8PQQ

Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q Mutant bound to Clofarabine

Summary for 8PQQ

Entry DOI	10.2210/pdb8pqq/pdb
Descriptor	Nucleoside 2-deoxyribosyltransferase, 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	complex, transferase, clofarabine, protein binding
Biological source	Chroococcidiopsis thermalis PCC 7203 More
Total number of polymer chains	4
Total formula weight	72409.56
Authors	Tang, P.,Harding, C.J.,Czekster, M.C. (deposition date: 2023-07-11, release date: 2024-02-21, Last modification date: 2024-03-20)
Primary citation	Tang, P.,Harding, C.J.,Dickson, A.L.,da Silva, R.G.,Harrison, D.J.,Czekster, C.M. Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase. Acs Catalysis, 14:3090-3102, 2024 Cited by PubMed: 38449528 DOI: 10.1021/acscatal.3c06260 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation