1K9A
| Crystal structure analysis of full-length carboxyl-terminal Src kinase at 2.5 A resolution | 分子名称: | Carboxyl-terminal Src kinase | 著者 | Ogawa, A, Takayama, Y, Nagata, A, Chong, K.T, Takeuchi, S, Sakai, H, Nakagawa, A, Nada, S, Okada, M, Tsukihara, T. | 登録日 | 2001-10-28 | 公開日 | 2002-03-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the carboxyl-terminal Src kinase, Csk. J.Biol.Chem., 277, 2002
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1L96
| STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | 著者 | Dixon, M, Shewchuk, L, Matthews, B.W. | 登録日 | 1992-02-11 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3-->Pro. J.Mol.Biol., 227, 1992
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1KIS
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1L97
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1L8Z
| Solution structure of HMG box 5 in human upstream binding factor | 分子名称: | upstream binding factor 1 | 著者 | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | 登録日 | 2002-03-22 | 公開日 | 2002-06-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor Biochemistry, 42, 2003
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1PSB
| Solution structure of calcium loaded S100B complexed to a peptide from N-Terminal regulatory domain of NDR kinase. | 分子名称: | Ndr Ser/Thr kinase-like protein, S-100 protein, beta chain | 著者 | Bhattacharya, S, Large, E, Heizmann, C.W, Hemmings, B, Chazin, W.J. | 登録日 | 2003-06-21 | 公開日 | 2003-12-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Ca(2+)/S100B/NDR Kinase Peptide Complex: Insights into S100 Target Specificity and Activation of the Kinase. Biochemistry, 42, 2003
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8AYM
| Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand JNJ-55511118 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, ... | 著者 | Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.H. | 登録日 | 2022-09-02 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics. Nat Commun, 14, 2023
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8AYN
| Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand LY3130481 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[(1~{S})-1-[1-[5-(2-hydroxyethyloxy)pyridin-2-yl]pyrazol-3-yl]ethyl]-3~{H}-1,3-benzothiazol-2-one, ... | 著者 | Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.H. | 登録日 | 2022-09-02 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics. Nat Commun, 14, 2023
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8AYL
| Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand JNJ-61432059 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 5-[2-(4-fluorophenyl)-7-(4-oxidanylpiperidin-1-yl)pyrazolo[1,5-c]pyrimidin-3-yl]-1,3-dihydroindol-2-one, ... | 著者 | Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I. | 登録日 | 2022-09-02 | 公開日 | 2023-04-19 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics. Nat Commun, 14, 2023
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1L8Y
| Solution structure of HMG box 5 in human upstream binding factor | 分子名称: | upstream binding factor 1 | 著者 | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | 登録日 | 2002-03-22 | 公開日 | 2002-06-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor Biochemistry, 42, 2003
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1L3R
| Crystal Structure of a Transition State Mimic of the Catalytic Subunit of cAMP-dependent Protein Kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | 著者 | Madhusudan, Akamine, P, Xuong, N.-H, Taylor, S.S. | 登録日 | 2002-02-28 | 公開日 | 2002-03-20 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase. Nat.Struct.Biol., 9, 2002
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1L7C
| alpha-catenin fragment, residues 385-651 | 分子名称: | Alpha E-catenin | 著者 | Pokutta, S, Drees, F, Takai, Y, Nelson, W.J, Weis, W.I. | 登録日 | 2002-03-14 | 公開日 | 2002-06-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin. J.Biol.Chem., 277, 2002
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1KJW
| SH3-Guanylate Kinase Module from PSD-95 | 分子名称: | POSTSYNAPTIC DENSITY PROTEIN 95, SULFATE ION | 著者 | McGee, A.W, Dakoji, S.R, Olsen, O, Bredt, D.S, Lim, W.A, Prehoda, K.E. | 登録日 | 2001-12-05 | 公開日 | 2002-01-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins Mol.Cell, 8, 2001
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1M5I
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9FMM
| Structure of human ACE2 in complex with a fluorinated small molecule inhibitor | 分子名称: | (2~{S})-2-[[(2~{S})-3-[3-[(3-chloranyl-5-fluoranyl-phenyl)methyl]imidazol-4-yl]-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-4-methyl-pentanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Benoit, R.B, Rodrigues, M.J, Wieser, M.M. | 登録日 | 2024-06-06 | 公開日 | 2024-07-17 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2. Eur J Nucl Med Mol Imaging, 2024
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8YS9
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9EM1
| Human pyridoxal phosphatase in complex with 7,8-dihydroxyflavone and phosphate | 分子名称: | 7,8-bis(oxidanyl)-2-phenyl-chromen-4-one, Chronophin, GLYCEROL, ... | 著者 | Brenner, M, Gohla, A, Schindelin, H. | 登録日 | 2024-03-07 | 公開日 | 2024-06-12 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | 7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase. Elife, 13, 2024
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9BRT
| Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9FBV
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9BRB
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9BPA
| Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form | 分子名称: | (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta | 著者 | Ito, F, Li, Z, Chen, X.S. | 登録日 | 2024-05-07 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM. Nat Commun, 15, 2024
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8YG8
| The early intermediate structure of baculovirus fusion protein GP64 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Major envelope glycoprotein | 著者 | Du, D, Guo, J, Li, S. | 登録日 | 2024-02-26 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-18 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structural transition of GP64 triggered by a pH-sensitive multi-histidine switch. Nat Commun, 15, 2024
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9BP9
| Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form | 分子名称: | (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta | 著者 | Ito, F, Li, Z, Chen, X.S. | 登録日 | 2024-05-07 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM. Nat Commun, 15, 2024
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9RNT
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9BRA
| Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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