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8YE9
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Cryo-EM structure of Cas9-sgRNA-A25 complex
分子名称: A25, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER)
著者Zheng, J, Zhu, Y, Huang, Z.
登録日2024-02-22
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Inhibition mechanisms of CRISPR-Cas9 by AcrIIA25.1 and AcrIIA32.
Sci China Life Sci, 67, 2024
8YE6
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Cryo-EM structure of Cas9-sgRNA-A32 complex
分子名称: A32, CRISPR-associated endonuclease Cas9/Csn1, RNA (92-MER)
著者Zheng, J, Zhu, Y, Huang, Z.
登録日2024-02-22
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Inhibition mechanisms of CRISPR-Cas9 by AcrIIA25.1 and AcrIIA32.
Sci China Life Sci, 67, 2024
8YE3
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Cryo-EM structure of human respiratory syncytial virus fusion protein variant
分子名称: Fusion glycoprotein F0
著者Li, Q.M, Su, J.G, Zhang, J, Liang, Y, Shao, S, Li, X.Y, Zhao, Z.X.
登録日2024-02-21
公開日2024-10-02
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation.
Science, 385, 2024
8YE0
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Crystal structure of KgpF prenyltransferase
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LynF/TruF/PatF family peptide O-prenyltransferase, MAGNESIUM ION, ...
著者Hamada, K, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2024-02-21
公開日2024-06-19
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献De Novo Discovery of Pseudo-Natural Prenylated Macrocyclic Peptide Ligands.
Angew.Chem.Int.Ed.Engl., 63, 2024
8YD3
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Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol
分子名称: (2S)-decane-1,2,10-triol, GLYCEROL, Superoxide dismutase [Cu-Zn], ...
著者Aouti, S, Padmanabhan, B.
登録日2024-02-19
公開日2024-08-21
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol
To Be Published
8YBK
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Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-02-14
公開日2024-07-24
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 29, 2024
8YBJ
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Cryo-EM structure of human nucleosome core particle composed of the Widom 601 DNA sequence
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-02-14
公開日2024-07-24
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 29, 2024
8YBF
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Crystal structure of canine distemper virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein
著者Fukuhara, H, Yumoto, K, Sako, M, Kajikawa, M, Ose, T, Hashiguchi, T, Kamishikiryo, J, Maita, N, Kuroki, K, Maenaka, K.
登録日2024-02-13
公開日2024-07-31
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination.
Elife, 12, 2024
8YB7
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SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C3 symmetry)
分子名称: Non-structural protein 4, Papain-like protease nsp3
著者Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T.
登録日2024-02-12
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
8YB5
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SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C6 symmetry)
分子名称: Non-structural protein 4, Papain-like protease nsp3
著者Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T.
登録日2024-02-11
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
8YB4
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Pfr conformer of Arabidopsis thaliana phytochrome B in complex with phytochrome-interacting factor 6
分子名称: 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, phytochrome B, phytochrome-interacting factor 6
著者Wang, Z, Wang, W, Zhao, D, Song, Y, Xu, B, Zhao, J, Wang, J.
登録日2024-02-11
公開日2024-10-02
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor.
Cell, 2024
8YAX
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SARS-CoV-2 DMV nsp3-4 pore complex (full-pore)
分子名称: Non-structural protein 4, Papain-like protease nsp3
著者Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T.
登録日2024-02-10
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
8YAN
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Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound
分子名称: RNA (33-MER), ~{N},~{N}-dimethyl-2-[(1-methyl-9~{H}-pyrido[3,4-b]indol-7-yl)oxy]ethanamine
著者Numata, T, Schneekloth, J.S.
登録日2024-02-09
公開日2024-09-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression.
Biorxiv, 2024
8YAM
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Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound
分子名称: 2-[2-(dimethylamino)ethoxy]xanthen-9-one, RNA (33-MER)
著者Numata, T, Parmar, S, Schneekloth, J.S.
登録日2024-02-09
公開日2024-09-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression.
Biorxiv, 2024
8Y9X
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Crystal structure of the complex of lactoperoxidase with four inorganic substrates, SCN, I, Br and Cl
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, CALCIUM ION, ...
著者Viswanathan, V, Singh, A.K, Pandey, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2024-02-07
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evidence for the order of preference of inorganic substrates in mammalian heme peroxidases: crystal structure of the complex of lactoperoxidase with four inorganic substrates, SCN, I, Br and Cl
To Be Published
8Y9P
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Crystal structure of bacterial activating sulfotransferase SgdX2
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, GLYCEROL, SgdX2
著者Mori, T, Teramoto, T, Kakuta, Y.
登録日2024-02-07
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structure of activating sulfotransferase SgdX2 involved in biosynthesis of secondary metabolite sungeidine.
Biochem.Biophys.Res.Commun., 711, 2024
8Y95
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Structure of NET-NE in Occluded state
分子名称: CHLORIDE ION, Noradrenaline, SODIUM ION, ...
著者Zhang, H, Xu, H.E, Jiang, Y.
登録日2024-02-06
公開日2024-05-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y94
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Structure of Apo human norepinephrine transporter NET
分子名称: Sodium-dependent noradrenaline transporter
著者Zhang, H, Xu, H.E, Jiang, Y.
登録日2024-02-06
公開日2024-05-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y93
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Structure of NET-Amitriptyline in outward-open state
分子名称: Amitriptyline, CHLORIDE ION, SODIUM ION, ...
著者Zhang, H, Xu, E.H, Jiang, Y.
登録日2024-02-06
公開日2024-05-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y92
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structure of NET-Atomoxetine in outward-open state
分子名称: (3R)-N-methyl-3-(2-methylphenoxy)-3-phenyl-propan-1-amine, CHLORIDE ION, SODIUM ION, ...
著者Zhang, H, Xu, E.H, Jiang, Y.
登録日2024-02-06
公開日2024-05-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y91
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Structure of NET-nomifensine in outward-open state
分子名称: (4S)-2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine, CHLORIDE ION, SODIUM ION, ...
著者Zhang, H, Xu, E.H, Jiang, Y.
登録日2024-02-06
公開日2024-05-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y90
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Structure of NET-Nefopam in outward-open state
分子名称: (1S)-5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine, CHLORIDE ION, SODIUM ION, ...
著者Zhang, H, Xu, E.H, Jiang, Y.
登録日2024-02-06
公開日2024-05-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y8Z
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Structure of NET-Maprotiline in outward-open state
分子名称: CHLORIDE ION, SODIUM ION, Sodium-dependent noradrenaline transporter, ...
著者Zhang, H, Xu, E.H, Jiang, Y.
登録日2024-02-06
公開日2024-05-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
8Y8Y
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Crystal structure of the PTPN21 FERM domain
分子名称: CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21
著者Lee, H.S, Ku, B.
登録日2024-02-06
公開日2024-07-10
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural analysis of the FERM domain of human protein tyrosine phosphatase non-receptor type 21.
Acta Crystallogr.,Sect.F, 80, 2024
8Y6V
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Near-atomic structure of icosahedrally averaged jumbo bacteriophage PhiKZ capsid
分子名称: gp119, gp120, gp162, ...
著者Yang, Y, Shao, Q, Guo, M, Han, L, Zhao, X, Wang, A, Li, X, Wang, B, Pan, J, Chen, Z, Fokine, A, Sun, L, Fang, Q.
登録日2024-02-03
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Capsid structure of bacteriophage Phi KZ provides insights into assembly and stabilization of jumbo phages.
Nat Commun, 15, 2024

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件を2024-10-09に公開中

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