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3C7N
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BU of 3c7n by Molmil
Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ...
著者Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R.
登録日2008-02-07
公開日2008-05-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.115 Å)
主引用文献Structure of the Hsp110:Hsc70 nucleotide exchange machine
Mol.Cell, 31, 2008
1HJO
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BU of 1hjo by Molmil
ATPase domain of human heat shock 70kDa protein 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ...
著者Osipiuk, J, Walsh, M.A, Freeman, B.C, Morimoto, R.I, Joachimiak, A.
登録日1998-10-13
公開日1998-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a new crystal form of human Hsp70 ATPase domain.
Acta Crystallogr.,Sect.D, 55, 1999
3D2E
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BU of 3d2e by Molmil
Crystal structure of a complex of Sse1p and Hsp70, Selenomethionine-labeled crystals
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Heat shock 70 kDa protein 1, ...
著者Polier, S, Bracher, A.
登録日2008-05-08
公開日2008-06-17
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding.
Cell(Cambridge,Mass.), 133, 2008
1DKZ
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BU of 1dkz by Molmil
THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 NATIVE CRYSTALS
分子名称: SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES)
著者Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A.
登録日1996-06-03
公開日1996-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
3D2F
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BU of 3d2f by Molmil
Crystal structure of a complex of Sse1p and Hsp70
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Heat shock 70 kDa protein 1, ...
著者Polier, S, Bracher, A.
登録日2008-05-08
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding.
Cell(Cambridge,Mass.), 133, 2008
3CQX
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BU of 3cqx by Molmil
Chaperone Complex
分子名称: BAG family molecular chaperone regulator 2, Heat shock cognate 71 kDa protein, SODIUM ION, ...
著者Xu, Z, Nix, J.C, Misra, S.
登録日2008-04-03
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2
Nat.Struct.Mol.Biol., 15, 2008
1DKX
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THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 SELENOMETHIONYL CRYSTALS
分子名称: SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES)
著者Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A.
登録日1996-06-03
公開日1996-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
1DKY
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BU of 1dky by Molmil
THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 2 NATIVE CRYSTALS
分子名称: DNAK, PEPTIDE SUBSTRATE
著者Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A.
登録日1996-06-03
公開日1996-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
3DPP
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BU of 3dpp by Molmil
Crystal structure of the substrate binding domain of E. coli DnaK in complex with a long pyrrhocoricin-derived inhibitor peptide (form A)
分子名称: Chaperone protein dnaK, SULFATE ION, inhibitor peptide
著者Roujeinikova, A.
登録日2008-07-09
公開日2009-03-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies.
J.Bacteriol., 191, 2009
3DPQ
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BU of 3dpq by Molmil
Crystal structure of the substrate binding domain of E. coli DnaK in complex with a long pyrrhocoricin-derived inhibitor peptide (form B)
分子名称: Chaperone protein dnaK, SULFATE ION, inhibitor peptide
著者Roujeinikova, A.
登録日2008-07-09
公開日2009-03-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies.
J.Bacteriol., 191, 2009
3DPO
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BU of 3dpo by Molmil
Crystal structure of the substrate binding domain of E. coli DnaK in complex with a short pyrrhocoricin-derived inhibitor peptide
分子名称: Chaperone protein dnaK, SULFATE ION, inhibitor peptide
著者Roujeinikova, A.
登録日2008-07-09
公開日2009-03-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies
J.Bacteriol., 191, 2009
1HPM
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BU of 1hpm by Molmil
HOW POTASSIUM AFFECTS THE ACTIVITY OF THE MOLECULAR CHAPERONE HSC70. II. POTASSIUM BINDS SPECIFICALLY IN THE ATPASE ACTIVE SITE
分子名称: 44K ATPASE FRAGMENT (N-TERMINAL) OF 7O kD HEAT-SHOCK COGNATE PROTEIN, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Wilbanks, S.M, Mckay, D.B.
登録日1995-03-24
公開日1995-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献How potassium affects the activity of the molecular chaperone Hsc70. II. Potassium binds specifically in the ATPase active site.
J.Biol.Chem., 270, 1995
1KAY
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BU of 1kay by Molmil
70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71A MUTANT
分子名称: 70KD HEAT SHOCK COGNATE PROTEIN, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者O'Brien, M.C, Flaherty, K.M, Mckay, D.B.
登録日1996-04-15
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Lysine 71 of the chaperone protein Hsc70 Is essential for ATP hydrolysis.
J.Biol.Chem., 271, 1996
1BUP
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BU of 1bup by Molmil
T13S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Sousa, M.C, Mckay, D.B.
登録日1998-09-03
公開日1998-09-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
Biochemistry, 37, 1998
1BPR
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BU of 1bpr by Molmil
NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, MINIMIZED AVERAGE STRUCTURE
分子名称: DNAK
著者Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P.
登録日1998-08-11
公開日1999-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction.
Biochemistry, 37, 1998
1KAX
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BU of 1kax by Molmil
70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71M MUTANT
分子名称: 70KD HEAT SHOCK COGNATE PROTEIN, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者O'Brien, M.C, Flaherty, K.M, Mckay, D.B.
登録日1996-04-15
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Lysine 71 of the chaperone protein Hsc70 Is essential for ATP hydrolysis.
J.Biol.Chem., 271, 1996
1KAZ
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BU of 1kaz by Molmil
70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71E MUTANT
分子名称: 70KD HEAT SHOCK COGNATE PROTEIN, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者O'Brien, M.C, Flaherty, K.M, Mckay, D.B.
登録日1996-04-15
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Lysine 71 of the chaperone protein Hsc70 Is essential for ATP hydrolysis.
J.Biol.Chem., 271, 1996
6G3R
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BU of 6g3r by Molmil
Structure of tellurium-centred Anderson-Evans polyoxotungstate (TEW) bound to the nucleotide binding domain of HSP70. Structure one of two TEW-HSP70 structures deposited.
分子名称: 6-tungstotellurate(VI), ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A, ...
著者Mac Sweeney, A, Chambovey, A, Wicki, M, Mueller, M, Artico, N, Lange, R, Bijelic, A, Breibeck, J, Rompel, A.
登録日2018-03-26
公開日2018-10-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms.
PLoS ONE, 13, 2018
6G3S
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BU of 6g3s by Molmil
Structure of tellurium-centred Anderson-Evans polyoxotungstate (TEW) bound to the nucleotide binding domain of HSP70. Second structure of two TEW-HSP70 structures deposited.
分子名称: 6-tungstotellurate(VI), ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A, ...
著者Mac Sweeney, A, Chambovey, A, Wicki, M, Mueller, M, Artico, N, Lange, R, Bijelic, A, Breibeck, J, Rompel, A.
登録日2018-03-26
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms.
PLoS ONE, 13, 2018
6H54
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CRYSTAL STRUCTURE OF BOVINE HSC70(AA1-554)E213A/D214A IN COMPLEX WITH INHIBITOR VER155008
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, GLYCEROL, ...
著者Plank, C, Zehe, M, Grimm, C, Sotriffer, C.
登録日2018-07-23
公開日2019-08-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct.
Acs Chem.Biol., 2024
6HAB
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BU of 6hab by Molmil
Crystal structure of BiP V461F (apo)
分子名称: DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP
著者Yan, Y, Ron, D.
登録日2018-08-07
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP.
Nat Commun, 10, 2019
6ZYI
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BU of 6zyi by Molmil
Crystal structure of HSP70 ATPase domain in complex with ADP and calcium
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70kDa protein 1A variant
著者Yan, Y, Preissler, S, Ron, D.
登録日2020-08-01
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020
6ZYJ
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BU of 6zyj by Molmil
Crystal structure of Hsc70 ATPase domain in complex with ADP and calcium
分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Yan, Y, Preissler, S, Ron, D.
登録日2020-08-01
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020
6ZYH
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BU of 6zyh by Molmil
Crystal structure of GRP78 (70kDa heat shock protein 5 / BiP) ATPase domain in complex with ADP and calcium
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Endoplasmic reticulum chaperone BiP
著者Yan, Y, Preissler, S, Ron, D.
登録日2020-08-01
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020
7A4U
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Crystal structure of lid-truncated apo BiP in an oligomeric state
分子名称: Endoplasmic reticulum chaperone BiP, GLYCEROL
著者Perera, L.A, Ron, D.
登録日2020-08-20
公開日2020-12-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes.
Elife, 9, 2020

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