8PQQ
Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q Mutant bound to Clofarabine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D (A, B, D) | Nucleoside 2-deoxyribosyltransferase | polymer | 155 | 17819.4 | 3 | UniProt (K9TVX3) Pfam (PF05014) | Chroococcidiopsis thermalis PCC 7203 | |
| 2 | C (C) | Nucleoside 2-deoxyribosyltransferase | polymer | 154 | 17688.2 | 1 | UniProt (K9TVX3) Pfam (PF05014) | Chroococcidiopsis thermalis PCC 7203 | |
| 3 | E, F, I, J (A, B, C, D) | 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE | non-polymer | 303.7 | 4 | Chemie (CFB) | |||
| 4 | G, H (B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A, B, D: 1 - 155 (UniProt: K9TVX3)
C: 1 - 154 (UniProt: K9TVX3)
| PDB | External Database | Details |
|---|---|---|
| Gln 88 | Glu 88 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gln 88 | Glu 88 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71146.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1263.3 | |
| All* | Total formula weight | 72409.6 |
