5N6A

Cardiac muscle myosin motor domain in the pre-powerstroke state

Summary for 5N6A

Entry DOI	10.2210/pdb5n6a/pdb
Descriptor	Myosin-7, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	myosin, cardiac, pre-powerstroke, motor protein
Biological source	Bos taurus (cattle)
Cellular location	Cytoplasm, myofibril : Q9BE39
Total number of polymer chains	1
Total formula weight	95431.23
Authors	Planelles-Herrero, V.J.,Hartman, J.J.,Robert-Paganin, J.,Malik, F.I.,Houdusse, A. (deposition date: 2017-02-14, release date: 2017-08-09, Last modification date: 2024-01-17)
Primary citation	Planelles-Herrero, V.J.,Hartman, J.J.,Robert-Paganin, J.,Malik, F.I.,Houdusse, A. Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil. Nat Commun, 8:190-190, 2017 Cited by PubMed: 28775348 DOI: 10.1038/s41467-017-00176-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation