Number of molecules	3
	Total formula weight	1612.9
All*	Total formula weight	59080.8

*Water molecules are not included.