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4FXE
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BU of 4fxe by Molmil
Crystal structure of the intact E. coli RelBE toxin-antitoxin complex
分子名称: Antitoxin RelB, SULFATE ION, mRNA interferase RelE
著者Brodersen, D.E, Boggild, A, Sofos, N.
登録日2012-07-03
公開日2012-08-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7503 Å)
主引用文献The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
Structure, 20, 2012
6HWU
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BU of 6hwu by Molmil
Crystal structure of p38alpha in complex with a photoswitchable 2-Azothiazol-based Inhibitor (compound 2)
分子名称: 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-[(~{E})-phenyldiazenyl]-1,3-thiazol-5-yl]pyridin-2-yl]propanamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Mueller, M.P, Rauh, D.
登録日2018-10-15
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach.
Photochem. Photobiol. Sci., 18, 2019
4RFA
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BU of 4rfa by Molmil
Crystal structure of cyclic nucleotide-binding domain containing protein from Listeria monocytogenes EGD-e
分子名称: Lmo0740 protein
著者Filippova, E.V, Minasov, G, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2014-09-25
公開日2014-10-15
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of cyclic nucleotide-binding domain containing protein from Listeria monocytogenes EGD-e
To be Published
5NGM
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BU of 5ngm by Molmil
2.9S structure of the 70S ribosome composing the S. aureus 100S complex
分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Amunts, A, Yonath, A.
登録日2017-03-18
公開日2017-10-04
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Nat Commun, 8, 2017
3GS7
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BU of 3gs7 by Molmil
Human transthyretin (TTR) complexed with (E)-3-(2-methoxybenzylideneaminooxy)propanoic acid (inhibitor 13)
分子名称: 3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid, Transthyretin
著者Mohamedmohaideen, N.N, Palaninathan, S.K, Orlandini, E, Sacchettini, J.C.
登録日2009-03-26
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis.
Plos One, 4, 2009
5AMT
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BU of 5amt by Molmil
Intracellular growth locus protein E
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, IGLE
著者Robb, C.S, Nano, F.E, Boraston, A.B.
登録日2015-09-01
公開日2016-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Cloning, Expression, Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of Intracellular Growth Locus E (Igle) Protein from Francisella Tularensis Subsp. Novicida.
Acta Crystallogr.,Sect.F, 66, 2010
1YVT
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BU of 1yvt by Molmil
The high salt (phosphate) crystal structure of CO Hemoglobin E (Glu26Lys) at physiological pH (pH 7.35)
分子名称: CARBON MONOXIDE, GLYCEROL, Hemoglobin alpha chain, ...
著者Malashkevich, V.N, Balazs, T.C, Almo, S.C, Hirsch, R.E.
登録日2005-02-16
公開日2006-02-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The high salt (phosphate) crystal structure of CO Hemoglobin E (Glu26Lys) at physiological pH (pH 7.35)
To be Published
5XB6
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BU of 5xb6 by Molmil
Crystal structure of YcjY from E. Coli
分子名称: Uncharacterized protein YcjY
著者Chen, C.F, Gao, Z.Q, Liu, Q.S.
登録日2017-03-16
公開日2018-04-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of YcjY from E. Coli
To Be Published
7X9Z
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BU of 7x9z by Molmil
Thermotoga maritima ferritin variant-Tm-E(G40E) with Co
分子名称: COBALT (II) ION, Ferritin
著者Yu, L, Guanghua, Z.
登録日2022-03-16
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Thermotoga maritima ferritin variant-Tm-E(G40E) with Co
To Be Published
5GQE
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BU of 5gqe by Molmil
Crystal structure of michaelis complex of xylanase mutant (T82A, N127S, and E128H) from Streptomyces olivaceoviridis E-86
分子名称: Beta-xylanase, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ...
著者Suzuki, R, Fujimoto, Z, Kaneko, S, Kuno, A.
登録日2016-08-07
公開日2017-08-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Azidolysis by the Formation of Stable Ser-His Catalytic Dyad in a Glycoside Hydrolase Family 10 Xylanase Mutant
J.Appl.Glyosci., 65, 2019
1MJW
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BU of 1mjw by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D42N
分子名称: INORGANIC PYROPHOSPHATASE, SULFATE ION
著者Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Samygina, V.R, Huber, R.
登録日1997-02-08
公開日1997-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
Biochemistry Mosc., 63, 1998
1MJX
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BU of 1mjx by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D65N
分子名称: INORGANIC PYROPHOSPHATASE, SULFATE ION
著者Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R.
登録日1997-02-08
公開日1997-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
Biochemistry Mosc., 63, 1998
4ERP
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BU of 4erp by Molmil
Crystal structure of a gemcitabine-diphosphate inhibited E. coli class Ia ribonucleotide reductase complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 subunit alpha, ...
著者Zimanyi, C.M, Drennan, C.L.
登録日2012-04-20
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.45 Å)
主引用文献Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
Structure, 20, 2012
4HN4
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BU of 4hn4 by Molmil
Tryptophan synthase in complex with alpha aminoacrylate E(A-A) form and the F9 inhibitor in the alpha site
分子名称: 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, BICINE, ...
著者Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L.
登録日2012-10-18
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.
Biochemistry, 52, 2013
4HJT
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BU of 4hjt by Molmil
Kinetic stabilization of transthyretin through covalent modification of K15 by (E)-N-(4-(4-hydroxy-3,5-dimethylstyryl)phenyl)propionamide
分子名称: N-{4-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]phenyl}propanamide, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2012-10-14
公開日2013-12-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis.
J.Am.Chem.Soc., 135, 2013
5V68
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BU of 5v68 by Molmil
Crystal structure of cell division protein FtsZ from Mycobacterium tuberculosis bounded via the T9 loop
分子名称: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Lazo, E.O, Ojima, I, Chowdhury, S.R, Awasthi, D, Jakoncic, J.
登録日2017-03-16
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Novel T9 loop conformation of filamenting temperature-sensitive mutant Z from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 75, 2019
4ALX
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BU of 4alx by Molmil
Crystal Structure of Ls-AChBP complexed with the potent nAChR antagonist DHbE
分子名称: (4bS,6S)-6-methoxy-1,4,6,7,9,10,12,13-octahydro-3H,5H-pyrano[4',3':3,4]pyrido[2,1-i]indol-3-one, ACETYLCHOLINE BINDING PROTEIN, MAGNESIUM ION, ...
著者Shahsavar, A, Kastrup, J.S, Nielsen, E.O, Kristensen, J.L, Gajhede, M, Balle, T.
登録日2012-03-06
公開日2012-08-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Lymnaea Stagnalis Achbp Complexed with the Potent Nachr Antagonist Dh-Betab-E Suggests a Unique Mode of Antagonism
Plos One, 7, 2012
2YKT
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BU of 2ykt by Molmil
Crystal structure of the I-BAR domain of IRSp53 (BAIAP2) in complex with an EHEC derived Tir peptide
分子名称: BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2, SULFATE ION, TRANSLOCATED INTIMIN RECEPTOR PROTEIN
著者de Groot, J.C, Schlueter, K, Carius, Y, Quedenau, C, Vingadassalom, D, Faix, J, Weiss, S.M, Reichelt, J, Standfuss-Gabisch, C, Lesser, C.F, Leong, J.M, Heinz, D.W, Buessow, K, Stradal, T.E.B.
登録日2011-05-30
公開日2011-09-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural Basis for Complex Formation between Human Irsp53 and the Translocated Intimin Receptor Tir of Enterohemorrhagic E. Coli.
Structure, 19, 2011
1LEL
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BU of 1lel by Molmil
The avidin BCAP complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin, E-AMINO BIOTINYL CAPROIC ACID
著者Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2002-04-10
公開日2002-11-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
J.Biol.Chem., 277, 2002
3BFB
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BU of 3bfb by Molmil
Crystal structure of a pheromone binding protein from Apis mellifera in complex with the 9-keto-2(E)-decenoic acid
分子名称: (2Z)-9-oxodec-2-enoic acid, CHLORIDE ION, GLYCEROL, ...
著者Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C.
登録日2007-11-21
公開日2008-06-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis of the honey bee PBP pheromone and pH-induced conformational change
J.Mol.Biol., 380, 2008
4HJS
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BU of 4hjs by Molmil
Kinetic stabilization of transthyretin through covalent modification of K15 by (E)-N-(4-(4-hydroxy-3,5-dimethylstyryl)ethanesulfonamide
分子名称: N-{4-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]phenyl}ethanesulfonamide, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2012-10-14
公開日2013-12-04
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis.
J.Am.Chem.Soc., 135, 2013
4TTG
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BU of 4ttg by Molmil
Beta-galactosidase (E. coli) in the presence of potassium chloride.
分子名称: Beta-galactosidase, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Juers, D.H.
登録日2014-06-20
公開日2015-03-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Elucidating factors important for monovalent cation selectivity in enzymes: E. coli beta-galactosidase as a model.
Phys Chem Chem Phys, 17, 2015
6I2K
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BU of 6i2k by Molmil
Structure of EV71 complexed with its receptor SCARB2
分子名称: 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhou, D, Zhao, Y, Kotecha, A, Fry, E.E, Kelly, J, Wang, X, Rao, Z, Rowlands, D.J, Ren, J, Stuart, D.I.
登録日2018-11-01
公開日2018-11-28
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.
Nat Microbiol, 4, 2019
1VUB
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BU of 1vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM E. COLI
分子名称: CCDB, CHLORIDE ION
著者Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
登録日1998-04-17
公開日1998-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
3VUB
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CCDB, A TOPOISOMERASE POISON FROM E. COLI
分子名称: CCDB, CHLORIDE ION
著者Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
登録日1998-04-17
公開日1998-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999

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