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7YSG
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Cryo-EM structure of human FcmR bound to sIgM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
著者Li, Y, Shen, H, Xiao, J.
登録日2022-08-12
公開日2023-02-01
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
7YTC
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Cryo-EM structure of human FcmR bound to IgM-Fc/J
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ...
著者Li, Y, Shen, H, Xiao, J.
登録日2022-08-14
公開日2023-02-01
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
7ZLG
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BU of 7zlg by Molmil
Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with acceptor peptide and bound to CMT2-Fab and anti-Fab nanobody
分子名称: Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ...
著者Bloch, J.S, Mukherjee, S, Mao, R, Irobalieva, R, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P.
登録日2022-04-15
公開日2023-01-11
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
7ZLJ
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BU of 7zlj by Molmil
Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and acceptor peptide, bound to CMT2-Fab and anti-Fab nanobody
分子名称: Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ...
著者Bloch, J.S, Mao, R, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P.
登録日2022-04-15
公開日2023-01-11
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
7ZLI
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Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody
分子名称: Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ...
著者Bloch, J.S, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P.
登録日2022-04-15
公開日2023-01-11
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Nat.Chem.Biol., 19, 2023
8A64
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cryoEM structure of the catalytically inactive EndoS from S. pyogenes in complex with the Fc region of immunoglobulin G1.
分子名称: Endo-beta-N-acetylglucosaminidase F2, Immunoglobulin gamma-1 heavy chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Trastoy, B, Cifuente, J.O, Du, J.J, Sundberg, E.J, Guerin, M.E.
登録日2022-06-16
公開日2023-04-05
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases.
Nat Commun, 14, 2023
7RNO
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BU of 7rno by Molmil
Model of the Ac-6-FP/hpMR1/bB2m/TAPBPR complex from integrated docking, NMR and restrained MD
分子名称: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ...
著者McShan, A.C, Sgourakis, N.G.
登録日2021-07-29
公開日2022-05-11
最終更新日2022-08-10
実験手法SOLUTION NMR
主引用文献TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules.
Nat.Chem.Biol., 18, 2022
7RYN
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CD1a-sulfatide-gdTCR complex
分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2021-08-25
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors.
Nat Commun, 13, 2022
7RYO
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CD1a-dideoxymycobactin-gdTCR complex
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, SULFATE ION, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2021-08-25
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors.
Nat Commun, 13, 2022
7RYM
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CD1a-endo-gdTCR complex
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2021-08-25
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors.
Nat Commun, 13, 2022
7RYL
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BU of 7ryl by Molmil
T cell receptor CO3
分子名称: 1,2-ETHANEDIOL, SULFATE ION, T cell receptor delta variable 1,T cell receptor alpha chain constant, ...
著者Wegrecki, M, Le Nours, J, Rossjohn, J.
登録日2021-08-25
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors.
Nat Commun, 13, 2022
4D9Q
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BU of 4d9q by Molmil
Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D
分子名称: Anti-Factor D, heavy chain, light chain, ...
著者Murray, J.M, Wiesmann, C.
登録日2012-01-11
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Inhibiting alternative pathway complement activation by targeting the factor d exosite.
J.Biol.Chem., 287, 2012
4D9L
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BU of 4d9l by Molmil
Fab structure of anti-HIV-1 gp120 V2 mAb 697
分子名称: Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697
著者Pan, R.M, Kong, X.P.
登録日2012-01-11
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.485 Å)
主引用文献Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals.
Virology, 427, 2012
4CKD
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BU of 4ckd by Molmil
Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4.
分子名称: BETA-GALACTOSIDASE, SCFV13R4 ANTIBODY FV HEAVY CHAIN, SCFV13R4 ANTIBODY FV LIGHT CHAIN
著者Vinothkumar, K.R, McMullan, G, Henderson, R.
登録日2014-01-03
公開日2014-01-15
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Molecular Mechanism of Antibody-Mediated Activation of Beta-Galactosidase.
Structure, 22, 2014
7TY0
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BU of 7ty0 by Molmil
Nipah Virus attachment (G) glycoprotein ectodomain in complex with nAH1.3 neutralizing antibody Fab fragment (local refinement of the stalk region)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, Z.Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-02-10
公開日2022-03-09
最終更新日2022-04-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Architecture and antigenicity of the Nipah virus attachment glycoprotein.
Science, 375, 2022
4BFI
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BU of 4bfi by Molmil
Structure of the complex of the extracellular portions of mouse CD200R and mouse CD200
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1, ...
著者Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N.
登録日2013-03-19
公開日2013-05-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution
Structure, 21, 2013
7TJ8
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BU of 7tj8 by Molmil
Cryo-EM structure of the human Nax channel in complex with beta3 solved in nanodiscs
分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Noland, C.L, Kschonsak, M, Ciferri, C, Payandeh, J.
登録日2022-01-14
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.
Nat Commun, 13, 2022
7TJ9
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Cryo-EM structure of the human Nax channel in complex with beta3 solved in GDN
分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Noland, C.L, Kschonsak, M, Ciferri, C, Payandeh, J.
登録日2022-01-14
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.
Nat Commun, 13, 2022
4DAG
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BU of 4dag by Molmil
Structure of the Human Metapneumovirus Fusion Protein with Neutralizing Antibody Identifies a Pneumovirus Antigenic Site
分子名称: Fusion glycoprotein F0, Neutralizing Antibody DS7 heavy chain, Neutralizing Antibody DS7 light chain, ...
著者Jardetzky, T.S, Wen, X.
登録日2012-01-12
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.3904 Å)
主引用文献Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site.
Nat.Struct.Mol.Biol., 19, 2012
4EN3
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Crystal structure of a human Valpha24(-) NKT TCR in complex with CD1d/alpha-galactosylceramide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Lopez-Sagaseta, J, Adams, E.J.
登録日2012-04-12
公開日2012-10-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.568 Å)
主引用文献The Molecular Basis for Recognition of CD1d/alpha-Galactosylceramide by a Human Non-Valpha24 T Cell Receptor Struct. Title
Plos Biol., 10, 2012
4D3C
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BU of 4d3c by Molmil
Crystal structure of the NK1 domain of HGF in complex with anti-HGF monoclonal antibody SFN68.
分子名称: HEPATOCYTE GROWTH FACTOR, SFN68 FAB
著者Kang, Y.J, Kim, K.L, Cho, H.S, Chung, J.H.
登録日2014-10-21
公開日2016-01-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist.
to be published
4F37
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Structure of the tethered N-terminus of Alzheimer's disease A peptide
分子名称: Colicin-E7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, Im7 immunity protein
著者Nisbet, R.M, Nuttall, S.D, Caine, J.M, Rober, R, Hittaki, M, Pearce, L.A, Davydova, N, Masters, C.L, Varghese, J.N, Streltsov, V.A.
登録日2012-05-09
公開日2013-05-15
最終更新日2014-09-03
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013
3V4U
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Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-12-15
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3V52
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Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ...
著者Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H.
登録日2011-12-15
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3VRL
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Crystal structure of BMJ4 p24 capsid protein in complex with A10F9 Fab
分子名称: A10F9 Fab heavy chain, A10F9 Fab light chain, Gag protein
著者Gu, Y, Cao, F, Li, S, Yuan, Y.A, Xia, N.
登録日2012-04-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the HIV-1 capsid protein p24 in complex with the broad-spectrum antibody A10F9
To be Published

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件を2024-07-10に公開中

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