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6PWR
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Crystal structure of the cow C-type carbohydrate-recognition domain of CD23 in the presence of GlcNAc-beta1-2-Man
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, CALCIUM ION, Fc fragment of IgE receptor II
著者Weis, W.I, Feinberg, H.
登録日2019-07-23
公開日2019-09-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献CD23 is a glycan-binding receptor in some mammalian species.
J.Biol.Chem., 294, 2019
2XR6
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Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo trimannoside mimic.
分子名称: 2-AZIDOETHANOL, CALCIUM ION, CD209 ANTIGEN, ...
著者Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F.
登録日2010-09-10
公開日2011-10-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Unique Dc-Sign Clustering Activity of a Small Glycomimetic: A Lesson for Ligand Design.
Acs Chem.Biol., 9, 2014
7XMP
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High resolution structure of lectin-like Ox-LDL receptor 1 in space group P 32 2 1
分子名称: Oxidized low-density lipoprotein receptor 1
著者Tomar, A, Varughese, K.I, Arockiasamy, A.
登録日2022-04-26
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献High resolution structure of lectin like Ox-LDL receptor 1 in space group P 32 2 1
To Be Published
5MGT
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Complex of human NKR-P1 and LLT1 in deglycosylated forms
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D, CHLORIDE ION, ...
著者Blaha, J, Skalova, T, Stransky, J, Koval, T, Hasek, J, Yuguang, Z, Harlos, K, Vanek, O, Dohnalek, J.
登録日2016-11-22
公開日2018-06-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse.
Nat Commun, 13, 2022
5MGS
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Human receptor NKR-P1 in deglycosylated form, extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor subfamily B member 1
著者Skalova, T, Blaha, J, Stransky, J, Koval, T, Hasek, J, Yuguang, Z, Harlos, K, Vanek, O, Dohnalek, J.
登録日2016-11-22
公開日2018-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse.
Nat Commun, 13, 2022
6GHV
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BU of 6ghv by Molmil
Structure of a DC-SIGN CRD in complex with high affinity glycomimetic.
分子名称: CALCIUM ION, CD209 antigen, CHLORIDE ION, ...
著者Thepaut, M, Achilli, S, Medve, L, Bernardi, A, Fieschi, F.
登録日2018-05-09
公開日2019-09-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis.
Chemistry, 25, 2019
6YAU
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BU of 6yau by Molmil
CRYSTAL STRUCTURE OF ASGPR 1 IN COMPLEX WITH GN-A.
分子名称: 5-[(2~{R},3~{R},4~{R},5~{R},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-~{N}-[3-(propanoylamino)propyl]pentanamide, Asialoglycoprotein receptor 1, CALCIUM ION
著者Schreuder, H.A, Liesum, A.
登録日2020-03-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.397 Å)
主引用文献Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis.
Adv Sci, 7, 2020
5B1W
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BU of 5b1w by Molmil
Crystal structure of human dendritic cell inhibitory receptor (DCIR) C-type lectin domain in ligand-free form
分子名称: C-type lectin domain family 4 member A, CALCIUM ION
著者Nagae, M, Yamaguchi, Y.
登録日2015-12-21
公開日2016-05-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan
Febs Lett., 590, 2016
7W5D
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High resolution structure of lectin-ike Ox-LDL Receptor 1
分子名称: Oxidized low-density lipoprotein receptor 1
著者Tomar, A, Arockiasamy, A.
登録日2021-11-30
公開日2022-12-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.141 Å)
主引用文献High Resolution Structure of Lectin-Like Ox-LDL Receptor 1
To Be Published
6E7D
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BU of 6e7d by Molmil
Structure of the inhibitory NKR-P1B receptor bound to the host-encoded ligand, Clr-b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D, Killer cell lectin-like receptor subfamily B member 1B allele B, ...
著者Balaji, G.R, Rossjohn, J, Berry, R.
登録日2018-07-26
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition.
Nat Commun, 9, 2018
2VUZ
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Crystal structure of Codakine in complex with biantennary nonasaccharide at 1.7A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CODAKINE, ...
著者Gourdine, J.P, Cioci, G.C, Miguet, L, Unverzagt, C, Varrot, A, Gauthier, C, Smith-Ravin, E.J, Imberty, A.
登録日2008-06-02
公開日2008-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High Affinity Interaction between a Bivalve C-Type Lectin and a Biantennary Complex-Type N-Glycan Revealed by Crystallography and Microcalorimetry.
J.Biol.Chem., 283, 2008
2VRP
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BU of 2vrp by Molmil
Structure of rhodocytin
分子名称: AGGRETIN ALPHA CHAIN, AGGRETIN BETA CHAIN, CHLORIDE ION, ...
著者Watson, A.A, O'Callaghan, C.A.
登録日2008-04-09
公開日2008-07-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal Structure of Rhodocytin, a Ligand for the Platelet-Activating Receptor Clec-2.
Protein Sci., 17, 2008
5B1X
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BU of 5b1x by Molmil
Crystal structure of human dendritic cell inhibitory receptor (DCIR) C-type lectin domain in complex with biantennary glycan
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, C-type lectin domain family 4 member A, CALCIUM ION
著者Nagae, M, Yamaguchi, Y.
登録日2015-12-21
公開日2016-05-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.902 Å)
主引用文献Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan
Febs Lett., 590, 2016
2XR5
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BU of 2xr5 by Molmil
Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo dimannoside mimic.
分子名称: CALCIUM ION, CD209 ANTIGEN, CHLORIDE ION, ...
著者Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F.
登録日2010-09-10
公開日2011-10-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-Type Lectin Dc-Sign. Structural Requirements for Selectivity and Ligand Design.
J.Am.Chem.Soc., 135, 2013
7YTQ
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BU of 7ytq by Molmil
Human langerin carbohydrate recognition domain in complex with an alpha-mannoside ligand
分子名称: CALCIUM ION, CD207 molecule, CHLORIDE ION, ...
著者Wangkanont, K.
登録日2022-08-16
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Human langerin carbohydrate recognition domain in complex with an alpha-mannoside ligand
To Be Published
8TS0
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BU of 8ts0 by Molmil
Crystal Structure of human ASGR1 CRD (Carbohydrate Recognition Domain) bound to 8M24 Fab
分子名称: 8M24 Fab Heavy chain, 8M24 Fab Light chain, Asialoglycoprotein receptor 1, ...
著者Sampathkumar, P, Li, Y.
登録日2023-08-10
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Targeted protein degradation systems to enhance Wnt signaling.
Elife, 13, 2024
8W9J
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BU of 8w9j by Molmil
Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab
分子名称: Anti-human CLEC12A antibody 50C1 heavy chain, Anti-human CLEC12A antibody 50C1 light chain, C-type lectin domain family 12 member A
著者Mori, S, Nagae, M, Yamasaki, S.
登録日2023-09-05
公開日2024-03-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
8URF
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BU of 8urf by Molmil
Crystal Structure of human ASGR2 CRD (Carbohydrate Recognition Domain) bound to 8G8 Fab
分子名称: 8G8 Fab Heavy Chain, 8G8 Fab Light Chain, Asialoglycoprotein receptor 2, ...
著者Sampathumar, P, Li, Y.
登録日2023-10-25
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Targeted protein degradation systems to enhance Wnt signaling.
Elife, 13, 2024
8W8T
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BU of 8w8t by Molmil
Crystal structure of human CLEC12A CRD
分子名称: C-type lectin domain family 12 member A, SULFATE ION
著者Mori, S, Nagae, M, Yamasaki, S.
登録日2023-09-04
公開日2024-03-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
5F2Q
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C-type lectin from Bothrops jararacussu
分子名称: C-type lectin BJcuL, CALCIUM ION, SODIUM ION
著者de Padua, R.A.P, Pinheiro, M.P, Sartim, M.A, Sampaio, S.V, Nonato, M.C.
登録日2015-12-02
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献C-type lectin from Bothrops jararacussu
To Be Published
5J2S
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NKR-P1B from Rattus norvegicus
分子名称: Killer cell lectin-like receptor subfamily B member 1B allele A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Skalova, T, Vanek, O, Blaha, J, Duskova, J, Hasek, J, Koval, T, Dohnalek, J.
登録日2016-03-30
公開日2017-10-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of NKR-P1B from Rattus norvegicus
To Be Published
5JPV
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Efficient targeting of the asialoglycoprotein receptor by polyvalent display of a compact galactoseamine mimic
分子名称: Asialoglycoprotein receptor 1, CALCIUM ION, CHLORIDE ION, ...
著者Liu, S.
登録日2016-05-04
公開日2017-06-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor.
J. Am. Chem. Soc., 139, 2017
5G6U
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Crystal structure of langerin carbohydrate recognition domain with GlcNS6S
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Porkolab, V, Chabrol, E, Varga, N, Ordanini, S, Sutkeviciute, I, Thepaut, M, Bernardi, A, Fieschi, F.
登録日2016-07-21
公開日2018-02-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.844 Å)
主引用文献Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
ACS Chem. Biol., 13, 2018
8EA8
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NKG2D complexed with inhibitor 4a
分子名称: DI(HYDROXYETHYL)ETHER, N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamide, NKG2-D type II integral membrane protein, ...
著者Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S.
登録日2022-08-28
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EA7
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NKG2D complexed with inhibitor 3g
分子名称: (4M)-N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-(1-methyl-1H-pyrazol-5-yl)-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide, DI(HYDROXYETHYL)ETHER, NKG2-D type II integral membrane protein
著者Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S.
登録日2022-08-28
公開日2023-05-03
最終更新日2023-05-10
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023

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