PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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5EKV	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: 3-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-11-04 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.61 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
5EHC	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: 3-[[(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-7-[(3-chlorophenyl)methyl]-6-oxidanylidene-1~{H}-purin-7-ium-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-10-28 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
7JW9	Ternary cocrystal structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens 分子名称: Alkanesulfonate monooxygenase, FLAVIN MONONUCLEOTIDE, SODIUM ION, ... 著者 Liew, J.J.M, Dowling, D.P. 登録日 2020-08-25 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer. J.Biol.Chem., 297, 2021
5TQC	Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4) 分子名称: 60S ribosomal protein L4-like protein, Transportin-1,Transportin-1 著者 Huber, F.M, Hoelz, A. 登録日 2016-10-23 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Molecular basis for protection of ribosomal protein L4 from cellular degradation. Nat Commun, 8, 2017
2K7S	Human ARNT C-Terminal PAS Domain, 3 Residue IB slip 分子名称: Aryl hydrocarbon receptor nuclear translocator 著者 Evans, M.R, Card, P.B, Gardner, K.H. 登録日 2008-08-20 公開日 2009-01-20 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space Proc.Natl.Acad.Sci.USA, 106, 2009
2HRA	Crystal structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA aminoacylation and nuclear export cofactor Arc1p reveal a novel function for an old fold 分子名称: Glutamyl-tRNA synthetase, cytoplasmic, IODIDE ION 著者 Simader, H, Hothorn, M, Suck, D. 登録日 2006-07-20 公開日 2006-09-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA-aminoacylation and nuclear-export cofactor Arc1p reveal a novel function for an old fold. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
4JUZ	Ternary complex of gamma-OHPDG adduct modified dna (zero primer) with dna polymerase iv and incoming dgtp 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), ... 著者 Banerjee, S, Shanmugam, G, Stone, M.P. 登録日 2013-03-25 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
4JV2	Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming datp 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... 著者 Banerjee, S, Shanmugam, G, Stone, M.P. 登録日 2013-03-25 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
4JV1	Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming dgtp 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... 著者 Banerjee, S, Shanmugam, G, Stone, M.P. 登録日 2013-03-25 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4. Chem.Res.Toxicol., 26, 2013
5X8F	Ternary complex structure of a double mutant I454RA456K of o-Succinylbenzoate CoA Synthetase (MenE) from Bacillus Subtilis bound with AMP and its product analogue OSB-NCoA at 1.76 angstrom 分子名称: 2-succinylbenzoate--CoA ligase, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... 著者 Chen, Y, Guo, Z. 登録日 2017-03-02 公開日 2017-06-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.763 Å) 主引用文献 Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode J. Biol. Chem., 292, 2017
5N74	Microtubule end binding protein complex 分子名称: Karyogamy protein KAR9, Microtubule-associated protein RP/EB family member 1 著者 Kumar, A, Steinmetz, M. 登録日 2017-02-18 公開日 2017-06-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Short Linear Sequence Motif LxxPTPh Targets Diverse Proteins to Growing Microtubule Ends. Structure, 25, 2017
3E1Y	Crystal structure of human eRF1/eRF3 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1 著者 Cheng, Z, Lim, M, Kong, C, Song, H. 登録日 2008-08-05 公開日 2009-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural insights into eRF3 and stop codon recognition by eRF1 Genes Dev., 23, 2009
6TCH	Binary complex of 14-3-3 sigma and a high-affinity non-canonical 9-mer peptide binder 分子名称: 14-3-3 protein sigma, CHLORIDE ION, DLY-NVA-PPN-KCJ-SEP-PPN-B3S-BAL-PPN-LYS, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2019-11-06 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Ultra-large chemical libraries for the discovery of high-affinity peptide binders. Nat Commun, 11, 2020
4I2H	Ternary complex of mouse TdT with ssDNA and AMPcPP 分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2E	Ternary complex of mouse TdT with ssDNA and AMPcPP 分子名称: 5'-D(*AP*AP*AP*AP*A)-3', COBALT (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I27	Ternary complex of mouse TdT with ssDNA and incoming nucleotide 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*T)-3', DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2C	Ternary complex of mouse TdT with ssDNA and AMPcPP 分子名称: 5'-D(*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
8J7R	Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A (J-K-St/eIF4G focused) 分子名称: Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), MAGNESIUM ION 著者 Suzuki, H, Fujiyoshi, Y, Imai, S, Shimada, I. 登録日 2023-04-28 公開日 2023-08-02 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nat Commun, 14, 2023
3CPF	Crystal structure of human eukaryotic translation initiation factor EIF5A 分子名称: Eukaryotic translation initiation factor 5A-1, UNKNOWN ATOM OR ION 著者 Nedyalkova, L, Tong, Y, Tempel, W, Hong, B, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2008-03-31 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2. Proteins, 75, 2009
8UH1	Crystal structure of T. brucei EIF4E6 in complex with EIF4G5 peptide 分子名称: Eukaryotic translation initiation factor 4E type 6, MIF4G domain-containing protein 著者 Guimaraes, B.G, Penteado, R.F. 登録日 2023-10-06 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Structural analysis of the Trypanosoma brucei EIF4E6/EIF4G5 complex reveals details of the interaction between unusual eIF4F subunits. Sci Rep, 14, 2024
4I2B	Ternary complex of mouse TdT with ssDNA and AMPcPP 分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4NH1	Crystal structure of a heterotetrameric CK2 holoenzyme complex carrying the Andante-mutation in CK2beta and consistent with proposed models of autoinhibition and trans-autophosphorylation 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, GLYCEROL, ... 著者 Schnitzler, A, Issinger, O.-G, Niefind, K. 登録日 2013-11-04 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 The Protein Kinase CK2(Andante) Holoenzyme Structure Supports Proposed Models of Autoregulation and Trans-Autophosphorylation J.Mol.Biol., 426, 2014
2XCP	TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8- DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND dCTP - MAGNESIUM FORM 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP *TP*DOC)-3', 5'-D(*TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... 著者 Irimia, A, Egli, M. 登録日 2010-04-24 公開日 2010-09-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Metal Ion Dependence of the Active Site Conformation of the Trans-Lesion DNA Polymerase Dpo4 from Sulfolobus Solfataricus Acta Crystallogr.,Sect.F, 66, 2010
2XCA	TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8- DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND dGTP - MAGNESIUM FORM 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*DOC)-3', 5'-D(*TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP*CP*TP*TP*CP* CP*CP*CP*C)-3', ... 著者 Irimia, A, Egli, M. 登録日 2010-04-20 公開日 2010-09-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Metal Ion Dependence of the Active Site Conformation of the Trans-Lesion DNA Polymerase Dpo4 from Sulfolobus Solfataricus Acta Crystallogr.,Sect.F, 66, 2010
2XC9	BINARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE AND 1, N2-ETHENOGUANINE MODIFIED DNA, MAGNESIUM FORM 分子名称: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*G)-3', 5'-D(*TP*CP*AP*CP*GNEP*GP*AP*AP*TP*CP*CP*TP*TP* CP*CP*CP*CP*C)-3', DNA POLYMERASE IV 著者 Irimia, A, Loukachevitch, L.V, Egli, M. 登録日 2010-04-20 公開日 2010-09-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Metal Ion Dependence of the Active Site Conformation of the Trans-Lesion DNA Polymerase Dpo4 from Sulfolobus Solfataricus Acta Crystallogr.,Sect.F, 66, 2010

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