PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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8K00	RPA70N-MRE11 fusion 分子名称: Double-strand break repair protein MRE11, Replication protein A 70 kDa DNA-binding subunit 著者 Fu, W.M, Wu, Y.Y, Zhou, C. 登録日 2023-07-07 公開日 2023-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural characterization of human RPA70N association with DNA damage response proteins. Elife, 12, 2023
3FDQ	Recognition of AT-rich DNA binding sites by the MogR Repressor 分子名称: 5'-D(*AP*TP*TP*TP*TP*TP*TP*AP*AP*AP*AP*AP*AP*AP*T)-3', 5'-D(*TP*AP*TP*TP*TP*TP*TP*TP*TP*AP*AP*AP*AP*AP*A)-3', Motility gene repressor mogR 著者 Shen, A, Higgins, D.E, Panne, D. 登録日 2008-11-26 公開日 2009-06-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Recognition of AT-Rich DNA Binding Sites by the MogR Repressor. Structure, 17, 2009
8V7G	Human DNA polymerase eta-DNA-gemC-ended primer-dAMPNPP ternary complex with Mg2+ 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(U7B))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ To Be Published
1GCB	GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL) 分子名称: GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ... 著者 Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C. 登録日 1995-07-18 公開日 1995-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science, 269, 1995
7BZH	Solution structure of a DNA binding protein from Sulfolobus islandicus 分子名称: Sul7s 著者 Zhang, Z, Liu, X. 登録日 2020-04-28 公開日 2021-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A Novel Family of Winged-Helix Single-Stranded DNA-Binding Proteins from Archaea. Int J Mol Sci, 23, 2022
1BIX	THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES 分子名称: AP ENDONUCLEASE 1, PLATINUM (II) ION, SAMARIUM (III) ION 著者 Gorman, M.A, Morera, S, Rothwell, D.G, De La Fortelle, E, Mol, C.D, Tainer, J.A, Hickson, I.D, Freemont, P.S. 登録日 1998-06-19 公開日 1999-06-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J., 16, 1997
5UM9	Flap endonuclease 1 (FEN1) D86N with 5'-flap substrate DNA and Sm3+ 分子名称: DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), DNA (5'-D(P*TP*CP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*GP*T)-3'), ... 著者 Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. 登録日 2017-01-26 公開日 2017-06-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.805 Å) 主引用文献 Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nat Commun, 8, 2017
4NDH	Human Aprataxin (Aptx) bound to DNA, AMP, and Zn - product complex 分子名称: 5'-D(P*GP*TP*TP*CP*TP*AP*GP*AP*AP*C)-3', ADENOSINE MONOPHOSPHATE, Aprataxin, ... 著者 Schellenberg, M.J, Tumbale, P.S, Williams, R.S. 登録日 2013-10-26 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.848 Å) 主引用文献 Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity. Nature, 506, 2013
4KPE	Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate 分子名称: (7aR,8R)-8-amino-4-cyclopropyl-12-fluoro-1-oxo-4,7,7a,8,9,10-hexahydro-1H-pyrrolo[1',2':1,7]azepino[2,3-h]quinoline-2-carboxylic acid, DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, ... 著者 Laponogov, I, Pan, X.-S, Vesekov, D.A, Cirz, R.T, Wagman, A.S, Moser, H.E, Fisher, L.M, Sanderson, M.R. 登録日 2013-05-13 公開日 2014-11-26 最終更新日 2020-01-29 実験手法 X-RAY DIFFRACTION (3.43 Å) 主引用文献 Exploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolones. Open Biol, 6, 2016
2IUU	P. aeruginosa FtsK motor domain, hexamer 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA TRANSLOCASE FTSK 著者 Massey, T.H, Mercogliano, C.P, Yates, J, Sherratt, D.J, Lowe, J. 登録日 2006-06-07 公開日 2006-08-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Double-Stranded DNA Translocation: Structure and Mechanism of Hexameric Ftsk Mol.Cell, 23, 2006
7NB0	Structure of the DNA-binding domain of SEPALLATA 3 分子名称: Developmental protein SEPALLATA 3 著者 Zubieta, C, Nanao, M.H. 登録日 2021-01-25 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors. Nat Commun, 12, 2021
3V7J	Co-crystal structure of Wild Type Rat polymerase beta: Enzyme-DNA binary complex 分子名称: CHLORIDE ION, DNA (5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*AP*AP*CP*TP*CP*AP*CP*AP*TP*A)-3'), ... 著者 Rangarajan, S, Jaeger, J. 登録日 2011-12-21 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystallographic studies of K72E mutant DNA polymerase explain loss of lyase function and reveal changes in the overall conformational state of the polymerase domain To be Published
128D	MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG) COMPLEXED WITH HOECHST 33258 分子名称: 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3') 著者 Sriram, M, Van Der Marel, G.A, Roelen, H.L.P.F, Van Boom, J.H, Wang, A.H.-J. 登録日 1993-06-30 公開日 1994-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342. EMBO J., 11, 1992
130D	MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG) COMPLEXED WITH HOECHST 33342 分子名称: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3') 著者 Sriram, M, Van Der Marel, G.A, Roelen, H.L.P.F, Van Boom, J.H, Wang, A.H.-J. 登録日 1993-06-30 公開日 1994-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342. EMBO J., 11, 1992
2JXH	Solution Structure of DNA binding domain of Proline Utilization A (PutA) for Psuedomonas putida 分子名称: Proline dehydrogenase 著者 Halouska, S, Zhou, Y, Becker, D, Powers, R. 登録日 2007-11-19 公開日 2008-10-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Pseudomonas putida protein PpPutA45 and its DNA complex Proteins, 75, 2008
7N3Z	Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA-(apurinic or apyrimidinic site) endonuclease 2, ... 著者 Wojtaszek, J.L, Wallace, B.D, Williams, R.S. 登録日 2021-06-02 公開日 2022-09-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2. Cell Rep, 41, 2022
1JFI	Crystal Structure of the NC2-TBP-DNA Ternary Complex 分子名称: 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ... 著者 Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2001-06-20 公開日 2001-07-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. Cell(Cambridge,Mass.), 106, 2001
6SEH	Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease 分子名称: Structure-specific endonuclease subunit SLX1, Structure-specific endonuclease subunit SLX4, ZINC ION 著者 Gaur, V, Zajko, W, Nirwal, S, Szlachcic, A, Gapinska, M, Nowotny, M. 登録日 2019-07-30 公開日 2019-09-25 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease. Nucleic Acids Res., 47, 2019
1JK2	Zif268 D20A mutant bound to the GCT DNA site 分子名称: 5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*CP*CP*CP*AP*CP*GP*C)-3', ZIF268, ... 著者 Miller, J.C, Pabo, C.O. 登録日 2001-07-11 公開日 2001-10-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition. J.Mol.Biol., 313, 2001
5AGU	The sliding clamp of Mycobacterium tuberculosis in complex with a natural product. 分子名称: (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA POLYMERASE III SUBUNIT BETA, ... 著者 Lukat, P, Kling, A, Heinz, D.W, Mueller, R. 登録日 2015-02-03 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.173 Å) 主引用文献 Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins. Science, 348, 2015
5AH4	The sliding clamp of Mycobacterium smegmatis in complex with a natural product. 分子名称: CYCLOHEXYL GRISELIMYCIN, DNA POLYMERASE III SUBUNIT BETA, SODIUM ION 著者 Lukat, P, Kling, A, Heinz, D.W, Mueller, R. 登録日 2015-02-04 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.313 Å) 主引用文献 Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins. Science, 348, 2015
8PNC	Transcription factor BARHL2 bound to TAAGT DNA sequence 分子名称: BarH-like 2 homeobox protein, DNA 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2023-06-30 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Transcription factor BARHL2 bound to different DNA sequences To Be Published
8PMV	transcription factor BARHL2 bound to TAAGC DNA sequence 分子名称: BarH-like 2 homeobox protein, DNA 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2023-06-29 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 transcription factor BARHL2 bound to DNA sequences To Be Published
7QW7	Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate fully methylated DNA duplex 分子名称: Fully methylated DNA duplex, Modification methylase BseCI, S-ADENOSYL-L-HOMOCYSTEINE 著者 Mitsikas, D.A, Kouyianou, K, Kotsifaki, D, Providaki, M, Bouriotis, V, Glykos, N.M, Kokkinidis, M. 登録日 2022-01-24 公開日 2023-01-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus. To Be Published
7QW5	Adenine-specific DNA methyltransferase M.BseCI complexed with AdoHcy and cognate unmethylated DNA duplex 分子名称: Modification methylase BseCI, S-ADENOSYL-L-HOMOCYSTEINE, Unmethylated DNA duplex 著者 Mitsikas, D.A, Kouyianou, K, Kotsifaki, D, Providaki, M, Bouriotis, V, Glykos, N.M, Kokkinidis, M. 登録日 2022-01-24 公開日 2023-01-25 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus. To Be Published

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