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6WZL
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BU of 6wzl by Molmil
LY3041658 Fab bound to CXCL7
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, C-X-C motif chemokine 7, LY3041658 Fab heavy chain, ...
著者Durbin, J.D, Druzina, Z.
登録日2020-05-14
公開日2020-11-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
6WZM
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BU of 6wzm by Molmil
LY3041658 Fab bound to CXCL8
分子名称: 1,2-ETHANEDIOL, Interleukin-8, LY3041658 Fab heavy chain, ...
著者Durbin, J.D, Druzina, Z.
登録日2020-05-14
公開日2020-11-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
6WZJ
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BU of 6wzj by Molmil
LY3041658 Fab bound to CXCL2
分子名称: C-X-C motif chemokine 2, LY3041658 Fab Heavy Chain, LY3041658 Fab Light Chain
著者Durbin, J.D, Druzina, Z.
登録日2020-05-14
公開日2020-11-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
3HP3
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BU of 3hp3 by Molmil
Crystal structure of CXCL12
分子名称: CXCL12 protein, GOLD ION
著者Murphy, J.W, Lolis, E, Xiong, Y, Yuan, H, Crichlow, G.
登録日2009-06-03
公開日2010-01-26
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family
Proteins, 78, 2009
2EOT
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BU of 2eot by Molmil
SOLUTION STRUCTURE OF EOTAXIN, AN ENSEMBLE OF 32 NMR SOLUTION STRUCTURES
分子名称: EOTAXIN
著者Crump, M.P, Rajarathnam, K, Kim, K.-S, Clark-Lewis, I, Sykes, B.D.
登録日1998-06-29
公開日1998-11-11
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J.Biol.Chem., 273, 1998
2FJ2
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BU of 2fj2 by Molmil
Crystal Structure of Viral Macrophage Inflammatory Protein-II
分子名称: Viral macrophage inflammatory protein-II
著者Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z.
登録日2005-12-30
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of chemically synthesized vMIP-II.
Proteins, 67, 2007
3KBX
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BU of 3kbx by Molmil
Human macrophage inflammatory protein-1 alpha L3M_V63M
分子名称: ACETATE ION, CCL3, POTASSIUM ION
著者Guo, Q, Ren, M, Tang, W.-J.
登録日2009-10-20
公開日2010-10-27
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Structural basis for the oligomerization of macrophage inflammatory protein-1 alpha
To be Published
2FHT
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BU of 2fht by Molmil
Crystal Structure of Viral Macrophage Inflammatory Protein-II
分子名称: Viral macrophage inflammatory protein-II
著者Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z.
登録日2005-12-27
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of chemically synthesized vMIP-II.
Proteins, 67, 2007
4OIK
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BU of 4oik by Molmil
(Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ...
著者Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H.
登録日2014-01-19
公開日2014-05-07
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献(Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4OIJ
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X-ray crystal structure of racemic non-glycosylated chemokine Ser-CCL1
分子名称: C-C motif chemokine 1, D-Ser-CCL1, SULFATE ION
著者Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H.
登録日2014-01-19
公開日2014-05-07
最終更新日2014-05-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献(Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
7STA
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BU of 7sta by Molmil
X-ray Crystal Structure of Truncated Human Chemokine CCL19 (7-70)
分子名称: C-C motif chemokine 19
著者Lewandowski, E.M, Kroeck, K, Chen, Y.
登録日2021-11-12
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights into Molecular Recognition by Human Chemokine CCL19.
Biochemistry, 61, 2022
4R9W
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BU of 4r9w by Molmil
Crystal structure of platelet factor 4 complexed with fondaparinux
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Platelet factor 4
著者Cai, Z, Zhu, Z, Liu, Q, Greene, M.I.
登録日2014-09-08
公開日2015-12-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
Nat Commun, 6, 2015
4R8I
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BU of 4r8i by Molmil
High Resolution Structure of a Mirror-Image RNA Oligonucleotide Aptamer in Complex with the Chemokine CCL2
分子名称: C-C motif chemokine 2, Mirror-Image RNA Oligonucleotide Aptamer NOXE36, POTASSIUM ION, ...
著者Oberthuer, D, Achenbach, J, Gabdulkhakov, A, Falke, S, Buchner, K, Maasch, C, Rehders, D, Klussmann, S, Betzel, C.
登録日2014-09-02
公開日2015-04-29
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.
Nat Commun, 6, 2015
4R9Y
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BU of 4r9y by Molmil
Crystal structure of KKOFab in complex with platelet factor 4
分子名称: Platelet factor 4, Platelet factor 4 antibody KKO heavy chain, Platelet factor 4 antibody KKO light chain
著者Cai, Z, Zhu, Z, Liu, Q, Greene, M.I.
登録日2014-09-08
公開日2015-12-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (4.11 Å)
主引用文献Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
Nat Commun, 6, 2015
4RAU
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BU of 4rau by Molmil
crystal structure of RTOFab in complex with human PF4
分子名称: Platelet factor 4, RTOFab heavy chain, RTOFab light chain
著者Cai, Z, Zhu, Z, Liu, Q, Greene, M.I.
登録日2014-09-11
公開日2016-03-16
実験手法X-RAY DIFFRACTION (3.74 Å)
主引用文献crystal structure of RTOFab in complex with platelet factor 4
To be Published
4RA8
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BU of 4ra8 by Molmil
Structure analysis of the Mip1a P8A mutant
分子名称: C-C motif chemokine 3
著者Liang, W.G, Ren, M, Guo, Q, Tang, W.J.
登録日2014-09-09
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
5COY
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BU of 5coy by Molmil
Crystal structure of CC chemokine 5 (CCL5)
分子名称: C-C motif chemokine 5, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
著者Liang, W.G, Tang, W.
登録日2015-07-20
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.443 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5COR
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BU of 5cor by Molmil
X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) N-TERMINAL-SWITCH POLYMER
分子名称: ACETATE ION, C-C motif chemokine 3, HEXANE-1,6-DIOL
著者Liang, W.G, Tang, W.
登録日2015-07-20
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5D14
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BU of 5d14 by Molmil
The atomic resolution crystal structure of human IL-8
分子名称: Interleukin-8
著者Brzezinski, K, Pompeu, Y, Lu, S, Jakoncic, J, Ostrov, D.A.
登録日2015-08-03
公開日2015-12-23
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献The atomic resolution crystal structure of human IL-8
To Be Published
5D65
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BU of 5d65 by Molmil
X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-C motif chemokine 3, CHLORIDE ION, ...
著者Liang, W.G, Hwang, D.Y, Zulueta, M.M, Hung, S.C, Tang, W.
登録日2015-08-11
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EKI
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BU of 5eki by Molmil
Crystal Structure of Truncated CCL21
分子名称: C-C motif chemokine 21, SULFATE ION
著者Lewandowski, E.M, Smith, E.W, Chen, Y.
登録日2015-11-03
公開日2016-10-05
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic Structure of Truncated CCL21 and the Putative Sulfotyrosine-Binding Site.
Biochemistry, 55, 2016
5DNF
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BU of 5dnf by Molmil
Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, C-C motif chemokine 5, ...
著者Liang, W.G, Tang, W.
登録日2015-09-10
公開日2016-04-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.549 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CMD
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BU of 5cmd by Molmil
Oligomer crystal structure of CC chemokine 5 (CCL5)
分子名称: C-C motif chemokine 5, SULFATE ION
著者Liang, W.G, Tang, W.-J.
登録日2015-07-16
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.086 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
7S5A
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BU of 7s5a by Molmil
Crystal structure of human chemokine CCL8
分子名称: C-C motif chemokine 8
著者Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-10
公開日2021-09-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
1F9P
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CRYSTAL STRUCTURE OF CONNECTIVE TISSUE ACTIVATING PEPTIDE-III(CTAP-III) COMPLEXED WITH POLYVINYLSULFONIC ACID
分子名称: CONNECTIVE TISSUE ACTIVATING PEPTIDE-III, ETHANESULFONIC ACID
著者Yang, J, Faulk, T, Aster, R, Visentin, G, Edwards, B, Castor, C.
登録日2000-07-11
公開日2003-08-26
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of the CXC Chemokine, Connective Tissue Activating Peptide-III, Complexed with the Heparin Analogue, Polyvinylsulfonic Acid
To be Published

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