2Y8I

Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2

Summary for 2Y8I

Related1MNE 1D1C 1W9L 1VOM 1MMN 2AKA 2JHR 1W9J 2X9H 1FMV 1MMA 2XO8 1MMG 1W9I 1W9K 1MND 1JX2 1Q5G 1D0Y 2XEL 2JJ9 1LVK 1JWY 1YV3 1FMW 1D0X 1D1B 1G8X 1D1A 1D0Z 1MMD 2Y0R 2Y9E
DescriptorMYOSIN-2 HEAVY CHAIN, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsmotor protein, adp complex
Biological sourceDICTYOSTELIUM DISCOIDEUM (SLIME MOLD)
Total number of polymer chains1
Total molecular weight86831.21
Authors
Preller, M.,Bauer, S.,Adamek, N.,Fujita-Becker, S.,Fedorov, R.,Geeves, M.A.,Manstein, D.J. (deposition date: 2011-02-07, release date: 2011-07-20, Last modification date: 2019-07-31)
Primary citation
Preller, M.,Bauer, S.,Adamek, N.,Fujita-Becker, S.,Fedorov, R.,Geeves, M.A.,Manstein, D.J.
Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V.
J.Biol.Chem., 286:35051-, 2011
PubMed: 21841195 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M111.265298
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.132 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers 0.347111 3.3% 2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution