5DZ2
 
 | | Geosmin synthase from Streptomyces coelicolor N-terminal domain complexed with three Mg2+ ions and alendronic acid | | 分子名称: | ALENDRONATE, Germacradienol/geosmin synthase, MAGNESIUM ION | | 著者 | Harris, G.G, Lombardi, P.M, Pemberton, T.A, Matsui, T, Weiss, T.M, Cole, K.E, Koksal, M, Murphy, F.V, Vedula, L.S, Chou, W.K.W, Cane, D.E, Christianson, D.W. | | 登録日 | 2015-09-25 | | 公開日 | 2015-12-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.111 Å) | | 主引用文献 | Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with alpha alpha Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.
Biochemistry, 54, 2015
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3HFD
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2KB5
 | | Solution NMR Structure of Eosinophil Cationic Protein/RNase 3 | | 分子名称: | Eosinophil cationic protein | | 著者 | Rico, M, Bruix, M, Laurents, D.V, Santoro, J, Jimenez, M, Boix, E, Moussaoui, M, Nogues, M. | | 登録日 | 2008-11-20 | | 公開日 | 2009-06-23 | | 最終更新日 | 2024-11-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The (1)H, (13)C, (15)N resonance assignment, solution structure, and residue level stability of eosinophil cationic protein/RNase 3 determined by NMR spectroscopy
Biopolymers, 91, 2009
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9F09
 | | Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Complex with 2-deoxyribose, 7-Bromo-1H-imidazo[4,5-b]pyridine and 2'-deoxycytidine | | 分子名称: | 2'-DEOXYCYTIDINE, 2-deoxy-beta-D-erythro-pentofuranose, 7-bromanyl-3~{H}-imidazo[4,5-b]pyridine, ... | | 著者 | Ascham, A, Salihovic, A, Burley, G, Grogan, G. | | 登録日 | 2024-04-15 | | 公開日 | 2024-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Gram-scale enzymatic synthesis of 2'-deoxyribonucleoside analogues using nucleoside transglycosylase-2.
Chem Sci, 15, 2024
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9F08
 | | Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Covalent complex with 2-deoxyribose. | | 分子名称: | 2-deoxy-beta-D-erythro-pentofuranose, Nucleoside deoxyribosyltransferase | | 著者 | Ascham, A, Salihovic, A, Burley, G, Grogan, G. | | 登録日 | 2024-04-15 | | 公開日 | 2024-12-04 | | 実験手法 | X-RAY DIFFRACTION (2.371 Å) | | 主引用文献 | Gram-scale enzymatic synthesis of 2'-deoxyribonucleoside analogues using nucleoside transglycosylase-2.
Chem Sci, 15, 2024
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2ZUA
 | | Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Ichimura, T, Yamamura, A, Ohtsuka, J, Miyazono, K, Okai, M, Nagata, K, Tanokura, M. | | 登録日 | 2008-10-15 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Molecular mechanism of distinct salt-dependent enzyme activity of two halophilic nucleoside diphosphate kinases
Biophys.J., 96, 2009
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9GN2
 | | Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Complex with ribose and cytosine | | 分子名称: | 6-AMINOPYRIMIDIN-2(1H)-ONE, Nucleoside deoxyribosyltransferase, alpha-D-ribofuranose | | 著者 | Ascham, A, Salihovic, A, Burley, G, Grogan, G. | | 登録日 | 2024-08-30 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-01-29 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Biocatalytic synthesis of ribonucleoside analogues using nucleoside transglycosylase-2.
Chem Sci, 16, 2025
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9GN4
 | | Nucleoside-2'-deoxyribosyltransferase from Lactobacillus leichmannii. Y7F/D72N mutant with cytidine | | 分子名称: | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, Nucleoside deoxyribosyltransferase | | 著者 | Ascham, A, Salihovic, A, Burley, G, Grogan, G. | | 登録日 | 2024-08-30 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-01-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Biocatalytic synthesis of ribonucleoside analogues using nucleoside transglycosylase-2.
Chem Sci, 16, 2025
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8PQQ
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8PQR
 | | Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to DAD_Immucillin-H | | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Nucleoside 2-deoxyribosyltransferase | | 著者 | Tang, P, Harding, C.J, Czekster, C.M. | | 登録日 | 2023-07-11 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.586 Å) | | 主引用文献 | Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
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8PQT
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8PQP
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8RH3
 | | Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to Gemcitabine | | 分子名称: | (2~{R},3~{R})-4,4-bis(fluoranyl)-2-(hydroxymethyl)oxolan-3-ol, Nucleoside 2-deoxyribosyltransferase | | 著者 | Tang, P, Harding, C.J, Czekster, C.M. | | 登録日 | 2023-12-14 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
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5XF3
 | | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration) | | 分子名称: | (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2017-04-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
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5XF5
 | | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration) | | 分子名称: | (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2017-04-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
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5XF6
 | | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having an ethylenediamine linker | | 分子名称: | DNA (145-MER), ETHANE-1,2-DIAMINE, Histone H2A, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2017-04-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
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5XF4
 | | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration) | | 分子名称: | (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2017-04-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
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2OXT
 | | Crystal structure of Meaban virus nucleoside-2'-O-methyltransferase | | 分子名称: | NUCLEOSIDE-2'-O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE | | 著者 | Mastrangelo, E, Milani, M, Bollati, M, Bolognesi, M. | | 登録日 | 2007-02-21 | | 公開日 | 2007-05-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase
Protein Sci., 16, 2007
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2MAS
 | | PURINE NUCLEOSIDE HYDROLASE WITH A TRANSITION STATE INHIBITOR | | 分子名称: | 2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL, CALCIUM ION, INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE | | 著者 | Degano, M, Schramm, V.L, Sacchettini, J.C. | | 登録日 | 1996-10-17 | | 公開日 | 1997-08-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor.
Biochemistry, 37, 1998
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1J90
 | | Crystal Structure of Drosophila Deoxyribonucleoside Kinase | | 分子名称: | 2'-DEOXYCYTIDINE, Deoxyribonucleoside kinase, SULFATE ION | | 著者 | Johansson, K, Ramaswamy, S, Ljungkrantz, C, Knecht, W, Piskur, J, Munch-Petersen, B, Eriksson, S, Eklund, H. | | 登録日 | 2001-05-23 | | 公開日 | 2001-11-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structural basis for substrate specificities of cellular deoxyribonucleoside kinases.
Nat.Struct.Biol., 8, 2001
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1KIC
 | | Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with inosine | | 分子名称: | CALCIUM ION, INOSINE, NICKEL (II) ION, ... | | 著者 | Versees, W, Decanniere, K, Van Holsbeke, E, Devroede, N, Steyaert, J. | | 登録日 | 2001-12-03 | | 公開日 | 2002-05-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.
J.Biol.Chem., 277, 2002
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1KIE
 | | Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with 3-deaza-adenosine | | 分子名称: | 3-DEAZA-ADENOSINE, CALCIUM ION, NICKEL (II) ION, ... | | 著者 | Versees, W, Decanniere, K, Van Holsbeke, E, Devroede, N, Steyaert, J. | | 登録日 | 2001-12-03 | | 公開日 | 2002-05-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.
J.Biol.Chem., 277, 2002
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6RYR
 | | Nucleosome-CHD4 complex structure (single CHD4 copy) | | 分子名称: | Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | | 著者 | Farnung, L, Ochmann, M, Cramer, P. | | 登録日 | 2019-06-11 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
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6RYU
 | | Nucleosome-CHD4 complex structure (two CHD4 copies) | | 分子名称: | Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | | 著者 | Farnung, L, Ochmann, M, Cramer, P. | | 登録日 | 2019-06-12 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
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2VP0
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