8YE6

Cryo-EM structure of Cas9-sgRNA-A32 complex

Summary for 8YE6

• Entry DOI: 10.2210/pdb8ye6/pdb
• EMDB information: 39190
• Descriptor: A32, CRISPR-associated endonuclease Cas9/Csn1, RNA (92-MER) (3 entities in total)
• Functional Keywords: crispr, complex, immune system/rna, immune system-rna complex
• Biological source: Streptococcus; More
• Total number of polymer chains: 3
• Total formula weight: 205227.51

Authors

Zheng, J.,Zhu, Y.,Huang, Z. (deposition date: 2024-02-22, release date: 2024-09-11)

• Primary citation: Zheng, J.,Zhu, Y.,Huang, T.,Gao, W.,He, J.,Huang, Z.; Inhibition mechanisms of CRISPR-Cas9 by AcrIIA25.1 and AcrIIA32.; Sci China Life Sci, 67:1781-1791, 2024; PubMed: 38842649; DOI: 10.1007/s11427-024-2607-8

Experimental method

ELECTRON MICROSCOPY (2.95 Å)