2VXW

Structural and Functional Studies of the Potent Anti-HIV Chemokine Variant P2-RANTES

Summary for 2VXW

Related1U4P 1U4R 1HRJ 1U4M 1RTO 1EQT 1U4L 1B3A 1RTN
DescriptorC-C MOTIF CHEMOKINE 5 (2 entities in total)
Functional Keywordsimmune system, glycoprotein, cell-cell fusion, inflammatory response, hiv entry, chemotaxis
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted P13501
Total number of polymer chains4
Total molecular weight31672.48
Authors
Jin, H.,Li, P.,LiWang, P.J. (deposition date: 2008-07-12, release date: 2008-07-29, Last modification date: 2012-08-22)
Primary citation
Jin, H.,Kagiampakis, I.,Li, P.,Liwang, P.J.
Structural and Functional Studies of the Potent Anti-HIV Chemokine Variant P2-Rantes.
Proteins, 78:295-, 2010
PubMed: 19722264 (PDB entries with the same primary citation)
DOI: 10.1002/PROT.22542
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.241140.4%1.7%7.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2vxw
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Molmil generated image of 2vxw
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Molmil generated image of 2vxw
rotated about y axis by 90°