7KOG
| Lethocerus Myosin II complete coiled-coil domain resolved in its native environment | 分子名称: | Myosin heavy chain isoform Mhc_X1 | 著者 | Rahmani, H, Hu, Z, Daneshparvar, N, Taylor, D, Taylor, K.A. | 登録日 | 2020-11-09 | 公開日 | 2021-03-24 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | The myosin II coiled-coil domain atomic structure in its native environment. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
2MYS
| |
2OS8
| Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor | 分子名称: | CALCIUM ION, MAGNESIUM ION, Myosin essential light chain, ... | 著者 | Yang, Y, Gourinath, S, Cohen, C, Brown, J.H. | 登録日 | 2007-02-05 | 公開日 | 2007-05-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | 主引用文献 | Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor. Structure, 15, 2007
|
|
6YSY
| Skeletal Myosin bound to MPH-220, MgADP-VO4 | 分子名称: | (9~{S})-5-methyl-12-(4-morpholin-4-ylphenyl)-9-oxidanyl-4-thia-2,12-diazatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),5-trien-8-one, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Canon, L, Kikuti, C.M, Gyimesi, M, Malnasi-Csizmadia, A, Houdusse, A. | 登録日 | 2020-04-23 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.246 Å) | 主引用文献 | Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness. Cell, 183, 2020
|
|
1MMN
| X-RAY STRUCTURES OF THE MGADP, MGATPGAMMAS, AND MGAMPPNP COMPLEXES OF THE DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN | 分子名称: | MAGNESIUM ION, MYOSIN, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Gulick, A.M, Bauer, C.B, Thoden, J.B, Rayment, I. | 登録日 | 1997-07-18 | 公開日 | 1997-12-03 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain. Biochemistry, 36, 1997
|
|
1MNE
| |
1MND
| |
1MMD
| TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-BEF3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Fisher, A.J, Holden, H.M, Rayment, I. | 登録日 | 1995-03-21 | 公開日 | 1996-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry, 34, 1995
|
|
6Z2S
| Crystal structure of adhibin analogue-bound myosin-2 | 分子名称: | 3,6-dibromo-1-(hydroxymethyl)carbazole, ACETATE ION, ADP METAVANADATE, ... | 著者 | Ewert, W, Knoelker, H.-J, Tsiavaliaris, G, Preller, M. | 登録日 | 2020-05-18 | 公開日 | 2021-06-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The synthetic carbazole adhibin acts as selective myosin class-IX inhibitor in lung cancer cells To Be Published
|
|
7QIO
| Homology model of myosin neck domain in skeletal sarcomere | 分子名称: | Myosin light chain 1/3, skeletal muscle isoform, Myosin regulatory light chain 2, ... | 著者 | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | 登録日 | 2021-12-15 | 公開日 | 2022-02-16 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science, 375, 2022
|
|
2BKH
| Myosin VI nucleotide-free (MDInsert2) crystal structure | 分子名称: | CALCIUM ION, CALMODULIN, GLYCEROL, ... | 著者 | Menetrey, J, Bahloul, A, Yengo, C, Wells, A, Morris, C, Sweeney, H.L, Houdusse, A. | 登録日 | 2005-02-16 | 公開日 | 2005-06-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Structure of the Myosin Vi Motor Reveals the Mechanism of Directionality Reversal Nature, 435, 2005
|
|
7B1A
| Myosin-II-AA mutant motor domain | 分子名称: | 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ... | 著者 | Ewert, W, Preller, M. | 登録日 | 2020-11-24 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release. Int J Mol Sci, 22, 2020
|
|
7B19
| Mutant Myosin-II-GGG motor domain | 分子名称: | ADP METAVANADATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Ewert, W, Preller, M. | 登録日 | 2020-11-24 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release. Int J Mol Sci, 22, 2020
|
|
2BKI
| Myosin VI nucleotide-free (MDinsert2-IQ) crystal structure | 分子名称: | CALCIUM ION, CALMODULIN, SULFATE ION, ... | 著者 | Menetrey, J, Bahloul, A, Yengo, C, Wells, A, Morris, C, Sweeney, H.L, Houdusse, A. | 登録日 | 2005-02-16 | 公開日 | 2005-06-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The Structure of the Myosin Vi Motor Reveals the Mechanism of Directionality Reversal Nature, 435, 2005
|
|
2EC6
| Placopecten Striated Muscle Myosin II | 分子名称: | CALCIUM ION, Myosin essential light chain, Myosin heavy chain, ... | 著者 | Yang, Y, Brown, J, Samudrala, G, Reutzel, R, Szent-Gyorgyi, A. | 登録日 | 2007-02-10 | 公開日 | 2008-02-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure, 15, 2007
|
|
4AE3
| Crystal structure of ammosamide 272:myosin-2 motor domain complex | 分子名称: | 1,2-ETHANEDIOL, ADP ORTHOVANADATE, AMMOSAMIDE 272, ... | 著者 | Chinthalapudi, K, Heissler, S.M, Fenical, W, Manstein, D.J. | 登録日 | 2012-01-05 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Ammosamide Mediated Myosin Motor Activity Inhibition To be Published
|
|
2AKA
| Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus | 分子名称: | Dynamin-1, LINKER, myosin II heavy chain | 著者 | Reubold, T.F, Eschenburg, S, Becker, A, Leonard, M, Schmid, S.L, Vallee, R.B, Kull, F.J, Manstein, D.J. | 登録日 | 2005-08-03 | 公開日 | 2005-08-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the GTPase domain of rat dynamin 1. Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
4ANJ
| MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CALMODULIN, ... | 著者 | Menetrey, J, Isabet, T, Ropars, V, Mukherjea, M, Pylypenko, O, Liu, X, Perez, J, Vachette, P, Sweeney, H.L, Houdusse, A.M. | 登録日 | 2012-03-19 | 公開日 | 2012-10-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi. Mol.Cell, 48, 2012
|
|
2DFS
| 3-D structure of Myosin-V inhibited state | 分子名称: | Calmodulin, Myosin-5A | 著者 | Liu, J, Taylor, D.W, Krementsova, E.B, Trybus, K.M, Taylor, K.A. | 登録日 | 2006-03-03 | 公開日 | 2006-04-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (24 Å) | 主引用文献 | Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography Nature, 442, 2006
|
|
8CDM
| Plasmodium falciparum Myosin A full-length, post-rigor state complexed to the inhibitor KNX-002 | 分子名称: | 1,2-ETHANEDIOL, 1-(4-methoxyphenyl)-~{N}-[(3-thiophen-2-yl-1~{H}-pyrazol-4-yl)methyl]cyclopropan-1-amine, Myosin A tail domain interacting protein, ... | 著者 | Moussaoui, D, Robblee, J.P, Robert-Paganin, J, Auguin, D, Fisher, F, Fagnant, P.M, MacFarlane, J.E, Mueller-Dieckmann, C, Baum, J, Trybus, K.M, Houdusse, A. | 登録日 | 2023-01-31 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Plasmodium falciparum Myosin A full-length, post-rigor state complexed to the inhibitor KNX-002 To Be Published
|
|
2Y8I
| Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN-2 HEAVY CHAIN | 著者 | Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. | 登録日 | 2011-02-07 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.132 Å) | 主引用文献 | Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
|
|
2XO8
| Crystal Structure of Myosin-2 in Complex with Tribromodichloropseudilin | 分子名称: | 2,4-DICHLORO-6-(3,4,5-TRIBROMO-1H-PYRROL-2-YL)PHENOL, ADP METAVANADATE, MAGNESIUM ION, ... | 著者 | Preller, M, Chinthalapudi, K, Martin, R, Knoelker, H.J, Manstein, D.J. | 登録日 | 2010-08-10 | 公開日 | 2011-05-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inhibition of Myosin ATPase Activity by Halogenated Pseudilins: A Structure-Activity Study. J.Med.Chem., 54, 2011
|
|
8U95
| The structure of myosin heavy chain from Drosophila melanogaster flight muscle thick filaments | 分子名称: | Myosin heavy chain, isoform U | 著者 | Abbasi Yeganeh, F, Rastegarpouyani, H, Li, J, Taylor, K.A. | 登録日 | 2023-09-18 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structure of the Drosophila melanogaster Flight Muscle Myosin Filament at 4.7 angstrom Resolution Reveals New Details of Non-Myosin Proteins. Int J Mol Sci, 24, 2023
|
|
8EFE
| Human beta-cardiac myosin II bound to ADP-MG2+ and the associated essential light chain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beta-cardiac myosin II, MAGNESIUM ION, ... | 著者 | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | 登録日 | 2022-09-08 | 公開日 | 2023-01-11 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. J.Gen.Physiol., 155, 2023
|
|
8EFD
| |