3DPP

Crystal structure of the substrate binding domain of E. coli DnaK in complex with a long pyrrhocoricin-derived inhibitor peptide (form A)

Summary for 3DPP

Entry DOI	10.2210/pdb3dpp/pdb
Related	3DPO 3DPQ
Descriptor	Chaperone protein dnaK, inhibitor peptide, SULFATE ION, ... (4 entities in total)
Functional Keywords	molecular chaperone, dnak, hsp70, substrate-binding domain, pyrrhocoricin inhibitor, atp-binding, chaperone, cytoplasm, dna replication, membrane, nucleotide-binding, phosphoprotein, stress response, peptide binding protein
Biological source	Escherichia coli More
Cellular location	Cytoplasm : P0A6Y8
Total number of polymer chains	4
Total formula weight	52671.46
Authors	Roujeinikova, A. (deposition date: 2008-07-09, release date: 2009-03-10, Last modification date: 2023-08-30)
Primary citation	Liebscher, M.,Roujeinikova, A. Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies. J.Bacteriol., 191:1456-1462, 2009 Cited by PubMed: 19103929 DOI: 10.1128/JB.01131-08 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation