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1EE9
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CRYSTAL STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH NAD
分子名称: 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Monzingo, A.F, Breksa, A, Ernst, S, Appling, D.R, Robertus, J.D.
登録日2000-01-31
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci., 9, 2000
1EHF
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CRYSTAL STRUCTURES OF CYTOCHROME P450NOR AND ITS MUTANTS (SER286 VAL, THR) IN THE FERRIC RESTING STATE AT CRYOGENIC TEMPERATURE: A COMPARATIVE ANALYSIS WITH MONOOXYGENASE CYTOCHROME P450S
分子名称: CYTOCHROME P450NOR, PROTOPORPHYRIN IX CONTAINING FE
著者Shimizu, H, Park, S.
登録日2000-02-21
公開日2000-08-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of cytochrome P450nor and its mutants (Ser286-->Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s.
J.Inorg.Biochem., 81, 2000
1ELS
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CATALYTIC METAL ION BINDING IN ENOLASE: THE CRYSTAL STRUCTURE OF ENOLASE-MN2+-PHOSPHONOACETOHYDROXAMATE COMPLEX AT 2.4 ANGSTROMS RESOLUTION
分子名称: ENOLASE, MANGANESE (II) ION, PHOSPHONOACETOHYDROXAMIC ACID
著者Zhang, E, Hatada, M, Brewer, J.M, Lebioda, L.
登録日1994-04-05
公開日1994-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Catalytic metal ion binding in enolase: the crystal structure of an enolase-Mn2+-phosphonoacetohydroxamate complex at 2.4-A resolution.
Biochemistry, 33, 1994
2VJB
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BU of 2vjb by Molmil
Torpedo Californica Acetylcholinesterase In Complex With A Non Hydrolysable Substrate Analogue, 4-Oxo-N,N,N- Trimethylpentanaminium - Orthorhombic space group - Dataset D at 100K
分子名称: (4R)-4-HYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ...
著者Colletier, J.P, Bourgeois, D, Fournier, D, Silman, I, Sussman, J.L, Weik, M.
登録日2007-12-09
公開日2008-07-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Shoot-and-Trap: Use of Specific X-Ray Damage to Study Structural Protein Dynamics by Temperature-Controlled Cryo-Crystallography.
Proc.Natl.Acad.Sci.USA, 105, 2008
6N4R
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CryoEM structure of Nav1.7 VSD2 (deactived state) in complex with the gating modifier toxin ProTx2
分子名称: Beta/omega-theraphotoxin-Tp2a, Fab heavy chain, Fab light chain, ...
著者Xu, H, Rohou, A, Arthur, C.P, Estevez, A, Ciferri, C, Payandeh, J, Koth, C.M.
登録日2018-11-20
公開日2019-01-23
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
Cell, 176, 2019
1EDZ
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STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE
分子名称: 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE
著者Monzingo, A.F, Breksa, A, Ernst, S, Appling, D.R, Robertus, J.D.
登録日2000-01-28
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci., 9, 2000
7O5R
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Crystal structure of holo-SwHPA-Mn (hydroxyketoacid aldolase) from Sphingomonas wittichii RW1
分子名称: BROMIDE ION, MANGANESE (II) ION, POTASSIUM ION, ...
著者Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I.
登録日2021-04-09
公開日2022-10-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Substrate Induced Movement of the Metal Cofactor between Active and Resting State.
Angew.Chem.Int.Ed.Engl., 61, 2022
7P1Z
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Novel GH12 endogluconase from Aspergillus cervinus
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, Glycoside hydrolase, ...
著者Lazarenko, V.A, Rykov, S.V, Nikolaeva, A.Y, Berezina, O.V, Akentyev, F.I.
登録日2021-07-03
公開日2021-07-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Unusual substrate specificity in GH family 12: structure-function analysis of glucanases Bgh12A and Xgh12B from Aspergillus cervinus, and Egh12 from Thielavia terrestris.
Appl.Microbiol.Biotechnol., 106, 2022
7T2F
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Solution structure of the model HEEH mini protein homodimer HEEH_TK_rd5_0341
分子名称: HEEH mini protein HEEH_TK_rd5_0341
著者Lemak, A, Houliston, S, Kim, T.-E, Martel, C, Rocklin, G.J, Arrowsmith, C.H.
登録日2021-12-04
公開日2022-10-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SR6
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Human Endogenous Retrovirus (HERV-K) reverse transcriptase ternary complex with dsDNA template Primer and dNTP
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ...
著者Baldwin, E.T, Nichols, C.
登録日2021-11-08
公開日2022-07-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TB1
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Crystal structure of STUB1 with a macrocyclic peptide
分子名称: 1,3-bis(sulfanyl)propan-2-one, ALA-CYS-SER-SER-ILE-TRP-CYS-PRO-ASP-GLY, E3 ubiquitin-protein ligase CHIP
著者Bahmanjah, S, Klein, D.J.
登録日2021-12-21
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.785 Å)
主引用文献Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1.
J.Med.Chem., 2022
7SLT
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Protease inhibitors variant, CTI-homolog pacifastin
分子名称: GLYCEROL, Protease inhibitor LCMI-II
著者Gewe, M.M, Strong, R.K.
登録日2021-10-24
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
7SND
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Pacifastin related protease inhibitors
分子名称: GLYCEROL, PHOSPHATE ION, Pacifastin-related peptide
著者Gewe, M.M, Strong, R.K.
登録日2021-10-27
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
6NNV
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PD-L1 IgV domain complex with macro-cyclic peptide
分子名称: Programmed cell death 1 ligand 1, macrocyclic peptide
著者Zhao, B, Perry, E.
登録日2019-01-15
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
7UG6
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Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W.
登録日2022-03-24
公開日2022-12-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome.
Nat.Struct.Mol.Biol., 30, 2023
2VT6
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BU of 2vt6 by Molmil
Native Torpedo californica acetylcholinesterase collected with a cumulated dose of 9400000 Gy
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, CHLORIDE ION, ...
著者Colletier, J.P, Bourgeois, D, Sanson, B, Fournier, D, Sussman, J.L, Silman, I, Weik, M.
登録日2008-05-09
公開日2008-07-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Shoot-and-Trap: Use of Specific X-Ray Damage to Study Structural Protein Dynamics by Temperature-Controlled Cryo-Crystallography.
Proc.Natl.Acad.Sci.USA, 105, 2008
4JDJ
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Crystal structure of Serine/threonine-protein kinase PAK 4 F461V mutant in complex with Paktide T peptide substrate
分子名称: Paktide T, Serine/threonine-protein kinase PAK 4
著者Ha, B.H, Boggon, T.J.
登録日2013-02-25
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.
Mol.Cell, 53, 2014
4JRY
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Crystal Structure of SB47 TCR-HLA B*3505-LPEP complex
分子名称: Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2013-03-22
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule.
J.Biol.Chem., 288, 2013
7Q2X
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Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (Form I)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Condensin complex subunit 1, ...
著者Lee, B.-G, Rhodes, J, Lowe, J.
登録日2021-10-26
公開日2022-03-23
最終更新日2022-04-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Clamping of DNA shuts the condensin neck gate.
Proc.Natl.Acad.Sci.USA, 119, 2022
7PC4
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The PDZ domain of SNTB1 complexed with the PDZ-binding motif of HTLV1-TAX1
分子名称: 1,2-ETHANEDIOL, Beta-1-syntrophin,Annexin A2, CALCIUM ION, ...
著者Cousido-Siah, A, Trave, G, Gogl, G.
登録日2021-08-03
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC5
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The third PDZ domain of PDZD7 complexed with the PDZ-binding motif of EXOC4
分子名称: CALCIUM ION, Exocyst complex component 4, GLYCEROL, ...
著者Cousido-Siah, A, Trave, G, Gogl, G.
登録日2021-08-03
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PCB
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The PDZ domain of SNX27 fused with ANXA2
分子名称: CALCIUM ION, GLYCEROL, Sorting nexin-27,Annexin A2
著者Cousido-Siah, A, Trave, G, Gogl, G.
登録日2021-08-03
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC7
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The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN
分子名称: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ...
著者Cousido-Siah, A, Trave, G, Gogl, G.
登録日2021-08-03
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC9
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The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1
分子名称: CALCIUM ION, Protein Tax-1, Synaptojanin-2-binding protein,Annexin A2
著者Cousido-Siah, A, Trave, G, Gogl, G.
登録日2021-08-03
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022
7PC3
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The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1
分子名称: CALCIUM ION, Disks large homolog 1,Annexin A2, GLYCEROL, ...
著者Cousido-Siah, A, Trave, G, Gogl, G.
登録日2021-08-03
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A scalable strategy to solve structures of PDZ domains and their complexes.
Acta Crystallogr D Struct Biol, 78, 2022

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