8RH3

Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to Gemcitabine

This is a non-PDB format compatible entry.

Summary for 8RH3

• Entry DOI: 10.2210/pdb8rh3/pdb
• Descriptor: Nucleoside 2-deoxyribosyltransferase, (2~{R},3~{R})-4,4-bis(fluoranyl)-2-(hydroxymethyl)oxolan-3-ol (3 entities in total)
• Functional Keywords: ribosylated, holoprotein, transferase, gemcitabine
• Biological source: Chroococcidiopsis thermalis PCC 7203
• Total number of polymer chains: 4
• Total formula weight: 72126.03

Authors

Tang, P.,Harding, C.J.,Czekster, C.M. (deposition date: 2023-12-14, release date: 2024-02-21, Last modification date: 2024-03-20)

• Primary citation: Tang, P.,Harding, C.J.,Dickson, A.L.,da Silva, R.G.,Harrison, D.J.,Czekster, C.M.; Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.; Acs Catalysis, 14:3090-3102, 2024; PubMed: 38449528; DOI: 10.1021/acscatal.3c06260

Experimental method

X-RAY DIFFRACTION (1.96 Å)