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7RBW
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Structure of Biliverdin-binding Serpin of Boana punctata (polka-dot tree frog)
分子名称: BILIVERDINE IX ALPHA, Biliverdin bindin serpin
著者Fedorov, E, Manoilov, K.Y, Verkhusha, V, Almo, S.C, Ghosh, A.
登録日2021-07-06
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and Functional Characterization of a Biliverdin-Binding Near-Infrared Fluorescent Protein From the Serpin Superfamily.
J.Mol.Biol., 434, 2021
5EI0
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BU of 5ei0 by Molmil
Structure of RCL-cleaved vaspin (serpinA12)
分子名称: Serpin A12
著者Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N.
登録日2015-10-29
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of cleaved vaspin (serpinA12).
Biol.Chem., 397, 2016
2OAY
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BU of 2oay by Molmil
Crystal structure of latent human C1-inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Plasma protease C1 inhibitor
著者Harmat, V, Beinrohr, L, Gal, P, Dobo, J.
登録日2006-12-18
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease
J.Biol.Chem., 282, 2007
5DUQ
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Active human c1-inhibitor in complex with dextran sulfate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma protease C1 inhibitor, SULFITE ION, ...
著者Dijk, M, Holkers, J, Voskamp, P, Giannetti, B.M, Waterreus, W.J, van Veen, H.A, Pannu, N.S.
登録日2015-09-20
公開日2016-08-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation.
Structure, 24, 2016
2PEE
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BU of 2pee by Molmil
Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State
分子名称: GLYCEROL, SULFATE ION, Serine protease inhibitor
著者Zhang, Q.W, Buckle, A.M, Whisstock, J.C.
登録日2007-04-02
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
2OL2
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BU of 2ol2 by Molmil
High Resolution Structure of Native PCI in Space Group P21
分子名称: GLYCEROL, Plasma serine protease inhibitor
著者Li, W, Huntington, J.A.
登録日2007-01-18
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
2PEF
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BU of 2pef by Molmil
Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State
分子名称: Serine protease inhibitor
著者Zhang, Q.W, Buckle, A.M, Whisstock, J.C.
登録日2007-04-03
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
5C98
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1.45A resolution structure of SRPN18 from Anopheles gambiae
分子名称: AGAP007691-PB
著者Lovell, S, Battaile, K.P, Gulley, M, Zhang, X, Meekins, D.A, Gao, F.P, Michel, K.
登録日2015-06-26
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献1.45 angstrom resolution structure of SRPN18 from the malaria vector Anopheles gambiae.
Acta Crystallogr F Struct Biol Commun, 72, 2016
4R9I
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Crystal structure of cysteine proteinase inhibitor Serpin18 from Bombyx mori
分子名称: BETA-MERCAPTOETHANOL, CITRATE ANION, SODIUM ION, ...
著者Guo, P.C, He, H.W, Zhao, P, Xia, Q.Y.
登録日2014-09-05
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18
Sci Rep, 5, 2015
2H4R
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BU of 2h4r by Molmil
Crystal structure of wildtype MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S.
登録日2006-05-25
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
4G8R
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BU of 4g8r by Molmil
Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1
分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION
著者Stuckey, J.A, Lawrence, D.A, Li, S.-H.
登録日2012-07-23
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4G8O
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Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1
分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ...
著者Stuckey, J.A, Lawrence, D.A, Li, S.-H.
登録日2012-07-23
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GA7
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BU of 4ga7 by Molmil
Crystal structure of human serpinB1 mutant
分子名称: Leukocyte elastase inhibitor
著者Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z.
登録日2012-07-25
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
2HI9
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BU of 2hi9 by Molmil
Crystal Structure of human native protein C inhibitor
分子名称: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor
著者Li, W, Adams, T.E, Huntington, J.A.
登録日2006-06-29
公開日2007-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
2HIJ
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Crystal Structure of P14 Alanine Variant of Antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
著者Luis, S.A, Bock, S.C, Huntington, J.A.
登録日2006-06-29
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of P14 Alanine Variant of Antithrombin
To be Published
1YXA
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Serpina3n, a murine orthologue of human antichymotrypsin
分子名称: serine (or cysteine) proteinase inhibitor, clade A, member 3N
著者Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C.
登録日2005-02-20
公開日2005-09-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.
J.Biol.Chem., 280, 2005
1XQG
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3.10 A crystal structure of maspin, Space group P 4 21 2
分子名称: Maspin
著者Al-Ayyoubi, M, Gettins, P.G, Volz, K.
登録日2004-10-12
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained
J.Biol.Chem., 279, 2004
1XQJ
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3.10 A Crystal structure of maspin, space group I 4 2 2
分子名称: Maspin
著者Al-Ayyoubi, M, Gettins, P.G, Volz, K.
登録日2004-10-12
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained
J.Biol.Chem., 279, 2004
4IC0
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BU of 4ic0 by Molmil
Crystal Structure of PAI-1 in Complex with Gallate
分子名称: 3,4,5-trihydroxybenzoic acid, Plasminogen activator inhibitor 1
著者Hong, Z.B, Lin, Z.H, Gong, L.H, Huang, M.D.
登録日2012-12-09
公開日2013-12-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal Structure of PAI-1 in Complex with Gallate
To be Published
2ACH
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BU of 2ach by Molmil
CRYSTAL STRUCTURE OF CLEAVED HUMAN ALPHA1-ANTICHYMOTRYPSIN AT 2.7 ANGSTROMS RESOLUTION AND ITS COMPARISON WITH OTHER SERPINS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA 1-ANTICHYMOTRYPSIN, PHOSPHATE ION, ...
著者Baumann, U, Huber, R, Bode, W, Grosse, D, Lesjak, M, Laurell, C.B.
登録日1993-04-26
公開日1993-07-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins.
J.Mol.Biol., 218, 1991
2H4Q
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BU of 2h4q by Molmil
Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation
分子名称: Heterochromatin-associated protein MENT
著者Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
登録日2006-05-25
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2H4P
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BU of 2h4p by Molmil
Crystal structure of wildtype MENT in the cleaved conformation
分子名称: Heterochromatin-associated protein MENT
著者Buckle, A.M, McGowan, S, Irving, J.A, Whisstock, J.C.
登録日2006-05-24
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
4IF8
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BU of 4if8 by Molmil
Structure Of Vaspin
分子名称: SULFATE ION, Serpin A12
著者Kuettner, E.B, Strater, N, Heiker, J.T, Kloting, N, Kovacs, P, Schultz, S, Kern, M, Stumvoll, M, Bluher, M, Beck-Sickinger, A.G.
登録日2012-12-14
公開日2013-02-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Vaspin inhibits kallikrein 7 by serpin mechanism
Cell.Mol.Life Sci., 70, 2013
1XU8
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The 2.8 A structure of a tumour suppressing serpin
分子名称: Maspin, SULFATE ION
著者Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C.
登録日2004-10-25
公開日2005-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
1SEK
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THE STRUCTURE OF ACTIVE SERPIN K FROM MANDUCA SEXTA AND A MODEL FOR SERPIN-PROTEASE COMPLEX FORMATION
分子名称: SERPIN K
著者Li, J, Wang, Z, Canagarajah, B, Jiang, H, Kanost, M, Goldsmith, E.J.
登録日1998-03-06
公開日1999-03-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of active serpin 1K from Manduca sexta.
Structure Fold.Des., 7, 1999

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