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1K9A
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Crystal structure analysis of full-length carboxyl-terminal Src kinase at 2.5 A resolution
分子名称: Carboxyl-terminal Src kinase
著者Ogawa, A, Takayama, Y, Nagata, A, Chong, K.T, Takeuchi, S, Sakai, H, Nakagawa, A, Nada, S, Okada, M, Tsukihara, T.
登録日2001-10-28
公開日2002-03-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the carboxyl-terminal Src kinase, Csk.
J.Biol.Chem., 277, 2002
1L96
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STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Dixon, M, Shewchuk, L, Matthews, B.W.
登録日1992-02-11
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3-->Pro.
J.Mol.Biol., 227, 1992
1KIS
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TAR-TAR "KISSING" HAIRPIN COMPLEX DERIVED FROM THE HIV GENOME, NMR, 1 STRUCTURE
分子名称: RNA (5'-R(*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)-3'), RNA (5'-R(*GP*CP*UP*GP*UP*UP*CP*CP*CP*AP*GP*AP*CP*AP*GP*C)-3')
著者Chang, K.Y, Tinoco Jr, I.
登録日1997-06-11
公開日1997-10-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The structure of an RNA "kissing" hairpin complex of the HIV TAR hairpin loop and its complement.
J.Mol.Biol., 269, 1997
1L97
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STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO
分子名称: T4 LYSOZYME
著者Dixon, M, Shewchuk, L, Matthews, B.W.
登録日1992-02-11
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3-->Pro.
J.Mol.Biol., 227, 1992
1L8Z
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Solution structure of HMG box 5 in human upstream binding factor
分子名称: upstream binding factor 1
著者Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y.
登録日2002-03-22
公開日2002-06-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
1PSB
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Solution structure of calcium loaded S100B complexed to a peptide from N-Terminal regulatory domain of NDR kinase.
分子名称: Ndr Ser/Thr kinase-like protein, S-100 protein, beta chain
著者Bhattacharya, S, Large, E, Heizmann, C.W, Hemmings, B, Chazin, W.J.
登録日2003-06-21
公開日2003-12-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Ca(2+)/S100B/NDR Kinase Peptide Complex: Insights into S100 Target Specificity and Activation of the Kinase.
Biochemistry, 42, 2003
8AYM
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Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand JNJ-55511118
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, ...
著者Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.H.
登録日2022-09-02
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics.
Nat Commun, 14, 2023
8AYN
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Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand LY3130481
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[(1~{S})-1-[1-[5-(2-hydroxyethyloxy)pyridin-2-yl]pyrazol-3-yl]ethyl]-3~{H}-1,3-benzothiazol-2-one, ...
著者Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.H.
登録日2022-09-02
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics.
Nat Commun, 14, 2023
8AYL
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Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand JNJ-61432059
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 5-[2-(4-fluorophenyl)-7-(4-oxidanylpiperidin-1-yl)pyrazolo[1,5-c]pyrimidin-3-yl]-1,3-dihydroindol-2-one, ...
著者Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.
登録日2022-09-02
公開日2023-04-19
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics.
Nat Commun, 14, 2023
1L8Y
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Solution structure of HMG box 5 in human upstream binding factor
分子名称: upstream binding factor 1
著者Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y.
登録日2002-03-22
公開日2002-06-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor
Biochemistry, 42, 2003
1L3R
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Crystal Structure of a Transition State Mimic of the Catalytic Subunit of cAMP-dependent Protein Kinase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ...
著者Madhusudan, Akamine, P, Xuong, N.-H, Taylor, S.S.
登録日2002-02-28
公開日2002-03-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase.
Nat.Struct.Biol., 9, 2002
1L7C
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alpha-catenin fragment, residues 385-651
分子名称: Alpha E-catenin
著者Pokutta, S, Drees, F, Takai, Y, Nelson, W.J, Weis, W.I.
登録日2002-03-14
公開日2002-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin.
J.Biol.Chem., 277, 2002
1KJW
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BU of 1kjw by Molmil
SH3-Guanylate Kinase Module from PSD-95
分子名称: POSTSYNAPTIC DENSITY PROTEIN 95, SULFATE ION
著者McGee, A.W, Dakoji, S.R, Olsen, O, Bredt, D.S, Lim, W.A, Prehoda, K.E.
登録日2001-12-05
公開日2002-01-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins
Mol.Cell, 8, 2001
1M5I
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BU of 1m5i by Molmil
Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC
分子名称: APC protein
著者Tickenbrock, L, Cramer, J, Vetter, I.R, Mueller, O.
登録日2002-07-09
公開日2002-11-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1).
J.Biol.Chem., 277, 2002
9FMM
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BU of 9fmm by Molmil
Structure of human ACE2 in complex with a fluorinated small molecule inhibitor
分子名称: (2~{S})-2-[[(2~{S})-3-[3-[(3-chloranyl-5-fluoranyl-phenyl)methyl]imidazol-4-yl]-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-4-methyl-pentanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Benoit, R.B, Rodrigues, M.J, Wieser, M.M.
登録日2024-06-06
公開日2024-07-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2.
Eur J Nucl Med Mol Imaging, 2024
8YS9
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Crystal structure of Phosphatidylethanolamine N-methyltransferase from R. thermophilum complexed with DMPE and SAH
分子名称: DODECYL-BETA-D-MALTOSIDE, L(+)-TARTARIC ACID, Phosphatidylethanolamine N-methyltransferase/phosphatidyl-N-methylethanolamine N-methyltransferase, ...
著者Kim, J, Salsabila, S.D.
登録日2024-03-22
公開日2024-10-16
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural insights into phosphatidylethanolamine N -methyltransferase PmtA mediating bacterial phosphatidylcholine synthesis.
Sci Adv, 10, 2024
9EM1
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Human pyridoxal phosphatase in complex with 7,8-dihydroxyflavone and phosphate
分子名称: 7,8-bis(oxidanyl)-2-phenyl-chromen-4-one, Chronophin, GLYCEROL, ...
著者Brenner, M, Gohla, A, Schindelin, H.
登録日2024-03-07
公開日2024-06-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase.
Elife, 13, 2024
9BRT
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Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9FBV
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70S Escherichia coli ribosome with P-site initiatior tRNA.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ...
著者Koller, T.O, Wilson, D.N.
登録日2024-05-14
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
Biorxiv, 2024
9BRB
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Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 1
分子名称: ATPase H+-transporting V1 subunit D, ATPase, H+ transporting, ...
著者Coupland, C.E, Rubinstein, J.L.
登録日2024-05-11
公開日2024-06-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles.
Science, 385, 2024
9BPA
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Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form
分子名称: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-05-07
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024
8YG8
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The early intermediate structure of baculovirus fusion protein GP64
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Major envelope glycoprotein
著者Du, D, Guo, J, Li, S.
登録日2024-02-26
公開日2024-09-11
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural transition of GP64 triggered by a pH-sensitive multi-histidine switch.
Nat Commun, 15, 2024
9BP9
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Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form
分子名称: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-05-07
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM.
Nat Commun, 15, 2024
9RNT
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RIBONUCLEASE T1 WITH FREE RECOGNITION AND CATALYTIC SITE: CRYSTAL STRUCTURE ANALYSIS AT 1.5 ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, RIBONUCLEASE T1
著者Martinez-Oyanedel, J, Heinemann, U, Saenger, W.
登録日1991-09-25
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Ribonuclease T1 with free recognition and catalytic site: crystal structure analysis at 1.5 A resolution.
J.Mol.Biol., 222, 1991
9BRA
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Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles
分子名称: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
著者Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
登録日2024-05-11
公開日2024-06-19
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024

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