8PQQ

Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q Mutant bound to Clofarabine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D	Nucleoside 2-deoxyribosyltransferase	polymer	155	17819.4	3	UniProt (K9TVX3) Pfam (PF05014) In PDB	Chroococcidiopsis thermalis PCC 7203
2	C	Nucleoside 2-deoxyribosyltransferase	polymer	154	17688.2	1	UniProt (K9TVX3) Pfam (PF05014) In PDB	Chroococcidiopsis thermalis PCC 7203
3	A, B, C, D	2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE	non-polymer		303.7	4	Chemie (CFB)
4	B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5		water	water		18.0	220	Chemie (HOH)

Sequence modifications

A, B, D: 1 - 155 (UniProt: K9TVX3)

PDB	External Database	Details
Gln 88	Glu 88	engineered mutation

C: 1 - 154 (UniProt: K9TVX3)

PDB	External Database	Details
Gln 88	Glu 88	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	71146.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1263.3
All*	Total formula weight	72409.6

*Water molecules are not included.