5XMM
| FLA-E*01801-167W/S | 分子名称: | Beta-2-microglobulin, Gag polyprotein, MHC class I antigen alpha chain | 著者 | Liang, R, Sun, Y, Wang, J, Wu, Y, Zhang, N, Xia, C. | 登録日 | 2017-05-15 | 公開日 | 2017-12-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides J. Virol., 92, 2018
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6UL5
| Crystal structure of HIV-1 reverse transcriptase (RT) in complex with 4-[(4-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy}thieno[3,2-d]pyrimidin-2-yl)amino]-2-fluorobenzonitrile (24b), a non-nucleoside RT inhibitor | 分子名称: | 1,2-ETHANEDIOL, 4-[(4-{4-[(E)-2-cyanoethenyl]-2,6-dimethylphenoxy}thieno[3,2-d]pyrimidin-2-yl)amino]-2-fluorobenzonitrile, MAGNESIUM ION, ... | 著者 | Ruiz, F.X, Pilch, A, Arnold, E. | 登録日 | 2019-10-06 | 公開日 | 2020-02-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel. J.Med.Chem., 63, 2020
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3G1P
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6I3Z
| Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin in complex with its antigen | 分子名称: | Alpha-1-antitrypsin, Fab 2H2 heavy chain, Fab 2H2 light chain, ... | 著者 | Laffranchi, M, Elliston, E.L.K, Miranda, E, Perez, J, Jagger, A.M, Fra, A, Lomas, D.A, Irving, J.A. | 登録日 | 2018-11-08 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. JCI Insight, 5, 2020
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1MJZ
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D97N | 分子名称: | INORGANIC PYROPHOSPHATASE | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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5NG1
| TUBULIN-MTC-zampanolide complex | 分子名称: | (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, (2~{Z},4~{E})-~{N}-[(~{S})-oxidanyl-[(1~{S},2~{E},5~{S},11~{R},17~{S},19~{R})-3,11,19-trimethyl-7,13-bis(oxidanylidene)-6,21-dioxabicyclo[15.3.1]henicos-2-en-5-yl]methyl]hexa-2,4-dienamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Field, J.J, Pera, B, Estevez Gallego, J, Calvo, E, Rodriguez-Salarichs, J, Saez-Calvo, G, Zuwerra, D, Jordi, M, Prota, A.E, Menchon, G, Miller, J.H, Altmann, K.-H, Diaz, J.F. | 登録日 | 2017-03-16 | 公開日 | 2017-10-25 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites. J. Nat. Prod., 81, 2018
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6WNY
| Crystal structure of BACE1 in complex with (Z)-fluoro-olefin containing compound 15 | 分子名称: | 6-[(Z)-2-{3-[(1S,5S,6S)-3-amino-5-methyl-1-(morpholine-4-carbonyl)-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4-fluorophenyl}-1-fluoroethenyl]pyridine-3-carbonitrile, Beta-secretase 1, IODIDE ION | 著者 | Whittington, D.A. | 登録日 | 2020-04-23 | 公開日 | 2020-06-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement. Bioorg.Med.Chem.Lett., 30, 2020
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2FQD
| Crystal Structures of E. coli Laccase CueO under different copper binding situations | 分子名称: | Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ... | 著者 | Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W. | 登録日 | 2006-01-18 | 公開日 | 2007-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of E. coli laccase CueO at different copper concentrations. Biochem.Biophys.Res.Commun., 354, 2007
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2FQE
| Crystal Structures of E. coli Laccase CueO under different copper binding situations | 分子名称: | Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ... | 著者 | Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W. | 登録日 | 2006-01-18 | 公開日 | 2007-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Crystal structures of E. coli laccase CueO at different copper concentrations. Biochem.Biophys.Res.Commun., 354, 2007
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2FQG
| Crystal Structures of E. coli Laccase CueO under different copper binding situations | 分子名称: | Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ... | 著者 | Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W. | 登録日 | 2006-01-18 | 公開日 | 2007-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of E. coli laccase CueO at different copper concentrations. Biochem.Biophys.Res.Commun., 354, 2007
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2FQF
| Crystal Structures of E. coli Laccase CueO under different copper binding situations | 分子名称: | Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ... | 著者 | Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W. | 登録日 | 2006-01-18 | 公開日 | 2007-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of E. coli laccase CueO at different copper concentrations. Biochem.Biophys.Res.Commun., 354, 2007
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2GAE
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1MJY
| STRUCTURE OF INORGANIC PYROPHOSPHATASE MUTANT D70N | 分子名称: | INORGANIC PYROPHOSPHATASE | 著者 | Oganesyan, V, Harutyunyan, E.H, Avaeva, S.M, Huber, R. | 登録日 | 1997-02-08 | 公開日 | 1997-12-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97. Biochemistry Mosc., 63, 1998
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3ET4
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3ET5
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4Q6D
| Crystal structure of human carbonic anhydrase isozyme II with 4-[(Z)-azepan-1-yldiazenyl]benzenesulfonamide | 分子名称: | 4-[(E)-azepan-1-yldiazenyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2014-04-22 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | 4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases. Molecules, 19, 2014
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3TAU
| Crystal Structure of a Putative Guanylate Monophosphaste Kinase from Listeria monocytogenes EGD-e | 分子名称: | Guanylate kinase, SODIUM ION, SULFATE ION | 著者 | Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Kwok, J, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-08-04 | 公開日 | 2011-08-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal Structure of a Putative Guanylate Monophosphaste Kinase from Listeria monocytogenes EGD-e To be Published
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2MT3
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4H71
| Human Plk1-PBD in complex with Poloxime ((E)-4-(hydroxyimino)-2-isopropyl-5-methylcyclohexa-2,5-dienone) | 分子名称: | 2-methyl-5-(1-methylethyl)cyclohexa-2,5-diene-1,4-dione 1-oxime, GLYCEROL, Serine/threonine-protein kinase PLK1 | 著者 | Yin, Z, Rehse, P.H. | 登録日 | 2012-09-19 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Thymoquinone Blocks pSer/pThr Recognition by Plk1 Polo-Box
Domain As a Phosphate Mimic Acs Chem.Biol., 8, 2013
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7UF8
| Structure of CtdP in complex with penicimutamide E and NADP+ | 分子名称: | 1,2-ETHANEDIOL, CtdP, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Rivera, S, Liu, Z, Newmister, S.A, Gao, X, Sherman, D.H. | 登録日 | 2022-03-22 | 公開日 | 2023-02-22 | 最終更新日 | 2023-04-19 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An NmrA-like enzyme-catalysed redox-mediated Diels-Alder cycloaddition with anti-selectivity. Nat.Chem., 15, 2023
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6JKM
| Crystal structure of BubR1 kinase domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | 登録日 | 2019-03-01 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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4S2U
| Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli | 分子名称: | MAGNESIUM ION, Ribose-phosphate pyrophosphokinase | 著者 | Timofeev, V.I, Abramchik, Y.A, Muravieva, T.I, Iaroslavtceva, A.K, Stepanenko, V.N, Zhukhlistova, N.E, Esipov, R.S, Kuranova, I.P. | 登録日 | 2015-01-23 | 公開日 | 2016-01-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli To be Published
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5D61
| MOA-Z-VAD-fmk complex, direct orientation | 分子名称: | 1,2-ETHANEDIOL, Agglutinin, CALCIUM ION, ... | 著者 | Cordara, G, van Eerde, A, Grahn, E.M, Goldstein, I.J, Krengel, U. | 登録日 | 2015-08-11 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An Unusual Member of the Papain Superfamily: Mapping the Catalytic Cleft of the Marasmius oreades agglutinin (MOA) with a Caspase Inhibitor. Plos One, 11, 2016
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7MT7
| Mtb 70S with P and E site tRNAs | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Cui, Z, Zhang, J. | 登録日 | 2021-05-13 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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6I1O
| Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FAB 2H2 heavy chain, FAB 2H2 light chain, ... | 著者 | Laffranchi, M, Elliston, E.L.K, Miranda, E, Perez, J, Fra, A, Lomas, D.A, Irving, J.A. | 登録日 | 2018-10-29 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. JCI Insight, 5, 2020
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