5DUQ
 
 | | Active human c1-inhibitor in complex with dextran sulfate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma protease C1 inhibitor, SULFITE ION, ... | | 著者 | Dijk, M, Holkers, J, Voskamp, P, Giannetti, B.M, Waterreus, W.J, van Veen, H.A, Pannu, N.S. | | 登録日 | 2015-09-20 | | 公開日 | 2016-08-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation.
Structure, 24, 2016
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5EI0
 | | Structure of RCL-cleaved vaspin (serpinA12) | | 分子名称: | Serpin A12 | | 著者 | Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N. | | 登録日 | 2015-10-29 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of cleaved vaspin (serpinA12).
Biol.Chem., 397, 2016
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2OAY
 | | Crystal structure of latent human C1-inhibitor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Plasma protease C1 inhibitor | | 著者 | Harmat, V, Beinrohr, L, Gal, P, Dobo, J. | | 登録日 | 2006-12-18 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease
J.Biol.Chem., 282, 2007
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2OL2
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2PEE
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State | | 分子名称: | GLYCEROL, SULFATE ION, Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-02 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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2PEF
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State | | 分子名称: | Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-03 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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1WZ9
 | | The 2.1 A structure of a tumour suppressing serpin | | 分子名称: | Maspin precursor, SULFATE ION | | 著者 | Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. | | 登録日 | 2005-03-03 | | 公開日 | 2005-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
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4R9I
 | | Crystal structure of cysteine proteinase inhibitor Serpin18 from Bombyx mori | | 分子名称: | BETA-MERCAPTOETHANOL, CITRATE ANION, SODIUM ION, ... | | 著者 | Guo, P.C, He, H.W, Zhao, P, Xia, Q.Y. | | 登録日 | 2014-09-05 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18
Sci Rep, 5, 2015
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4G8R
 | | Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 | | 分子名称: | (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION | | 著者 | Stuckey, J.A, Lawrence, D.A, Li, S.-H. | | 登録日 | 2012-07-23 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4G8O
 | | Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 | | 分子名称: | (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ... | | 著者 | Stuckey, J.A, Lawrence, D.A, Li, S.-H. | | 登録日 | 2012-07-23 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4ZK0
 | | Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure | | 分子名称: | Serpin B4, ZINC ION | | 著者 | Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J. | | 登録日 | 2015-04-29 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates.
Biochem Biophys Rep, 2, 2015
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4GA7
 | | Crystal structure of human serpinB1 mutant | | 分子名称: | Leukocyte elastase inhibitor | | 著者 | Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. | | 登録日 | 2012-07-25 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
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4ZK3
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4RSQ
 | | 2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-11-10 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
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4Y40
 | | Structure of Vaspin mutant D305C V383C | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Serpin A12 | | 著者 | Pippel, J, Strater, N, Ulbricht, D, Schultz, S, Meier, R, Heiker, J.T. | | 登録日 | 2015-02-10 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin).
Biochem.J., 470, 2015
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4ROA
 | | 1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
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4RO9
 | | 2.0A resolution structure of SRPN2 (S358E) from Anopheles gambiae | | 分子名称: | GLYCEROL, Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
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4ROB
 | | 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae
To be Published
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4YIA
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3F5N
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3FGQ
 | | Crystal structure of native human neuroserpin | | 分子名称: | GLYCEROL, Neuroserpin | | 著者 | Takehara, S, Yang, X, Mikami, B, Onda, M. | | 登録日 | 2008-12-08 | | 公開日 | 2009-04-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability
J.Mol.Biol., 388, 2009
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4EB1
 | | Hyperstable in-frame insertion variant of antithrombin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III | | 著者 | Martinez-Martinez, I, Johnson, D.J.D, Yamasaki, M, Corral, J, Huntington, J.A. | | 登録日 | 2012-03-23 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance.
J.Thromb.Haemost., 10, 2012
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1XU8
 | | The 2.8 A structure of a tumour suppressing serpin | | 分子名称: | Maspin, SULFATE ION | | 著者 | Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C. | | 登録日 | 2004-10-25 | | 公開日 | 2005-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
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1XQG
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1XQJ
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