5UP5
| Solution structure of the de novo mini protein EHEE_rd1_0284 | 分子名称: | EHEE_rd1_0284 | 著者 | Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. | 登録日 | 2017-02-01 | 公開日 | 2017-07-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Global analysis of protein folding using massively parallel design, synthesis, and testing. Science, 357, 2017
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5KAY
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6XY1
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6XY0
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6XXZ
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5UP1
| Solution structure of the de novo mini protein EEHEE_rd3_1049 | 分子名称: | EEHEE_rd3_1049 | 著者 | Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. | 登録日 | 2017-02-01 | 公開日 | 2017-07-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Global analysis of protein folding using massively parallel design, synthesis, and testing. Science, 357, 2017
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8UZL
| Designed Transmembrane beta-barrel- TMB10_163 | 分子名称: | Designed Transmembrane beta-barrel TMB10_163, HEXANE-1,6-DIOL | 著者 | Bera, A.K, Lemma, S.B, Kang, A, Baker, D. | 登録日 | 2023-11-15 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Sculpting conducting nanopore size and shape through de novo protein design Science, 2024
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1KYC
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1HQJ
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7TYD
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8VSW
| 4-MERCAPTOPHENOL-ALPHA3C | 分子名称: | 4-mercaptophenol-alpha3C protein, 4-sulfanylphenol | 著者 | Tommos, C. | 登録日 | 2024-01-24 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Switching the proton-coupled electron transfer mechanism for non-canonical tyrosine residues in a de novo protein. Chem Sci, 15, 2024
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6VFL
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7N1K
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2KPO
| Solution NMR structure of de novo designed rossmann 2x2 fold protein, Northeast Structural Genomics Consortium target OR16 | 分子名称: | rossmann 2x2 fold protein | 著者 | Liu, G, Koga, R, Koga, N, Xiao, R, Hamilton, K, Ciccosanti, C, Acton, T.B, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-17 | 公開日 | 2009-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of denovo designed rossmann 2x2 fold protein, Northeast Structural Genomics Consortium target OR16 To be Published
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6OHH
| Structure of EF1p2_mFAP2b bound to DFHBI | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, CALCIUM ION, EF1p2_mFAP2b | 著者 | Doyle, L.A, Stoddard, B.L. | 登録日 | 2019-04-05 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Incorporation of sensing modalities into de novo designed fluorescence-activating proteins Nat Commun, 12, 2021
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4D8H
| Crystal structure of Symfoil-4P/PV2: de novo designed beta-trefoil architecture with symmetric primary structure, primitive version 2 (6xLeu / PV1) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo protein | 著者 | Blaber, M, Longo, L. | 登録日 | 2012-01-10 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein. Proc.Natl.Acad.Sci.USA, 110, 2013
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3LJM
| Structure of de novo designed apo peptide coil SER L9C | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, COIL SER L9C, ... | 著者 | Chakraborty, S. | 登録日 | 2010-01-26 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Structural comparisons of apo- and metalated three-stranded coiled coils clarify metal binding determinants in thiolate containing designed peptides. J.Am.Chem.Soc., 132, 2010
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6MCD
| Crystal Structure of tris-thiolate Pb(II) complex with adjacent water in a de novo Three Stranded Coiled Coil Peptide | 分子名称: | LEAD (II) ION, Pb(II)(GRAND Coil Ser L12CL16A)-, ZINC ION | 著者 | Tolbert, A.E, Ruckthong, L, Stuckey, J.A, Pecoraro, V.L. | 登録日 | 2018-08-31 | 公開日 | 2020-03-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Heteromeric three-stranded coiled coils designed using a Pb(II)(Cys)3template mediated strategy. Nat.Chem., 12, 2020
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8QAA
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8QAE
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8QAG
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8QAH
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2LSE
| Solution NMR Structure of De Novo Designed Four Helix Bundle Protein, Northeast Structural Genomics Consortium (NESG) Target OR188 | 分子名称: | Four Helix Bundle Protein | 著者 | Sathyamoorthy, B, Pulavarti, S, Murphy, G, Mills, J.L, Eletski, A, Der, B.S, Machius, M.C, Kuhlman, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-04-28 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of a Denovo Design Four Helix Bundle Protein, Northeast Structural Genomics Consortium Target OR188 To be Published
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4C5D
| Crystal structure of Bcl-xL in complex with benzoylurea compound (42) | 分子名称: | (R)-3-(4-BROMOBENZYLTHIO)-2-(3-(3-((2,4-DIFLUOROPHENYL)ETHYNYL)BENZOYL)-3-PROPYLUREIDO)PROPANOIC ACID, 1,2-ETHANEDIOL, BCL-2-LIKE PROTEIN 1, ... | 著者 | Roy, M.J, Brady, R.M, Lessene, G, Colman, P.M, Czabotar, P.E. | 登録日 | 2013-09-11 | 公開日 | 2014-02-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | De-Novo Designed Library of Benzoylureas as Inhibitors of Bcl-Xl: Synthesis, Structural and Biochemical Characterization. J.Med.Chem., 57, 2014
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4C52
| Crystal structure of Bcl-xL in complex with benzoylurea compound (39b) | 分子名称: | (R)-2-(3-(3-((2,4-DIFLUOROPENYL)ETHYNYL)BENZOYL)-3-PROPYLUREIDO)-3-(ISOBUTYLTHIO) PROPANOIC ACID, 1,2-ETHANEDIOL, BCL-2-LIKE PROTEIN 1, ... | 著者 | Roy, M.J, Brady, R.M, Lessene, G, Colman, P.M, Czabotar, P.E. | 登録日 | 2013-09-10 | 公開日 | 2014-02-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | 主引用文献 | De-Novo Designed Library of Benzoylureas as Inhibitors of Bcl-Xl: Synthesis, Structural and Biochemical Characterization. J.Med.Chem., 57, 2014
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