PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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1QB3	CRYSTAL STRUCTURE OF THE CELL CYCLE REGULATORY PROTEIN CKS1 分子名称: CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 著者 Bourne, Y, Watson, M.H, Arvai, A.S, Bernstein, S.L, Reed, S.I, Tainer, J.A. 登録日 1999-04-30 公開日 2000-08-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure and mutational analysis of the Saccharomyces cerevisiae cell cycle regulatory protein Cks1: implications for domain swapping, anion binding and protein interactions. Structure Fold.Des., 8, 2000
2NXP	Structure of NTD2 domain of the human TAF5 subunit of TFIID 分子名称: CALCIUM ION, Transcription initiation factor TFIID subunit 5 著者 Bhattacharya, S, Takada, S, Jacobson, R.H. 登録日 2006-11-17 公開日 2007-01-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structural analysis and dimerization potential of the human TAF5 subunit of TFIID. Proc.Natl.Acad.Sci.Usa, 104, 2007
1TAF	DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER 分子名称: TFIID TBP ASSOCIATED FACTOR 42, TFIID TBP ASSOCIATED FACTOR 62, ZINC ION 著者 Xie, X, Kokubo, T, Cohen, S.L, Mirza, U.A, Hoffmann, A, Chait, B.T, Roeder, R.G, Nakatani, Y, Burley, S.K. 登録日 1996-06-01 公開日 1996-12-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature, 380, 1996
2DOQ	crystal structure of Sfi1p/Cdc31p complex 分子名称: CALCIUM ION, Cell division control protein 31, SFI1p 著者 Li, S, Sandercock, A.M, Conduit, P.T, Robinson, C.V, Williams, R.L, Kilmartin, J.V. 登録日 2006-05-03 公開日 2006-06-27 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication. J.Cell Biol., 173, 2006
7LPE	Cryo-EM structure of full-length TRPV1 with capsaicin at 48 degrees Celsius, in an open state, class 1 分子名称: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Transient receptor potential cation channel subfamily V member 1, ... 著者 Kwon, D.H, Zhang, F, Suo, Y, Lee, S.-Y. 登録日 2021-02-11 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 Heat-dependent opening of TRPV1 in the presence of capsaicin. Nat.Struct.Mol.Biol., 28, 2021
7LPA	Cryo-EM structure of full-length TRPV1 with capsaicin at 4 degrees Celsius 分子名称: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, ... 著者 Kwon, D.H, Zhang, F, Suo, Y, Lee, S.-Y. 登録日 2021-02-11 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Heat-dependent opening of TRPV1 in the presence of capsaicin. Nat.Struct.Mol.Biol., 28, 2021
7LPB	Cryo-EM structure of full-length TRPV1 with capsaicin at 25 degrees Celsius 分子名称: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, ... 著者 Kwon, D.H, Zhang, F, Suo, Y, Lee, S.-Y. 登録日 2021-02-11 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Heat-dependent opening of TRPV1 in the presence of capsaicin. Nat.Struct.Mol.Biol., 28, 2021
7LPD	Cryo-EM structure of full-length TRPV1 with capsaicin at 48 degrees Celsius, in an intermediate state, class 2 分子名称: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Transient receptor potential cation channel subfamily V member 1, ... 著者 Kwon, D.H, Zhang, F, Suo, Y, Lee, S.-Y. 登録日 2021-02-11 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Heat-dependent opening of TRPV1 in the presence of capsaicin. Nat.Struct.Mol.Biol., 28, 2021
7LP9	Cryo-EM structure of full-length TRPV1 at 4 degrees Celsius 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, Phosphatidylinositol, ... 著者 Kwon, D.H, Zhang, F, Suo, Y, Lee, S.-Y. 登録日 2021-02-11 公開日 2021-07-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.63 Å) 主引用文献 Heat-dependent opening of TRPV1 in the presence of capsaicin. Nat.Struct.Mol.Biol., 28, 2021
7LPC	Cryo-EM structure of full-length TRPV1 at 48 degrees Celsius 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, Phosphatidylinositol, ... 著者 Kwon, D.H, Zhang, F, Suo, Y, Lee, S.-Y. 登録日 2021-02-11 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Heat-dependent opening of TRPV1 in the presence of capsaicin. Nat.Struct.Mol.Biol., 28, 2021
8FGW	Human IFT-A complex structures provide molecular insights into ciliary transport 分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... 著者 Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. 登録日 2022-12-12 公開日 2023-02-22 最終更新日 2023-04-12 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Human IFT-A complex structures provide molecular insights into ciliary transport. Cell Res., 33, 2023
5BPU	Crystal structure of Norrin, a Wnt signalling activator, Crystal Form I 分子名称: (GGL)EEE, (GGL)EEEEEE, Norrin 著者 Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y. 登録日 2015-05-28 公開日 2015-07-01 最終更新日 2019-07-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. Elife, 4, 2015
8FP5	CDK2 liganded with ATP and Mg2+ 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cyclin-dependent kinase 2, ... 著者 Schonbrunn, E, Sun, L. 登録日 2023-01-04 公開日 2023-05-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun, 14, 2023
8FF8	CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH 2-[(4-CYANOPHENYL)AMINO]-N-(4-PHENYLPYRIDIN-3-YL)PYRIMIDINE-4-CARBOXAMIDE 分子名称: 2-(4-cyanoanilino)-N-(4-phenylpyridin-3-yl)pyrimidine-4-carboxamide, Glycogen synthase kinase-3 beta 著者 Muckelbauer, J.K, Lewis, H.A. 登録日 2022-12-08 公開日 2023-06-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase-3 (GSK-3) Inhibitors. J.Med.Chem., 66, 2023
5BQB	Crystal structure of Norrin, a Wnt signalling activator, Crystal Form III 分子名称: CHLORIDE ION, CITRIC ACID, Norrin 著者 Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y. 登録日 2015-05-28 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. Elife, 4, 2015
8SV1	Caspase-1 complex with interleukin-18 分子名称: Caspase-1, Interleukin-18 著者 Dong, Y, Pascal, D, Jon, K, Wu, H. 登録日 2023-05-15 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Caspase-1 complex with interleukin-18 To Be Published
8F7L	Human NAMPT in complex with substrate NAM and small molecule activator ZN-29-S 分子名称: (3S)-N-[(1-benzothiophen-5-yl)methyl]-1-[(2P)-2-(3-fluoro-4-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-3-carboxamide, CHLORIDE ION, NICOTINAMIDE, ... 著者 Ratia, K, Xiong, R, Shen, Z, Thatcher, G.R. 登録日 2022-11-18 公開日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Human NAMPT in complex with substrate NAM and small molecule activator ZN-29-S To Be Published
5CL1	Complex structure of Norrin with human Frizzled 4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Maltose-binding periplasmic protein,Norrin 著者 Wang, Z, Ke, J, Shen, G, Cheng, Z, Xu, H.E, Xu, W. 登録日 2015-07-16 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of the Norrin-Frizzled 4 interaction. Cell Res., 25, 2015
5CER	Bd0816 Predatory Endopeptidase from Bdellovibrio bacteriovorus in complex with immunity protein Bd3460 分子名称: 1,2-ETHANEDIOL, Bd0816, Bd3460 著者 Lovering, A.L, Cadby, I.T, Lambert, C, Sockett, R.E. 登録日 2015-07-07 公開日 2015-12-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Ankyrin-mediated self-protection during cell invasion by the bacterial predator Bdellovibrio bacteriovorus. Nat Commun, 6, 2015
8FMU	Crystal structure of human Brachyury G177D variant in complex with SJF-4601 分子名称: N-(3-chloro-4-fluorophenyl)-3-[4-(dimethylamino)butanamido]-4-methoxybenzamide, T-box transcription factor T 著者 Bebenek, A, Linhares, B, Jaime-Figueroa, S, Butrin, A, Crews, C. 登録日 2022-12-24 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Discovery and Development of the First Selective Brachyury Degrader To Be Published
6EJL	Structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif 分子名称: 14-3-3 protein zeta/delta, Mitogen-activated protein kinase kinase kinase 5 著者 Petrvalska, O, Lentini Santo, D, Obsilova, V, Obsil, T. 登録日 2017-09-21 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.382 Å) 主引用文献 Crystal structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif To Be Published
4ORA	Crystal structure of a human calcineurin mutant 分子名称: CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... 著者 Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. 登録日 2014-02-11 公開日 2015-05-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.747 Å) 主引用文献 Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
6UGH	Cryo-EM structure of the apo form of human PRMT5:MEP50 complex at a resolution of 3.4 angstrom 分子名称: Methylosome protein 50, Protein arginine N-methyltransferase 5 著者 Zhou, W, Yadav, G.P, Jiang, Q.-X, Li, C. 登録日 2019-09-26 公開日 2020-12-09 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 A 3.4-angstrom cryo-EM structure of the apo form of hu-man PRMT5:MEP50 complex reveals sequential catalysis of symmetric methyl transfer To Be Published
3LW8	Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex A) 分子名称: GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ... 著者 Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. 登録日 2010-02-23 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285, 2010
8G25	Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 7.5 分子名称: Cathepsin-G, MAP domain-containing protein, Neutrophil elastase 著者 Mishra, N.B, Geisbrecht, B.V. 登録日 2023-02-03 公開日 2023-04-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2. J.Biol.Chem., 299, 2023

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