6PWR
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2XR6
| Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo trimannoside mimic. | 分子名称: | 2-AZIDOETHANOL, CALCIUM ION, CD209 ANTIGEN, ... | 著者 | Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F. | 登録日 | 2010-09-10 | 公開日 | 2011-10-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Unique Dc-Sign Clustering Activity of a Small Glycomimetic: A Lesson for Ligand Design. Acs Chem.Biol., 9, 2014
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7XMP
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5MGT
| Complex of human NKR-P1 and LLT1 in deglycosylated forms | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D, CHLORIDE ION, ... | 著者 | Blaha, J, Skalova, T, Stransky, J, Koval, T, Hasek, J, Yuguang, Z, Harlos, K, Vanek, O, Dohnalek, J. | 登録日 | 2016-11-22 | 公開日 | 2018-06-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse. Nat Commun, 13, 2022
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5MGS
| Human receptor NKR-P1 in deglycosylated form, extracellular domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor subfamily B member 1 | 著者 | Skalova, T, Blaha, J, Stransky, J, Koval, T, Hasek, J, Yuguang, Z, Harlos, K, Vanek, O, Dohnalek, J. | 登録日 | 2016-11-22 | 公開日 | 2018-05-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse. Nat Commun, 13, 2022
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6GHV
| Structure of a DC-SIGN CRD in complex with high affinity glycomimetic. | 分子名称: | CALCIUM ION, CD209 antigen, CHLORIDE ION, ... | 著者 | Thepaut, M, Achilli, S, Medve, L, Bernardi, A, Fieschi, F. | 登録日 | 2018-05-09 | 公開日 | 2019-09-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis. Chemistry, 25, 2019
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6YAU
| CRYSTAL STRUCTURE OF ASGPR 1 IN COMPLEX WITH GN-A. | 分子名称: | 5-[(2~{R},3~{R},4~{R},5~{R},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-~{N}-[3-(propanoylamino)propyl]pentanamide, Asialoglycoprotein receptor 1, CALCIUM ION | 著者 | Schreuder, H.A, Liesum, A. | 登録日 | 2020-03-13 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.397 Å) | 主引用文献 | Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis. Adv Sci, 7, 2020
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5B1W
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7W5D
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6E7D
| Structure of the inhibitory NKR-P1B receptor bound to the host-encoded ligand, Clr-b | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D, Killer cell lectin-like receptor subfamily B member 1B allele B, ... | 著者 | Balaji, G.R, Rossjohn, J, Berry, R. | 登録日 | 2018-07-26 | 公開日 | 2018-10-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition. Nat Commun, 9, 2018
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2VUZ
| Crystal structure of Codakine in complex with biantennary nonasaccharide at 1.7A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CODAKINE, ... | 著者 | Gourdine, J.P, Cioci, G.C, Miguet, L, Unverzagt, C, Varrot, A, Gauthier, C, Smith-Ravin, E.J, Imberty, A. | 登録日 | 2008-06-02 | 公開日 | 2008-08-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | High Affinity Interaction between a Bivalve C-Type Lectin and a Biantennary Complex-Type N-Glycan Revealed by Crystallography and Microcalorimetry. J.Biol.Chem., 283, 2008
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2VRP
| Structure of rhodocytin | 分子名称: | AGGRETIN ALPHA CHAIN, AGGRETIN BETA CHAIN, CHLORIDE ION, ... | 著者 | Watson, A.A, O'Callaghan, C.A. | 登録日 | 2008-04-09 | 公開日 | 2008-07-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Crystal Structure of Rhodocytin, a Ligand for the Platelet-Activating Receptor Clec-2. Protein Sci., 17, 2008
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5B1X
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2XR5
| Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo dimannoside mimic. | 分子名称: | CALCIUM ION, CD209 ANTIGEN, CHLORIDE ION, ... | 著者 | Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F. | 登録日 | 2010-09-10 | 公開日 | 2011-10-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-Type Lectin Dc-Sign. Structural Requirements for Selectivity and Ligand Design. J.Am.Chem.Soc., 135, 2013
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7YTQ
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8TS0
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8W9J
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8URF
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8W8T
| Crystal structure of human CLEC12A CRD | 分子名称: | C-type lectin domain family 12 member A, SULFATE ION | 著者 | Mori, S, Nagae, M, Yamasaki, S. | 登録日 | 2023-09-04 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. Int.Immunol., 36, 2024
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5F2Q
| C-type lectin from Bothrops jararacussu | 分子名称: | C-type lectin BJcuL, CALCIUM ION, SODIUM ION | 著者 | de Padua, R.A.P, Pinheiro, M.P, Sartim, M.A, Sampaio, S.V, Nonato, M.C. | 登録日 | 2015-12-02 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | C-type lectin from Bothrops jararacussu To Be Published
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5J2S
| NKR-P1B from Rattus norvegicus | 分子名称: | Killer cell lectin-like receptor subfamily B member 1B allele A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Skalova, T, Vanek, O, Blaha, J, Duskova, J, Hasek, J, Koval, T, Dohnalek, J. | 登録日 | 2016-03-30 | 公開日 | 2017-10-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of NKR-P1B from Rattus norvegicus To Be Published
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5JPV
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5G6U
| Crystal structure of langerin carbohydrate recognition domain with GlcNS6S | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Porkolab, V, Chabrol, E, Varga, N, Ordanini, S, Sutkeviciute, I, Thepaut, M, Bernardi, A, Fieschi, F. | 登録日 | 2016-07-21 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.844 Å) | 主引用文献 | Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition. ACS Chem. Biol., 13, 2018
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8EA8
| NKG2D complexed with inhibitor 4a | 分子名称: | DI(HYDROXYETHYL)ETHER, N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamide, NKG2-D type II integral membrane protein, ... | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | 登録日 | 2022-08-28 | 公開日 | 2023-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EA7
| NKG2D complexed with inhibitor 3g | 分子名称: | (4M)-N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-(1-methyl-1H-pyrazol-5-yl)-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide, DI(HYDROXYETHYL)ETHER, NKG2-D type II integral membrane protein | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | 登録日 | 2022-08-28 | 公開日 | 2023-05-03 | 最終更新日 | 2023-05-10 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D. Proc.Natl.Acad.Sci.USA, 120, 2023
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