PDB: 187 件ウェブページステータス検索Chemie searchBIRD

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8EML	Crystal Structure of Gsx2 Homeodomain in Complex with DNA 分子名称: DNA (5'-D(P*GP*AP*GP*CP*TP*AP*AP*TP*TP*AP*AP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*TP*TP*AP*AP*TP*TP*AP*GP*CP*TP*C)-3'), GS homeobox 2, ... 著者 Webb, J.A, Kovall, R.A. 登録日 2022-09-28 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal Structure of Gsx2 Homeodomain in Complex with DNA To Be Published
1ZTR	Solution structure of Engrailed homeodomain L16A mutant 分子名称: Segmentation polarity homeobox protein engrailed 著者 Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R. 登録日 2005-05-27 公開日 2005-10-18 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of a protein denatured state and folding intermediate. Nature, 437, 2005
3CMY	Structure of a homeodomain in complex with DNA 分子名称: 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ... 著者 Birrane, G, Ladias, J.A.A, Soni, A. 登録日 2008-03-24 公開日 2009-02-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for DNA Recognition by the Human PAX3 Homeodomain. Biochemistry, 48, 2009
8IK5	Transcription factor LMX1a homeobox domain in complex with Wnt1 promoter 分子名称: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), GLYCEROL, ... 著者 Lv, M.Q, Lin, L.Q. 登録日 2023-02-28 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.989 Å) 主引用文献 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
8IKE	Transcription factors LMX1a mutant-R199A homeobox domain complex with Wnt1 promoter 分子名称: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), LMX1A factor 著者 Lv, M.Q, Lin, L.Q. 登録日 2023-02-28 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
8ILW	Transcription factor LMX1a homeobox domain in complex with Pitx3 promoter 分子名称: DNA (5'-D(*CP*AP*AP*CP*AP*CP*TP*TP*AP*AP*TP*CP*CP*AP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*GP*AP*TP*TP*AP*AP*GP*TP*GP*TP*T)-3'), LMX1A factor 著者 Lv, M.Q, Lin, L.Q. 登録日 2023-03-04 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.712 Å) 主引用文献 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
8P7G	Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS 分子名称: Paired mesoderm homeobox protein 2B 著者 Russo, L, Diana, D, Fattorusso, R. 登録日 2023-05-30 公開日 2024-05-15 最終更新日 2024-06-26 実験手法 SOLUTION NMR 主引用文献 Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS. Chem Sci, 15, 2024
1JGG	Even-skipped Homeodomain Complexed to AT-rich DNA 分子名称: 5'-D(P*AP*AP*TP*TP*CP*AP*AP*TP*TP*A)-3', 5'-D(P*TP*AP*AP*TP*TP*GP*AP*AP*TP*T)-3', Segmentation Protein Even-Skipped 著者 Hirsch, J.A, Aggarwal, A.K. 登録日 2001-06-25 公開日 2001-07-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity. EMBO J., 14, 1995
5EF6	Structure of HOXB13 complex with methylated DNA 分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2015-10-23 公開日 2017-02-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
5EEA	Structure of HOXB13-DNA(CAA) complex 分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2015-10-22 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.195 Å) 主引用文献 Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife, 7, 2018
5EDN	Structure of HOXB13-DNA(TCG) complex 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(P*GP*GP*AP*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*GP*TP*CP*C)-3'), ... 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2015-10-21 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife, 7, 2018
1K61	MATALPHA2 HOMEODOMAIN BOUND TO DNA 分子名称: 5'-D(*(5IU)P*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*AP*CP*AP*TP*G)-3', 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*CP*AP*CP*GP*C)-3', Mating-type protein alpha-2 著者 Aishima, J, Gitti, R.K, Noah, J.E, Gan, H.H, Schlick, T, Wolberger, C. 登録日 2001-10-14 公開日 2002-12-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Hoogsteen base pair embedded in undistorted B-DNA NUCLEIC ACIDS RES., 30, 2002
1LE8	Crystal Structure of the MATa1/MATalpha2-3A Heterodimer Bound to DNA Complex 分子名称: 5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*CP*AP*TP*CP*A)-3', 5'-D(*TP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*AP*CP*AP*TP*G)-3', MATING-TYPE PROTEIN A-1, ... 著者 Ke, A, Mathias, J.R, Vershon, A.K, Wolberger, C. 登録日 2002-04-09 公開日 2002-05-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Thermodynamic Characterization of the DNA Binding Properties of a Triple Alanine Mutant of MATalpha2 Structure, 10, 2002
1IG7	Msx-1 Homeodomain/DNA Complex Structure 分子名称: 5'-D(*CP*AP*CP*TP*AP*AP*TP*TP*GP*AP*AP*GP*G)-3', 5'-D(P*TP*CP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*TP*GP*AP*C)-3', Homeotic protein Msx-1 著者 Hovde, S, Abate-Shen, C, Geiger, J.H. 登録日 2001-04-17 公開日 2001-04-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the Msx-1 homeodomain/DNA complex Biochemistry, 40, 2001
5HOD	Structure of LHX4 transcription factor complexed with DNA 分子名称: DNA (5'-D(P*AP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*GP*TP*AP*AP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*TP*TP*AP*CP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*T)-3'), LIM/homeobox protein Lhx4 著者 Morgunova, E, Yin, Y, Popov, A, Taipale, J. 登録日 2016-01-19 公開日 2017-02-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.682 Å) 主引用文献 Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
2ME6	NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens in complex with the DNA sequence CGACTAATTAGTCG 分子名称: DNA (5'-D(*CP*GP*AP*CP*TP*AP*AP*TP*TP*AP*GP*TP*CP*G)-3'), Homeobox protein GBX-1 著者 Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2013-09-23 公開日 2013-10-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens in complex with the DNA sequence CGACTAATTAGTCG To be Published
2MGQ	Structure of CEH37 Homeodomain 分子名称: Homeobox protein ceh-37 著者 Moon, S, Lee, W. 登録日 2013-11-04 公開日 2014-11-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of CEH37 Homeodomain To be Published
2M0C	Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C 分子名称: Homeobox protein aristaless-like 4 著者 Xu, X, Eletsky, A, Pulavarti, S, Lee, D, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) 登録日 2012-10-24 公開日 2012-11-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C To be Published
1NK3	VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), HOMEOBOX PROTEIN VND 著者 Gruschus, J.M, Tsao, D.H.H, Wang, L.-H, Nirenberg, M, Ferretti, J.A. 登録日 1998-05-06 公開日 1998-12-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry, 36, 1997
1NK2	VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, 20 STRUCTURES 分子名称: DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), HOMEOBOX PROTEIN VND 著者 Gruschus, J.M, Tsao, D.H.H, Wang, L.-H, Nirenberg, M, Ferretti, J.A. 登録日 1998-05-06 公開日 1999-02-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry, 36, 1997
1ENH	STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN 分子名称: ENGRAILED HOMEODOMAIN 著者 Clarke, N.D, Kissinger, C.R, Desjarlais, J, Gilliland, G.L, Pabo, C.O. 登録日 1994-05-20 公開日 1994-08-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies of the engrailed homeodomain. Protein Sci., 3, 1994
1F43	SOLUTION STRUCTURE OF THE MATA1 HOMEODOMAIN 分子名称: MATING-TYPE PROTEIN A-1 著者 Anderson, J.S, Forman, M, Modleski, S, Dahlquist, F.W, Baxter, S.M. 登録日 2000-06-07 公開日 2000-07-26 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Cooperative ordering in homeodomain-DNA recognition: solution structure and dynamics of the MATa1 homeodomain. Biochemistry, 39, 2000
2M34	NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens 分子名称: Homeobox protein GBX-1 著者 Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Partnership for Stem Cell Biology (STEMCELL), Joint Center for Structural Genomics (JCSG) 登録日 2013-01-09 公開日 2013-01-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens To be Published
2ME0	NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens solved in the presence of the DNA sequence CGACTAATTAGTCG 分子名称: Homeobox protein GBX-1 著者 Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2013-09-20 公開日 2013-10-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens solved in the presence of the DNA sequence CGACTAATTAGTCG To be Published
1P7J	Crystal structure of engrailed homeodomain mutant K52E 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed 著者 Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. 登録日 2003-05-02 公開日 2003-10-14 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003

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